1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	D	D	S	N	D	T	A	T	D	V	E	P	D	Y	R	F	T	L	A	N	E	R	T	F	L	A	W	Q	R	T	A	L	G	L	L	A	A	A	V	A	L	V	Q	L	V	P	E	L	T	I	P	G	A	R	Q	V	L	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?																																			?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	V	L	A	I	L	A	I	L	T	S	G	M	G	L	L	R	W	Q	Q	A	D	R	A	M	R	R	H	L	P	L	P	R	H	P	T	P	G	Y	L	A	V	G	L	C	V	V	G	V	V	A	L	A	L	V	V	A	K	A	I
Secondary structure
SS confidence
Disorder																												?	?	?	?	?																												?	?
Disorder confidence
		.	.
Sequence		T	G
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 72%) Beta strand ( 0%) TM helix ( 51%) (View membrane topology prediction)

Rank Aligned region

PDB 3jbr chain E Region: 33 - 121 Aligned: 84 Modelled: 89 Confidence: 55.2% Identity: 7% PDB header:membrane protein Chain: E: PDB Molecule:voltage-dependent calcium channel gamma-1 subunit; PDBTitle: cryo-em structure of the rabbit voltage-gated calcium channel cav1.12 complex at 4.2 angstrom Phyre2 PDB 4hr1 chain A Region: 27 - 37 Aligned: 11 Modelled: 11 Confidence: 39.9% Identity: 45% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: structure of pav1-137, a protein from the virus pav1 that infects2 pyrococcus abyssi. Phyre2 PDB 4ymk chain A Region: 3 - 78 Aligned: 74 Modelled: 76 Confidence: 34.1% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:acyl-coa desaturase 1; PDBTitle: crystal structure of stearoyl-coenzyme a desaturase 1 Phyre2 PDB 2yev chain B Region: 54 - 115 Aligned: 62 Modelled: 62 Confidence: 29.6% Identity: 3% PDB header:electron transport Chain: B: PDB Molecule:cytochrome c oxidase subunit 2; PDBTitle: structure of caa3-type cytochrome oxidase Phyre2 PDB 6c4v chain A Region: 16 - 29 Aligned: 12 Modelled: 14 Confidence: 29.5% Identity: 58% PDB header:transport protein Chain: A: PDB Molecule:polyketide synthase pks13; PDBTitle: 1.9 angstrom resolution crystal structure of acyl carrier protein2 domain (residues 1350-1461) of polyketide synthase pks13 from3 mycobacterium tuberculosis Phyre2 PDB 5ldx chain Z Region: 60 - 87 Aligned: 28 Modelled: 28 Confidence: 18.6% Identity: 21% PDB header:oxidoreductase Chain: Z: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: structure of mammalian respiratory complex i, class3. Phyre2 PDB 5lc5 chain Z Region: 60 - 87 Aligned: 28 Modelled: 28 Confidence: 18.6% Identity: 21% PDB header:oxidoreductase Chain: Z: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: structure of mammalian respiratory complex i, class2 Phyre2 PDB 5ldw chain Z Region: 60 - 87 Aligned: 28 Modelled: 28 Confidence: 18.6% Identity: 21% PDB header:oxidoreductase Chain: Z: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: structure of mammalian respiratory complex i, class1 Phyre2 PDB 1rh5 chain B Region: 75 - 114 Aligned: 40 Modelled: 40 Confidence: 18.3% Identity: 8% Fold: Single transmembrane helix Superfamily: Preprotein translocase SecE subunit Family: Preprotein translocase SecE subunit Phyre2 PDB 1o4u chain A domain 2 Region: 11 - 27 Aligned: 17 Modelled: 17 Confidence: 16.0% Identity: 35% Fold: alpha/beta-Hammerhead Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like Family: NadC N-terminal domain-like Phyre2 PDB 6qj4 chain E Region: 19 - 23 Aligned: 5 Modelled: 5 Confidence: 15.8% Identity: 80% PDB header:cell cycle Chain: E: PDB Molecule:condensin complex subunit 2; PDBTitle: crystal structure of the c. thermophilum condensin ycs4-brn12 subcomplex bound to the smc4 atpase head in complex with the c-3 terminal domain of brn1 Phyre2 PDB 2l0g chain A Region: 9 - 33 Aligned: 25 Modelled: 25 Confidence: 14.1% Identity: 36% PDB header:protein binding Chain: A: PDB Molecule:dna polymerase iota; PDBTitle: solution nmr structure of ubiquitin-binding motif (ubm2) of human2 polymerase iota Phyre2 PDB 2khu chain A Region: 9 - 33 Aligned: 25 Modelled: 25 Confidence: 12.0% Identity: 36% PDB header:transferase/protein binding Chain: A: PDB Molecule:immunoglobulin g-binding protein g, dna PDBTitle: solution structure of the ubiquitin-binding motif of human2 polymerase iota Phyre2 PDB 1p4e chain A domain 1 Region: 21 - 32 Aligned: 12 Modelled: 12 Confidence: 11.9% Identity: 50% Fold: SAM domain-like Superfamily: lambda integrase-like, N-terminal domain Family: lambda integrase-like, N-terminal domain Phyre2 PDB 3mk7 chain F Region: 61 - 117 Aligned: 57 Modelled: 57 Confidence: 11.0% Identity: 12% PDB header:oxidoreductase Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p; PDBTitle: the structure of cbb3 cytochrome oxidase Phyre2 PDB 6an7 chain D Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 10.3% Identity: 4% PDB header:transport protein Chain: D: PDB Molecule:transport permease protein; PDBTitle: crystal structure of o-antigen polysaccharide abc-transporter Phyre2 PDB 2mc7 chain A Region: 57 - 77 Aligned: 21 Modelled: 21 Confidence: 9.7% Identity: 10% PDB header:membrane protein Chain: A: PDB Molecule:regulatory peptide; PDBTitle: structure of salmonella mgtr Phyre2 PDB 2ipq chain X domain 1 Region: 26 - 35 Aligned: 10 Modelled: 10 Confidence: 9.5% Identity: 40% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: STY4665 C-terminal domain-like Phyre2 PDB 1v97 chain A domain 2 Region: 6 - 32 Aligned: 21 Modelled: 27 Confidence: 9.4% Identity: 33% Fold: beta-Grasp (ubiquitin-like) Superfamily: 2Fe-2S ferredoxin-like Family: 2Fe-2S ferredoxin domains from multidomain proteins Phyre2 PDB 3g43 chain F Region: 25 - 36 Aligned: 12 Modelled: 12 Confidence: 9.2% Identity: 50% PDB header:metal binding protein Chain: F: PDB Molecule:voltage-dependent l-type calcium channel subunit alpha-1c; PDBTitle: crystal structure of the calmodulin-bound cav1.2 c-terminal regulatory2 domain dimer Phyre2 1 c3jbrE_ 2 c4hr1A_ 3 c4ymkA_ 4 c2yevB_ 5 c6c4vA_ 6 c5ldxZ_ 7 c5lc5Z_ 8 c5ldwZ_ 9 d1rh5b_ 10 d1o4ua2 11 c6qj4E_ 12 c2l0gA_ 13 c2khuA_ 14 d1p4ea1 15 c3mk7F_ 16 c6an7D_ 17 c2mc7A_ 18 d2ipqx1 19 d1v97a2 20 c3g43F_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45