1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	W	Y	Y	L	F	K	Y	I	F	M	G	P	L	F	T	L	L	G	R	P	K	V	E	G	L	E	Y	I	P	S	S	G	P	A	I	L	A	S	N	H	L	A	V	A	D	S	F	Y	L	P	L	V	V	R	R	R	I	W	F
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	K	S	E	Y	F	T	G	T	G	L	K	G	W	I	N	R	W	F	Y	S	V	S	G	Q	V	P	I	D	R	T	N	A	D	S	A	Q	G	A	L	Q	T	A	V	V	L	L	G	Q	G	K	L	L	G	M	Y	P	E	G
Secondary structure
SS confidence
Disorder																																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	R	S	P	D	G	R	L	Y	K	G	K	T	G	L	A	R	L	A	L	H	T	G	V	P	V	I	P	V	A	M	I	G	T	N	V	V	N	P	P	G	R	K	M	L	R	F	G	R	V	T	V	R	F	G	K	P	M	D	F
Secondary structure
SS confidence
Disorder							?		?			?																													?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	R	F	E	G	L	A	G	N	H	F	I	E	R	A	V	T	D	E	V	I	Y	E	L	M	G	L	S	G	Q	E	Y	V	D	I	Y	A	A	S	V	K	D	G	R	N	A	G	G	A	G	A	N	P	N	S	T	D	A	A	R
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?																						?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		I	P	E	T	A	A	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 43%) Beta strand ( 16%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 5kym chain A Region: 2 - 206 Aligned: 193 Modelled: 205 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:1-acyl-sn-glycerol-3-phosphate acyltransferase; PDBTitle: crystal structure of the 1-acyl-sn-glycerophosphate (lpa)2 acyltransferase, plsc, from thermotoga maritima Phyre2 PDB 5f34 chain A Region: 3 - 210 Aligned: 187 Modelled: 208 Confidence: 99.6% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannoside acyltransferase; PDBTitle: crystal structure of membrane associated pata from mycobacterium2 smegmatis in complex with s-hexadecyl coenzyme a - p21 space group Phyre2 PDB 5knk chain B Region: 21 - 229 Aligned: 183 Modelled: 209 Confidence: 99.5% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:lipid a biosynthesis lauroyl acyltransferase; PDBTitle: lipid a secondary acyltransferase lpxm from acinetobacter baumannii2 with catalytic residue substitution (e127a) Phyre2 PDB 1iuq chain A Region: 3 - 206 Aligned: 201 Modelled: 203 Confidence: 99.2% Identity: 19% Fold: Glycerol-3-phosphate (1)-acyltransferase Superfamily: Glycerol-3-phosphate (1)-acyltransferase Family: Glycerol-3-phosphate (1)-acyltransferase Phyre2 PDB 5vrh chain A Region: 90 - 147 Aligned: 58 Modelled: 58 Confidence: 23.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:apolipoprotein n-acyltransferase; PDBTitle: apolipoprotein n-acyltransferase c387s active site mutant Phyre2 PDB 3hkx chain A Region: 88 - 147 Aligned: 60 Modelled: 60 Confidence: 16.7% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:amidase; PDBTitle: crystal structure analysis of an amidase from nesterenkonia sp. Phyre2 PDB 4cyy chain A Region: 95 - 147 Aligned: 53 Modelled: 53 Confidence: 15.7% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:pantetheinase; PDBTitle: the structure of vanin-1: defining the link between metabolic disease,2 oxidative stress and inflammation Phyre2 PDB 1yj5 chain B Region: 76 - 158 Aligned: 77 Modelled: 83 Confidence: 14.9% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:5' polynucleotide kinase-3' phosphatase catalytic domain; PDBTitle: molecular architecture of mammalian polynucleotide kinase, a dna2 repair enzyme Phyre2 PDB 3zvm chain A Region: 76 - 158 Aligned: 77 Modelled: 83 Confidence: 13.3% Identity: 18% PDB header:hydrolase/transferase/dna Chain: A: PDB Molecule:bifunctional polynucleotide phosphatase/kinase; PDBTitle: the structural basis for substrate recognition by mammalian2 polynucleotide kinase 3' phosphatase Phyre2 PDB 1to6 chain A Region: 110 - 205 Aligned: 91 Modelled: 96 Confidence: 11.9% Identity: 20% Fold: Glycerate kinase I Superfamily: Glycerate kinase I Family: Glycerate kinase I Phyre2 PDB 2e11 chain B Region: 89 - 147 Aligned: 59 Modelled: 59 Confidence: 9.7% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:hydrolase; PDBTitle: the crystal structure of xc1258 from xanthomonas campestris: a cn-2 hydrolase superfamily protein with an arsenic adduct in the active3 site Phyre2 PDB 4chm chain B Region: 92 - 148 Aligned: 57 Modelled: 57 Confidence: 9.2% Identity: 19% PDB header:cell cycle Chain: B: PDB Molecule:imc sub-compartment protein isp1; PDBTitle: structure of inner membrane complex (imc) sub-compartment protein 12 (isp1) from toxoplasma gondii Phyre2 PDB 2vhh chain A Region: 88 - 147 Aligned: 60 Modelled: 60 Confidence: 9.1% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:cg3027-pa; PDBTitle: crystal structure of a pyrimidine degrading enzyme from2 drosophila melanogaster Phyre2 PDB 5kha chain A Region: 95 - 147 Aligned: 53 Modelled: 53 Confidence: 7.5% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad+ synthetase; PDBTitle: structure of glutamine-dependent nad+ synthetase from acinetobacter2 baumannii in complex with adenosine diphosphate (adp) Phyre2 PDB 3cwc chain B Region: 105 - 150 Aligned: 46 Modelled: 46 Confidence: 7.5% Identity: 24% PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 Phyre2 PDB 4chj chain A Region: 87 - 148 Aligned: 62 Modelled: 62 Confidence: 7.3% Identity: 13% PDB header:cell cycle Chain: A: PDB Molecule:imc sub-compartment protein isp3; PDBTitle: structure of inner membrane complex (imc) sub-compartment2 protein 3 (isp3) from toxoplasma gondii Phyre2 PDB 6ftq chain A Region: 88 - 119 Aligned: 32 Modelled: 32 Confidence: 6.5% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:beta-ureidopropionase; PDBTitle: crystal structure of human beta-ureidopropionase (beta-alanine2 synthase) - mutant t299c Phyre2 PDB 2zo7 chain A Region: 16 - 35 Aligned: 18 Modelled: 20 Confidence: 6.3% Identity: 28% PDB header:luminescent protein Chain: A: PDB Molecule:cyan/green-emitting gfp-like protein, kusabira-cyan mutant PDBTitle: crystal structure of a kusabira-cyan mutant (kcy-r1), a cyan/green-2 emitting gfp-like protein Phyre2 PDB 1ems chain B Region: 95 - 148 Aligned: 54 Modelled: 54 Confidence: 6.2% Identity: 11% PDB header:antitumor protein Chain: B: PDB Molecule:nit-fragile histidine triad fusion protein; PDBTitle: crystal structure of the c. elegans nitfhit protein Phyre2 PDB 3wuy chain A Region: 95 - 123 Aligned: 29 Modelled: 29 Confidence: 5.9% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:nitrilase; PDBTitle: crystal structure of nit6803 Phyre2 1 c5kymA_ 2 c5f34A_ 3 c5knkB_ 4 d1iuqa_ 5 c5vrhA_ 6 c3hkxA_ 7 c4cyyA_ 8 c1yj5B_ 9 c3zvmA_ 10 d1to6a_ 11 c2e11B_ 12 c4chmB_ 13 c2vhhA_ 14 c5khaA_ 15 c3cwcB_ 16 c4chjA_ 17 c6ftqA_ 18 c2zo7A_ 19 c1emsB_ 20 c3wuyA_ 21 22 23