1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	M	T	A	R	F	S	E	I	V	G	N	A	N	L	L	T	G	D	A	I	P	E	D	Y	A	H	D	E	E	L	T	G	P	P	Q	K	P	A	Y	A	A	K	P	A	T	P	E	E	V	A	Q	L	L	K	A	A	S
Secondary structure
SS confidence
Disorder		?																																?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	N	G	V	P	V	T	A	R	G	S	G	C	G	L	S	G	A	A	R	P	V	E	G	G	L	L	I	S	F	D	R	M	N	K	V	L	E	V	D	T	A	N	Q	V	A	V	V	Q	P	G	V	A	L	T	D	L	D	A	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	A	D	T	G	L	R	Y	T	V	Y	P	G	E	L	S	S	S	V	G	G	N	V	G	T	N	A	G	G	M	R	A	V	K	Y	G	V	A	R	H	N	V	L	G	L	Q	A	V	L	P	T	G	E	I	I	R	T	G	G	R
Secondary structure
SS confidence
Disorder														?																																											?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		M	A	K	V	S	T	G	Y	D	L	T	Q	L	I	I	G	S	E	G	T	L	A	L	V	T	E	V	I	V	K	L	H	P	R	L	D	H	N	A	S	V	L	A	P	F	A	D	F	D	Q	V	M	A	A	V	P	K	I	L	A
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	G	L	A	P	D	I	L	E	Y	I	D	N	T	S	M	A	A	L	I	S	T	Q	N	L	E	L	G	I	P	D	Q	I	R	D	S	C	E	A	Y	L	L	V	A	L	E	N	R	I	A	D	R	L	F	E	D	I	Q	T	V
Secondary structure
SS confidence
Disorder																									?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	E	M	L	M	E	L	G	A	V	D	A	Y	V	L	E	G	G	S	A	R	K	L	I	E	A	R	E	K	A	F	W	A	A	K	A	L	G	A	D	D	I	I	D	T	V	V	P	R	A	S	M	P	K	F	L	S	T	A	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	L	A	A	A	A	D	G	A	A	V	G	C	G	H	A	G	D	G	N	V	H	M	A	I	A	C	K	D	P	E	K	K	K	K	L	M	T	D	I	F	A	L	A	M	E	L	G	G	A	I	S	G	E	H	G	V	G	R	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.
Sequence		K	T	G	Y	F	L	E	L	E	D	P	V	K	I	S	L	M	R	R	I	K	Q	S	F	D	P	A	G	I	L	N	P	G	V	V	F	G	D	T
Secondary structure
SS confidence
Disorder																																				?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 3%) Alpha helix ( 36%) Beta strand ( 24%) TM helix ( 7%) (View membrane topology prediction)

Rank Aligned region

PDB 3pm9 chain A Region: 2 - 456 Aligned: 449 Modelled: 455 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative dehydrogenase (rpa1076) from2 rhodopseudomonas palustris cga009 at 2.57 a resolution Phyre2 PDB 4bc9 chain C Region: 1 - 456 Aligned: 445 Modelled: 456 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: C: PDB Molecule:alkyldihydroxyacetonephosphate synthase, peroxisomal; PDBTitle: mammalian alkyldihydroxyacetonephosphate synthase: wild-type, adduct2 with cyanoethyl Phyre2 PDB 1wve chain B Region: 1 - 455 Aligned: 455 Modelled: 455 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:4-cresol dehydrogenase [hydroxylating] PDBTitle: p-cresol methylhydroxylase: alteration of the structure of2 the flavoprotein subunit upon its binding to the3 cytochrome subunit Phyre2 PDB 5fxp chain A Region: 1 - 457 Aligned: 452 Modelled: 457 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:eugenol oxidase; PDBTitle: crystal structure of eugenol oxidase in complex with2 vanillin Phyre2 PDB 3bw7 chain A Region: 6 - 457 Aligned: 444 Modelled: 452 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:cytokinin dehydrogenase 1; PDBTitle: maize cytokinin oxidase/dehydrogenase complexed with the allenic2 cytokinin analog ha-1 Phyre2 PDB 1ahu chain B Region: 1 - 458 Aligned: 453 Modelled: 458 Confidence: 100.0% Identity: 19% PDB header:flavoenzyme Chain: B: PDB Molecule:vanillyl-alcohol oxidase; PDBTitle: structure of the octameric flavoenzyme vanillyl-alcohol2 oxidase in complex with p-cresol Phyre2 PDB 4oal chain B Region: 14 - 456 Aligned: 417 Modelled: 424 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:cytokinin dehydrogenase 4; PDBTitle: crystal structure of maize cytokinin oxidase/dehydrogenase 4 (zmcko4)2 in complex with phenylurea inhibitor cppu in alternative spacegroup Phyre2 PDB 4ml8 chain C Region: 3 - 457 Aligned: 443 Modelled: 455 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: C: PDB Molecule:cytokinin oxidase 2; PDBTitle: structure of maize cytokinin oxidase/dehydrogenase 2 (zmcko2) Phyre2 PDB 2uuv chain C Region: 2 - 452 Aligned: 406 Modelled: 418 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: C: PDB Molecule:alkyldihydroxyacetonephosphate synthase; PDBTitle: alkyldihydroxyacetonephosphate synthase in p1 Phyre2 PDB 1f0x chain A Region: 4 - 454 Aligned: 431 Modelled: 441 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:d-lactate dehydrogenase; PDBTitle: crystal structure of d-lactate dehydrogenase, a peripheral membrane2 respiratory enzyme. Phyre2 PDB 2exr chain A Region: 14 - 456 Aligned: 434 Modelled: 432 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:cytokinin dehydrogenase 7; PDBTitle: x-ray structure of cytokinin oxidase/dehydrogenase (ckx) from2 arabidopsis thaliana at5g21482 Phyre2 PDB 6c80 chain B Region: 32 - 456 Aligned: 417 Modelled: 425 Confidence: 100.0% Identity: 17% PDB header:immune system Chain: B: PDB Molecule:cytokinin oxidase luckx1.1; PDBTitle: crystal structure of a flax cytokinin oxidase Phyre2 PDB 3vte chain A Region: 3 - 457 Aligned: 434 Modelled: 434 Confidence: 100.0% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:tetrahydrocannabinolic acid synthase; PDBTitle: crystal structure of tetrahydrocannabinolic acid synthase from2 cannabis sativa Phyre2 PDB 6f74 chain B Region: 33 - 450 Aligned: 395 Modelled: 404 Confidence: 100.0% Identity: 14% PDB header:flavoprotein Chain: B: PDB Molecule:alcohol oxidase; PDBTitle: crystal structure of vao-type flavoprotein mtvao713 from2 myceliophthora thermophila c1 Phyre2 PDB 3w8w chain A Region: 2 - 457 Aligned: 434 Modelled: 448 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:putative fad-dependent oxygenase encm; PDBTitle: the crystal structure of encm Phyre2 PDB 2bvf chain A Region: 14 - 457 Aligned: 418 Modelled: 429 Confidence: 100.0% Identity: 19% PDB header:oxidase Chain: A: PDB Molecule:6-hydroxy-d-nicotine oxidase; PDBTitle: crystal structure of 6-hydoxy-d-nicotine oxidase from2 arthrobacter nicotinovorans. crystal form 3 (p1) Phyre2 PDB 4ud8 chain B Region: 4 - 455 Aligned: 432 Modelled: 438 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:fad-binding and bbe domain-containing protein; PDBTitle: atbbe15 Phyre2 PDB 3tsj chain A Region: 3 - 457 Aligned: 429 Modelled: 435 Confidence: 100.0% Identity: 16% PDB header:allergen, oxidoreductase Chain: A: PDB Molecule:pollen allergen phl p 4; PDBTitle: crystal structure of phl p 4, a grass pollen allergen with glucose2 dehydrogenase activity Phyre2 PDB 3rja chain A Region: 3 - 457 Aligned: 430 Modelled: 437 Confidence: 100.0% Identity: 13% PDB header:oxidoreductase Chain: A: PDB Molecule:carbohydrate oxidase; PDBTitle: crystal structure of carbohydrate oxidase from microdochium nivale in2 complex with substrate analogue Phyre2 PDB 6eo5 chain A Region: 2 - 457 Aligned: 429 Modelled: 435 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:ppbbe-like 1 d396n; PDBTitle: physcomitrella patens bbe-like 1 variant d396n Phyre2 1 c3pm9A_ 2 c4bc9C_ 3 c1wveB_ 4 c5fxpA_ 5 c3bw7A_ 6 c1ahuB_ 7 c4oalB_ 8 c4ml8C_ 9 c2uuvC_ 10 c1f0xA_ 11 c2exrA_ 12 c6c80B_ 13 c3vteA_ 14 c6f74B_ 15 c3w8wA_ 16 c2bvfA_ 17 c4ud8B_ 18 c3tsjA_ 19 c3rjaA_ 20 c6eo5A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169