1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	V	I	L	L	R	H	A	R	S	T	S	N	T	A	G	V	L	A	G	R	S	G	V	D	L	D	E	K	G	R	E	Q	A	T	G	L	I	D	R	I	G	D	L	P	I	R	A	V	A	S	S	P	M	L	R	C	Q	R
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	V	E	P	L	A	E	A	L	C	L	E	P	L	I	D	D	R	F	S	E	V	D	Y	G	E	W	T	G	R	K	I	G	D	L	V	D	E	P	L	W	R	V	V	Q	A	H	P	S	A	A	V	F	P	G	G	E	G	L	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	V	Q	T	R	A	V	A	A	V	R	E	H	D	R	R	L	A	D	Q	H	G	H	D	V	L	W	L	A	C	T	H	G	D	V	I	K	A	V	I	A	D	A	F	G	M	H	L	D	S	F	Q	R	I	T	A	D	P	G	S
Secondary structure
SS confidence
Disorder																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Sequence		V	S	V	V	R	Y	T	Q	L	R	P	F	V	L	H	V	N	H	T	G	A	R	L	A	P	A	L	Q	A	A	A	S	A	Q	G	A	S	P	E	P	N	A	A	V	P	P	G	D	A	V	I	G	G	S	T	D
Secondary structure
SS confidence
Disorder																													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 13%) Alpha helix ( 36%) Beta strand ( 17%)

Rank Aligned region

PDB 4ij5 chain B Region: 1 - 205 Aligned: 199 Modelled: 205 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: B: PDB Molecule:phosphoserine phosphatase 1; PDBTitle: crystal structure of a novel-type phosphoserine phosphatase from2 hydrogenobacter thermophilus tk-6 Phyre2 PDB 1e58 chain A Region: 1 - 197 Aligned: 194 Modelled: 197 Confidence: 100.0% Identity: 19% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 4emb chain D Region: 2 - 209 Aligned: 205 Modelled: 208 Confidence: 100.0% Identity: 17% PDB header:isomerase Chain: D: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of a phosphoglycerate mutase gpma from borrelia2 burgdorferi b31 Phyre2 PDB 5zkk chain A Region: 1 - 203 Aligned: 195 Modelled: 203 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:phosphoglycerate mutase family protein, putative; PDBTitle: crystal structure of phosphoserine phosphatase from entamoeba2 histolytica Phyre2 PDB 4pz9 chain B Region: 2 - 200 Aligned: 196 Modelled: 199 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:glucosyl-3-phosphoglycerate phosphatase; PDBTitle: the native structure of mycobacterial glucosyl-3-phosphoglycerate2 phosphatase rv2419c Phyre2 PDB 3ll4 chain B Region: 2 - 190 Aligned: 189 Modelled: 189 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein ykr043c; PDBTitle: structure of the h13a mutant of ykr043c in complex with fructose-1,6-2 bisphosphate Phyre2 PDB 6e4b chain C Region: 1 - 200 Aligned: 195 Modelled: 200 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: C: PDB Molecule:adenosylcobalamin/alpha-ribazole phosphatase; PDBTitle: the crystal structure of a putative alpha-ribazole-5'-p phosphatase2 from escherichia coli str. k-12 substr. mg1655 Phyre2 PDB 3f3k chain A Region: 1 - 191 Aligned: 191 Modelled: 191 Confidence: 100.0% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ykr043c; PDBTitle: the structure of uncharacterized protein ykr043c from saccharomyces2 cerevisiae. Phyre2 PDB 1yjx chain D Region: 2 - 201 Aligned: 197 Modelled: 197 Confidence: 100.0% Identity: 20% PDB header:isomerase, hydrolase Chain: D: PDB Molecule:phosphoglycerate mutase 1; PDBTitle: crystal structure of human b type phosphoglycerate mutase Phyre2 PDB 1xq9 chain A Region: 2 - 197 Aligned: 193 Modelled: 196 Confidence: 100.0% Identity: 22% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 5vve chain A Region: 1 - 197 Aligned: 194 Modelled: 194 Confidence: 100.0% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglycerate mutase from naegleria fowleri Phyre2 PDB 1h2e chain A Region: 1 - 202 Aligned: 197 Modelled: 202 Confidence: 100.0% Identity: 24% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 3r7a chain A Region: 1 - 201 Aligned: 195 Modelled: 198 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:phosphoglycerate mutase, putative; PDBTitle: crystal structure of phosphoglycerate mutase from bacillus anthracis2 str. sterne Phyre2 PDB 2a6p chain A Region: 1 - 201 Aligned: 189 Modelled: 201 Confidence: 100.0% Identity: 25% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible phosphoglycerate mutase gpm2; PDBTitle: structure solution to 2.2 angstrom and functional characterisation of2 the open reading frame rv3214 from mycobacterium tuberculosis Phyre2 PDB 2yn0 chain A Region: 2 - 207 Aligned: 205 Modelled: 205 Confidence: 100.0% Identity: 18% PDB header:transcription Chain: A: PDB Molecule:transcription factor tau 55 kda subunit; PDBTitle: tau55 histidine phosphatase domain Phyre2 PDB 3ezn chain B Region: 1 - 196 Aligned: 193 Modelled: 193 Confidence: 100.0% Identity: 22% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglyceromutase from burkholderia2 pseudomallei 1710b Phyre2 PDB 5um0 chain A Region: 1 - 196 Aligned: 193 Modelled: 193 Confidence: 100.0% Identity: 20% PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of 2,3-bisphosphoglycerate-dependent2 phosphoglycerate mutase from neisseria gonorrhoeae Phyre2 PDB 1qhf chain A Region: 2 - 190 Aligned: 186 Modelled: 186 Confidence: 100.0% Identity: 18% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 1rii chain A Region: 1 - 189 Aligned: 186 Modelled: 189 Confidence: 100.0% Identity: 20% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 3dcy chain A Region: 1 - 202 Aligned: 200 Modelled: 202 Confidence: 100.0% Identity: 20% PDB header:apoptosis regulator Chain: A: PDB Molecule:regulator protein; PDBTitle: crystal structure a tp53-induced glycolysis and apoptosis regulator2 protein from homo sapiens. Phyre2 1 c4ij5B_ 2 d1e58a_ 3 c4embD_ 4 c5zkkA_ 5 c4pz9B_ 6 c3ll4B_ 7 c6e4bC_ 8 c3f3kA_ 9 c1yjxD_ 10 d1xq9a_ 11 c5vveA_ 12 d1h2ea_ 13 c3r7aA_ 14 c2a6pA_ 15 c2yn0A_ 16 c3eznB_ 17 c5um0A_ 18 d1qhfa_ 19 d1riia_ 20 c3dcyA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99