1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	D	L	L	T	R	R	L	L	T	M	G	A	A	A	A	M	L	A	A	V	L	L	L	T	P	I	T	V	P	A	G	Y	P	G	A	V	A	P	A	T	A	A	C	P	D	A	E	V	V	F	A	R	G	R	F	E	P	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?																							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	I	G	T	V	G	N	A	F	V	S	A	L	R	S	K	V	N	K	N	V	G	V	Y	A	V	K	Y	P	A	D	N	Q	I	D	V	G	A	N	D	M	S	A	H	I	Q	S	M	A	N	S	C	P	N	T	R	L	V	P	G
Secondary structure
SS confidence
Disorder		?	?	?		?										?	?																?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	Y	S	L	G	A	A	V	T	D	V	V	L	A	V	P	T	Q	M	W	G	F	T	N	P	L	P	P	G	S	D	E	H	I	A	A	V	A	L	F	G	N	G	S	Q	W	V	G	P	I	T	N	F	S	P	A	Y	N	D	R
Secondary structure
SS confidence
Disorder															?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Sequence		T	I	E	L	C	H	G	D	D	P	V	C	H	P	A	D	P	N	T	W	E	A	N	W	P	Q	H	L	A	G	A	Y	V	S	S	G	M	V	N	Q	A	A	D	F	V	A	G	K	L	Q
Secondary structure
SS confidence
Disorder																		?		?	?	?												?		?	?													?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 30%) Alpha helix ( 38%) Beta strand ( 14%) TM helix ( 7%) (View membrane topology prediction)

Rank Aligned region

PDB 4psd chain A Region: 1 - 229 Aligned: 206 Modelled: 229 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 1cex chain A Region: 40 - 230 Aligned: 171 Modelled: 191 Confidence: 100.0% Identity: 26% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1qoz chain A Region: 45 - 229 Aligned: 174 Modelled: 185 Confidence: 100.0% Identity: 28% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 3dd5 chain F Region: 40 - 229 Aligned: 170 Modelled: 190 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 5x88 chain A Region: 35 - 229 Aligned: 175 Modelled: 195 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 1g66 chain A Region: 44 - 229 Aligned: 175 Modelled: 186 Confidence: 100.0% Identity: 25% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 2czq chain B Region: 40 - 229 Aligned: 176 Modelled: 190 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 4oyl chain C Region: 40 - 230 Aligned: 169 Modelled: 191 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 3gbs chain A Region: 34 - 229 Aligned: 176 Modelled: 196 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 3aja chain A Region: 43 - 217 Aligned: 169 Modelled: 175 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 3hc7 chain A Region: 46 - 201 Aligned: 151 Modelled: 154 Confidence: 100.0% Identity: 19% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 3g7n chain A Region: 46 - 205 Aligned: 135 Modelled: 142 Confidence: 98.2% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: crystal structure of a triacylglycerol lipase from penicillium2 expansum at 1.3 Phyre2 PDB 5xk2 chain A Region: 46 - 213 Aligned: 141 Modelled: 141 Confidence: 97.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:diacylglycerol lipase; PDBTitle: crystal structure of mono- and diacylglycerol lipase from aspergillus2 oryzae Phyre2 PDB 3uue chain A Region: 93 - 209 Aligned: 107 Modelled: 117 Confidence: 97.6% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:lip1, secretory lipase (family 3); PDBTitle: crystal structure of mono- and diacylglycerol lipase from malassezia2 globosa Phyre2 PDB 3icv chain A Region: 50 - 166 Aligned: 102 Modelled: 117 Confidence: 97.5% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:lipase b; PDBTitle: structural consequences of a circular permutation on lipase b from2 candida antartica Phyre2 PDB 1tca chain A Region: 50 - 166 Aligned: 101 Modelled: 112 Confidence: 97.5% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 6qpp chain A Region: 46 - 191 Aligned: 124 Modelled: 139 Confidence: 97.4% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: rhizomucor miehei lipase propeptide complex, native Phyre2 PDB 1uwc chain A Region: 46 - 191 Aligned: 124 Modelled: 134 Confidence: 97.2% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 5gw8 chain A Region: 99 - 164 Aligned: 56 Modelled: 66 Confidence: 97.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:hypothetical secretory lipase (family 3); PDBTitle: crystal structure of a putative dag-like lipase (mgmdl2) from2 malassezia globosa Phyre2 PDB 1tib chain A Region: 99 - 191 Aligned: 81 Modelled: 81 Confidence: 97.0% Identity: 19% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 1 c4psdA_ 2 d1cexa_ 3 d1qoza_ 4 c3dd5F_ 5 c5x88A_ 6 d1g66a_ 7 c2czqB_ 8 c4oylC_ 9 c3gbsA_ 10 c3ajaA_ 11 c3hc7A_ 12 c3g7nA_ 13 c5xk2A_ 14 c3uueA_ 15 c3icvA_ 16 d1tcaa_ 17 c6qppA_ 18 d1uwca_ 19 c5gw8A_ 20 d1tiba_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181