1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	H	I	E	A	R	L	F	E	F	V	A	A	F	F	V	V	T	A	V	L	Y	G	V	L	T	S	M	F	A	T	G	G	V	E	W	A	G	T	T	A	L	A	L	T	G	G	M	A	L	I	V	A	T	F	F	R	F	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	R	L	D	S	R	P	E	D	Y	E	G	A	E	I	S	D	G	A	G	E	L	G	F	F	S	P	H	S	W	W	P	I	M	V	A	L	S	G	S	V	A	A	V	G	I	A	L	W	L	P	W	L	I	A	A	G	V	A	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.
Sequence		I	L	A	S	A	A	G	L	V	F	E	Y	Y	V	G	P	E	K	H
Secondary structure
SS confidence
Disorder																?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 74%) Beta strand ( 0%) TM helix ( 53%) (View membrane topology prediction)

Rank Aligned region

PDB 6hwh chain X Region: 1 - 139 Aligned: 139 Modelled: 139 Confidence: 100.0% Identity: 78% PDB header:electron transport Chain: X: PDB Molecule:cytochrome c oxidase polypeptide 4; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 2yev chain A Region: 68 - 138 Aligned: 70 Modelled: 71 Confidence: 89.7% Identity: 16% PDB header:electron transport Chain: A: PDB Molecule:cytochrome c oxidase polypeptide i+iii; PDBTitle: structure of caa3-type cytochrome oxidase Phyre2 PDB 1qle chain C Region: 86 - 137 Aligned: 51 Modelled: 52 Confidence: 88.7% Identity: 33% Fold: Cytochrome c oxidase subunit III-like Superfamily: Cytochrome c oxidase subunit III-like Family: Cytochrome c oxidase subunit III-like Phyre2 PDB 1m56 chain C Region: 86 - 134 Aligned: 48 Modelled: 49 Confidence: 87.1% Identity: 27% Fold: Cytochrome c oxidase subunit III-like Superfamily: Cytochrome c oxidase subunit III-like Family: Cytochrome c oxidase subunit III-like Phyre2 PDB 1v54 chain C Region: 84 - 134 Aligned: 51 Modelled: 51 Confidence: 86.0% Identity: 20% Fold: Cytochrome c oxidase subunit III-like Superfamily: Cytochrome c oxidase subunit III-like Family: Cytochrome c oxidase subunit III-like Phyre2 PDB 6hu9 chain O Region: 89 - 134 Aligned: 46 Modelled: 46 Confidence: 80.6% Identity: 22% PDB header:oxidoreductase/electron transport Chain: O: PDB Molecule:cytochrome c1, heme protein, mitochondrial; PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae Phyre2 PDB 1g29 chain 1 domain 3 Region: 63 - 77 Aligned: 15 Modelled: 15 Confidence: 41.6% Identity: 33% Fold: OB-fold Superfamily: MOP-like Family: ABC-transporter additional domain Phyre2 PDB 6btm chain C Region: 62 - 119 Aligned: 57 Modelled: 58 Confidence: 39.9% Identity: 11% PDB header:membrane protein Chain: C: PDB Molecule:alternative complex iii subunit c; PDBTitle: structure of alternative complex iii from flavobacterium johnsoniae2 (wild type) Phyre2 PDB 3eh4 chain A Region: 37 - 105 Aligned: 69 Modelled: 69 Confidence: 38.1% Identity: 9% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase subunit 1; PDBTitle: structure of the reduced form of cytochrome ba3 oxidase from thermus2 thermophilus Phyre2 PDB 2l9u chain B Region: 113 - 139 Aligned: 27 Modelled: 27 Confidence: 36.8% Identity: 22% PDB header:membrane protein Chain: B: PDB Molecule:receptor tyrosine-protein kinase erbb-3; PDBTitle: spatial structure of dimeric erbb3 transmembrane domain Phyre2 PDB 6mup chain K Region: 60 - 70 Aligned: 11 Modelled: 11 Confidence: 36.3% Identity: 45% PDB header:nuclear protein Chain: K: PDB Molecule:centromere protein c; PDBTitle: cenp-a nucleosome bound by two copies of cenp-c(cd) and two copies2 cenp-n(nt) Phyre2 PDB 6mup chain L Region: 60 - 70 Aligned: 11 Modelled: 11 Confidence: 35.4% Identity: 45% PDB header:nuclear protein Chain: L: PDB Molecule:centromere protein c; PDBTitle: cenp-a nucleosome bound by two copies of cenp-c(cd) and two copies2 cenp-n(nt) Phyre2 PDB 6muo chain K Region: 60 - 70 Aligned: 11 Modelled: 11 Confidence: 35.4% Identity: 45% PDB header:nuclear protein Chain: K: PDB Molecule:centromere protein c; PDBTitle: cenp-a nucleosome bound by two copies of cenp-c(cd) and one copy cenp-2 n(nt) Phyre2 PDB 1xme chain A domain 1 Region: 37 - 105 Aligned: 69 Modelled: 69 Confidence: 30.7% Identity: 9% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 2l9u chain A Region: 113 - 139 Aligned: 27 Modelled: 27 Confidence: 30.1% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-3; PDBTitle: spatial structure of dimeric erbb3 transmembrane domain Phyre2 PDB 4dji chain A Region: 2 - 90 Aligned: 89 Modelled: 89 Confidence: 26.6% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:probable glutamate/gamma-aminobutyrate antiporter; PDBTitle: structure of glutamate-gaba antiporter gadc Phyre2 PDB 3ewe chain D Region: 59 - 99 Aligned: 31 Modelled: 41 Confidence: 22.8% Identity: 16% PDB header:protein transport,structural protein Chain: D: PDB Molecule:nucleoporin nup85; PDBTitle: crystal structure of the nup85/seh1 complex Phyre2 PDB 2bm8 chain A domain 1 Region: 63 - 90 Aligned: 28 Modelled: 28 Confidence: 22.2% Identity: 36% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: CmcI-like Phyre2 PDB 5xav chain B Region: 87 - 96 Aligned: 10 Modelled: 10 Confidence: 22.1% Identity: 50% PDB header:biosynthetic protein Chain: B: PDB Molecule:intracellular polyhydroxyalkanoate synthase; PDBTitle: structure of phac from chromobacterium sp. usm2 Phyre2 PDB 2lx0 chain A Region: 88 - 114 Aligned: 24 Modelled: 27 Confidence: 20.1% Identity: 25% PDB header:membrane protein Chain: A: PDB Molecule:membrane fusion protein p14; PDBTitle: arced helix (arch) nmr structure of the reovirus p14 fusion-associated2 small transmembrane (fast) protein transmembrane domain (tmd) in3 dodecyl phosphocholine (dpc) micelles Phyre2 1 c6hwhX_ 2 c2yevA_ 3 d1qlec_ 4 d1m56c_ 5 d1v54c_ 6 c6hu9o_ 7 d1g2913 8 c6btmC_ 9 c3eh4A_ 10 c2l9uB_ 11 c6mupK_ 12 c6mupL_ 13 c6muoK_ 14 d1xmea1 15 c2l9uA_ 16 c4djiA_ 17 c3eweD_ 18 d2bm8a1 19 c5xavB_ 20 c2lx0A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74