1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	W	I	G	W	L	E	F	D	V	L	L	G	D	V	R	S	L	K	Q	K	R	S	V	T	R	P	L	V	A	E	L	Q	R	K	F	S	V	S	A	A	E	T	G	S	H	D	L	Y	R	R	A	G	I	G	V	A	V	V	S
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.
Sequence		G	D	R	S	H	A	V	D	V	L	D	N	A	E	R	L	V	A	A	H	P	E	F	E	L	L	S	V	R	R	G	L	H	R	T	D	D
Secondary structure
SS confidence
Disorder																																			?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 33%) Beta strand ( 39%)

Rank Aligned region

PDB 1j27 chain A Region: 1 - 96 Aligned: 95 Modelled: 96 Confidence: 100.0% Identity: 23% Fold: Ferredoxin-like Superfamily: Hypothetical protein TT1725 Family: Hypothetical protein TT1725 Phyre2 PDB 3m20 chain A Region: 7 - 39 Aligned: 32 Modelled: 33 Confidence: 38.1% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:4-oxalocrotonate tautomerase, putative; PDBTitle: crystal structure of dmpi from archaeoglobus fulgidus determined to2 2.37 angstroms resolution Phyre2 PDB 4lkb chain A Region: 5 - 39 Aligned: 35 Modelled: 35 Confidence: 35.0% Identity: 23% PDB header:isomerase Chain: A: PDB Molecule:hypothetical protein alr4568/putative 4-oxalocrotonate PDBTitle: crystal structure of a putative 4-oxalocrotonate tautomerase from2 nostoc sp. pcc 7120 Phyre2 PDB 3byp chain A domain 1 Region: 5 - 39 Aligned: 35 Modelled: 35 Confidence: 34.9% Identity: 17% Fold: Alpha-lytic protease prodomain-like Superfamily: Cation efflux protein cytoplasmic domain-like Family: Cation efflux protein cytoplasmic domain-like Phyre2 PDB 6qek chain B Region: 5 - 39 Aligned: 35 Modelled: 35 Confidence: 33.8% Identity: 14% PDB header:transport protein Chain: B: PDB Molecule:magnetosome protein; PDBTitle: putative membrane tansporter, magnetosome protein mamm ctd2 [desulfamplus magnetovallimortis bw-1] Phyre2 PDB 1mww chain A Region: 5 - 39 Aligned: 35 Modelled: 35 Confidence: 26.7% Identity: 20% Fold: Tautomerase/MIF Superfamily: Tautomerase/MIF Family: Hypothetical protein HI1388.1 Phyre2 PDB 4fdx chain B Region: 7 - 39 Aligned: 33 Modelled: 33 Confidence: 22.0% Identity: 21% PDB header:isomerase Chain: B: PDB Molecule:4-oxalocrotonase tautomerase isozyme; PDBTitle: kinetic and structural characterization of the 4-oxalocrotonate2 tautomerase isozymes from methylibium petroleiphilum Phyre2 PDB 1p58 chain E Region: 62 - 83 Aligned: 22 Modelled: 22 Confidence: 19.7% Identity: 23% PDB header:virus Chain: E: PDB Molecule:envelope protein m; PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction Phyre2 PDB 2flz chain C Region: 6 - 82 Aligned: 76 Modelled: 77 Confidence: 19.1% Identity: 11% PDB header:hydrolase Chain: C: PDB Molecule:cis-3-chloroacrylic acid dehalogenase; PDBTitle: the x-ray structure of cis-3-chloroacrylic acid dehalogenase (cis-2 caad) with a sulfate ion bound in the active site Phyre2 PDB 1p58 chain F Region: 62 - 83 Aligned: 22 Modelled: 22 Confidence: 18.8% Identity: 23% PDB header:virus Chain: F: PDB Molecule:envelope protein m; PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction Phyre2 PDB 4faz chain B Region: 7 - 39 Aligned: 33 Modelled: 33 Confidence: 18.0% Identity: 18% PDB header:isomerase Chain: B: PDB Molecule:4-oxalocrotonate isomerase protein; PDBTitle: kinetic and structural characterization of the 4-oxalocrotonate2 tautomerase isozymes from methylibium petroleiphilum Phyre2 PDB 2op8 chain A Region: 7 - 39 Aligned: 33 Modelled: 33 Confidence: 17.8% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:probable tautomerase ywhb; PDBTitle: crystal structure of ywhb- homologue of 4-oxalocrotonate tautomerase Phyre2 PDB 3ry0 chain A Region: 7 - 38 Aligned: 32 Modelled: 32 Confidence: 17.5% Identity: 19% PDB header:isomerase Chain: A: PDB Molecule:putative tautomerase; PDBTitle: crystal structure of tomn, a 4-oxalocrotonate tautomerase homologue in2 tomaymycin biosynthetic pathway Phyre2 PDB 2vd2 chain A Region: 17 - 34 Aligned: 18 Modelled: 18 Confidence: 17.1% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase; PDBTitle: the crystal structure of hisg from b. subtilis Phyre2 PDB 5m8h chain H Region: 17 - 37 Aligned: 21 Modelled: 21 Confidence: 17.1% Identity: 19% PDB header:transferase Chain: H: PDB Molecule:atp phosphoribosyltransferase; PDBTitle: atp phosphoribosyltransferase (hiszg atpprt) from psychrobacter2 arcticus Phyre2 PDB 2bm0 chain A domain 4 Region: 25 - 40 Aligned: 16 Modelled: 16 Confidence: 17.0% Identity: 38% Fold: Ferredoxin-like Superfamily: EF-G C-terminal domain-like Family: EF-G/eEF-2 domains III and V Phyre2 PDB 1ve4 chain A domain 1 Region: 17 - 34 Aligned: 18 Modelled: 18 Confidence: 16.7% Identity: 44% Fold: Periplasmic binding protein-like II Superfamily: Periplasmic binding protein-like II Family: Phosphate binding protein-like Phyre2 PDB 1iwg chain A domain 3 Region: 4 - 85 Aligned: 82 Modelled: 82 Confidence: 16.3% Identity: 13% Fold: Ferredoxin-like Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Phyre2 PDB 2mcf chain A Region: 24 - 47 Aligned: 24 Modelled: 24 Confidence: 15.1% Identity: 17% PDB header:unknown function Chain: A: PDB Molecule:tgam_1934; PDBTitle: nmr structure of tgam_1934 Phyre2 PDB 1otf chain A Region: 7 - 39 Aligned: 33 Modelled: 33 Confidence: 13.6% Identity: 12% Fold: Tautomerase/MIF Superfamily: Tautomerase/MIF Family: 4-oxalocrotonate tautomerase-like Phyre2 1 d1j27a_ 2 c3m20A_ 3 c4lkbA_ 4 d3bypa1 5 c6qekB_ 6 d1mwwa_ 7 c4fdxB_ 8 c1p58E_ 9 c2flzC_ 10 c1p58F_ 11 c4fazB_ 12 c2op8A_ 13 c3ry0A_ 14 c2vd2A_ 15 c5m8hH_ 16 d2bm0a4 17 d1ve4a1 18 d1iwga3 19 c2mcfA_ 20 d1otfa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69