1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	R	Y	F	Y	D	T	E	F	I	E	D	G	H	T	I	E	L	I	S	I	G	V	V	A	E	D	G	R	E	Y	Y	A	V	S	T	E	F	D	P	E	R	A	G	S	W	V	R	T	H	V	L	P	K	L	P	P	P	A	S
Secondary structure
SS confidence
Disorder		?	?																																																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	L	W	R	S	R	Q	Q	I	R	L	D	L	E	E	F	L	R	I	D	G	T	D	S	I	E	L	W	A	W	V	G	A	Y	D	H	V	A	L	C	Q	L	W	G	P	M	T	A	L	P	P	T	V	P	R	F	T	R	E	L
Secondary structure
SS confidence
Disorder			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.
Sequence		R	Q	L	W	E	D	R	G	C	P	R	M	P	P	R	P	R	D	V	H	D	A	L	V	D	A	R	D	Q	L	R	R	F	R	L	I	T	S	T	D	D	A	G	R	G	A	A	R
Secondary structure
SS confidence
Disorder								?			?	?	?	?	?	?	?	?	?																								?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 43%) Beta strand ( 15%)

Rank Aligned region

PDB 4hec chain B Region: 1 - 161 Aligned: 161 Modelled: 161 Confidence: 100.0% Identity: 100% PDB header:unknown function Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium tuberculosis Phyre2 PDB 5cy4 chain C Region: 3 - 158 Aligned: 153 Modelled: 156 Confidence: 99.6% Identity: 16% PDB header:oxidoreductase Chain: C: PDB Molecule:oligoribonuclease; PDBTitle: crystal structure of an oligoribonuclease from acinetobacter baumannii Phyre2 PDB 2igi chain A domain 1 Region: 1 - 159 Aligned: 156 Modelled: 159 Confidence: 99.6% Identity: 14% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 2f96 chain A domain 1 Region: 3 - 165 Aligned: 163 Modelled: 162 Confidence: 99.6% Identity: 16% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 2gbz chain A Region: 3 - 165 Aligned: 160 Modelled: 163 Confidence: 99.6% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: the crystal structure of xc847 from xanthomonas campestris: a 3-52 oligoribonuclease of dnaq fold family with a novel opposingly-shifted3 helix Phyre2 PDB 2p1j chain B Region: 3 - 165 Aligned: 155 Modelled: 163 Confidence: 99.6% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii polc-type; PDBTitle: crystal structure of a polc-type dna polymerase iii exonuclease domain2 from thermotoga maritima Phyre2 PDB 6n6j chain B Region: 3 - 158 Aligned: 153 Modelled: 156 Confidence: 99.5% Identity: 14% PDB header:rna binding protein/rna Chain: B: PDB Molecule:rna exonuclease 2 homolog,small fragment nuclease; PDBTitle: human rexo2 bound to paa Phyre2 PDB 3tr8 chain A Region: 3 - 159 Aligned: 154 Modelled: 157 Confidence: 99.5% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: structure of an oligoribonuclease (orn) from coxiella burnetii Phyre2 PDB 6n6d chain A Region: 3 - 158 Aligned: 156 Modelled: 156 Confidence: 99.5% Identity: 12% PDB header:rna binding protein/rna Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: vibrio cholerae oligoribonuclease bound to pag Phyre2 PDB 5z9x chain A Region: 3 - 157 Aligned: 143 Modelled: 155 Confidence: 99.5% Identity: 16% PDB header:plant protein/rna Chain: A: PDB Molecule:small rna degrading nuclease 1; PDBTitle: arabidopsis small rna degrading nuclease 1 in complex with an rna2 substrate Phyre2 PDB 1wlj chain A Region: 3 - 165 Aligned: 153 Modelled: 163 Confidence: 99.5% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 1j9a chain A Region: 3 - 158 Aligned: 153 Modelled: 156 Confidence: 99.5% Identity: 15% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 1y97 chain A domain 1 Region: 3 - 159 Aligned: 157 Modelled: 157 Confidence: 99.5% Identity: 13% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 6a4d chain A Region: 3 - 158 Aligned: 153 Modelled: 156 Confidence: 99.5% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: pnp-tmp bound oligoribonuclease (orn) from colwellia psychrerythraea2 strain 34h Phyre2 PDB 3b6o chain A domain 1 Region: 3 - 159 Aligned: 157 Modelled: 157 Confidence: 99.5% Identity: 15% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 2qxf chain A domain 1 Region: 3 - 160 Aligned: 146 Modelled: 158 Confidence: 99.4% Identity: 10% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 4fzx chain C Region: 1 - 160 Aligned: 148 Modelled: 153 Confidence: 99.4% Identity: 18% PDB header:hydrolase/dna Chain: C: PDB Molecule:exodeoxyribonuclease 10; PDBTitle: exonuclease x in complex with 3' overhanging duplex dna Phyre2 PDB 2gui chain A domain 1 Region: 3 - 157 Aligned: 147 Modelled: 155 Confidence: 99.4% Identity: 19% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 4wbq chain A Region: 3 - 160 Aligned: 149 Modelled: 158 Confidence: 99.4% Identity: 17% PDB header:rna binding protein Chain: A: PDB Molecule:qde-2-interacting protein; PDBTitle: crystal structure of the exonuclease domain of qip (qde-2 interacting2 protein) solved by native-sad phasing. Phyre2 PDB 4rg8 chain A Region: 3 - 160 Aligned: 147 Modelled: 158 Confidence: 99.4% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:exonuclease i; PDBTitle: structural and biochemical studies of a moderately thermophilic2 exonuclease i from methylocaldum szegediense Phyre2 1 c4hecB_ 2 c5cy4C_ 3 d2igia1 4 d2f96a1 5 c2gbzA_ 6 c2p1jB_ 7 c6n6jB_ 8 c3tr8A_ 9 c6n6dA_ 10 c5z9xA_ 11 d1wlja_ 12 d1j9aa_ 13 d1y97a1 14 c6a4dA_ 15 d3b6oa1 16 d2qxfa1 17 c4fzxC_ 18 d2guia1 19 c4wbqA_ 20 c4rg8A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99