1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	D	A	P	R	R	R	T	A	L	A	Y	A	L	L	A	P	S	L	V	G	V	V	A	F	L	L	L	P	I	L	V	V	V	W	L	S	L	H	R	W	D	L	L	G	P	L	R	Y	V	G	L	T	N	W	R	S	V	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	D	S	G	F	A	D	S	L	V	V	T	A	V	F	V	A	I	V	V	P	A	Q	T	V	L	G	L	L	A	A	S	L	L	A	R	R	L	P	G	T	G	L	F	R	T	L	Y	V	L	P	W	I	C	A	P	L	A	I	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	M	W	R	W	I	V	A	P	T	D	G	A	I	S	T	V	L	G	H	R	I	E	W	L	T	D	P	G	L	A	L	P	V	V	S	A	V	V	V	W	T	N	V	G	Y	V	S	L	F	F	L	A	G	L	M	A	I	P	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	I	H	N	A	A	R	T	D	G	A	S	A	W	Q	R	F	W	R	I	T	L	P	M	L	R	P	T	M	F	F	V	L	V	T	G	I	I	S	A	A	Q	V	F	D	T	V	Y	A	L	T	G	G	G	P	Q	G	S	T	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
Sequence		L	V	A	H	R	I	Y	A	E	A	F	G	A	A	A	I	G	R	A	S	V	M	A	V	V	L	F	V	I	L	V	G	A	T	V	V	Q	H	L	Y	F	R	R	R	I	S	Y	E	L	T
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 4%) Alpha helix ( 78%) Beta strand ( 1%) TM helix ( 51%) (View membrane topology prediction)

Rank Aligned region

PDB 3fh6 chain F Region: 7 - 286 Aligned: 280 Modelled: 280 Confidence: 100.0% Identity: 26% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 4tqv chain I Region: 4 - 283 Aligned: 272 Modelled: 271 Confidence: 100.0% Identity: 21% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F Region: 46 - 276 Aligned: 231 Modelled: 231 Confidence: 100.0% Identity: 30% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2r6g chain G domain 1 Region: 7 - 286 Aligned: 267 Modelled: 280 Confidence: 100.0% Identity: 17% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 6 - 285 Aligned: 260 Modelled: 260 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F domain 2 Region: 53 - 276 Aligned: 224 Modelled: 224 Confidence: 100.0% Identity: 30% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C domain 1 Region: 9 - 281 Aligned: 249 Modelled: 273 Confidence: 100.0% Identity: 20% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C Region: 9 - 281 Aligned: 249 Modelled: 273 Confidence: 100.0% Identity: 20% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 3d31 chain C domain 1 Region: 14 - 278 Aligned: 244 Modelled: 265 Confidence: 100.0% Identity: 17% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 14 - 278 Aligned: 244 Modelled: 265 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 4ymu chain C Region: 52 - 283 Aligned: 211 Modelled: 217 Confidence: 100.0% Identity: 15% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 65 - 276 Aligned: 197 Modelled: 212 Confidence: 99.9% Identity: 16% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 1 Region: 8 - 43 Aligned: 36 Modelled: 36 Confidence: 94.7% Identity: 22% Fold: MalF N-terminal region-like Superfamily: MalF N-terminal region-like Family: MalF N-terminal region-like Phyre2 PDB 5kbu chain A Region: 101 - 205 Aligned: 85 Modelled: 88 Confidence: 79.2% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2hx6 chain A Region: 169 - 194 Aligned: 26 Modelled: 26 Confidence: 39.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease; PDBTitle: solution structure analysis of the phage t42 endoribonuclease regb Phyre2 PDB 2m8g chain X Region: 170 - 200 Aligned: 31 Modelled: 31 Confidence: 20.4% Identity: 23% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 4l5e chain A Region: 170 - 200 Aligned: 31 Modelled: 31 Confidence: 20.2% Identity: 13% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 1umq chain A Region: 170 - 200 Aligned: 31 Modelled: 31 Confidence: 18.5% Identity: 6% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1umq chain A Region: 170 - 200 Aligned: 31 Modelled: 31 Confidence: 18.5% Identity: 6% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1fip chain A Region: 170 - 200 Aligned: 31 Modelled: 31 Confidence: 16.2% Identity: 10% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 1 c3fh6F_ 2 c4tqvI_ 3 c2r6gF_ 4 d2r6gg1 5 c4tqvJ_ 6 d2r6gf2 7 d2onkc1 8 c2onkC_ 9 d3d31c1 10 c3d31D_ 11 c4ymuC_ 12 d3dhwa1 13 d2r6gf1 14 c5kbuA_ 15 c2hx6A_ 16 c2m8gX_ 17 c4l5eA_ 18 d1umqa_ 19 c1umqA_ 20 d1fipa_ 21 22 23 24 25 26 27 28 29 30 31 32