1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	S	P	S	R	V	S	N	T	A	V	Y	A	V	L	T	I	G	A	V	I	T	L	S	P	F	L	L	G	L	L	T	S	F	T	S	A	H	Q	F	A	T	G	T	P	L	Q	L	P	R	P	P	T	L	A	N	Y	A	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																															?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	A	D	A	G	F	R	R	A	A	V	V	T	A	L	M	T	A	V	I	L	L	G	Q	L	T	F	S	V	L	A	A	Y	A	F	A	R	L	Q	F	R	G	R	D	A	L	F	W	V	Y	V	A	T	L	M	V	P	G	T	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	V	V	P	L	Y	L	M	M	A	Q	L	G	L	R	N	T	F	W	A	L	V	L	P	F	M	F	G	S	P	Y	A	I	F	L	L	R	E	H	F	R	L	I	P	D	D	L	I	N	A	A	R	L	D	G	A	N	T	L	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	I	V	H	V	V	I	P	S	S	R	P	V	L	A	A	L	A	M	I	T	V	V	S	Q	W	N	N	F	M	W	P	L	V	I	T	S	G	H	K	W	R	V	L	T	V	A	T	A	D	L	Q	S	R	F	N	D	Q	W	T
Secondary structure
SS confidence
Disorder																																								?	?	?										?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
Sequence		L	V	M	A	A	T	T	V	A	I	V	P	L	I	A	L	F	V	T	F	Q	R	H	I	V	A	S	I	V	V	S	G	L	K
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 81%) Beta strand ( 0%) TM helix ( 52%) (View membrane topology prediction)

Rank Aligned region

PDB 2r6g chain G domain 1 Region: 3 - 274 Aligned: 269 Modelled: 272 Confidence: 100.0% Identity: 21% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 1 - 268 Aligned: 265 Modelled: 268 Confidence: 100.0% Identity: 25% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 3fh6 chain F Region: 5 - 262 Aligned: 258 Modelled: 258 Confidence: 100.0% Identity: 18% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 4tqv chain I Region: 3 - 266 Aligned: 249 Modelled: 264 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F Region: 46 - 259 Aligned: 214 Modelled: 214 Confidence: 100.0% Identity: 20% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2onk chain C Region: 5 - 262 Aligned: 237 Modelled: 241 Confidence: 100.0% Identity: 19% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 2onk chain C domain 1 Region: 5 - 262 Aligned: 237 Modelled: 241 Confidence: 100.0% Identity: 19% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 10 - 261 Aligned: 232 Modelled: 236 Confidence: 100.0% Identity: 16% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 3d31 chain C domain 1 Region: 10 - 261 Aligned: 232 Modelled: 236 Confidence: 100.0% Identity: 16% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 2 Region: 55 - 259 Aligned: 205 Modelled: 205 Confidence: 100.0% Identity: 20% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4ymu chain C Region: 63 - 266 Aligned: 200 Modelled: 204 Confidence: 99.9% Identity: 13% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 66 - 259 Aligned: 189 Modelled: 193 Confidence: 99.8% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 5kbu chain A Region: 108 - 190 Aligned: 79 Modelled: 83 Confidence: 79.7% Identity: 6% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2r6g chain F domain 1 Region: 3 - 45 Aligned: 43 Modelled: 43 Confidence: 77.8% Identity: 16% Fold: MalF N-terminal region-like Superfamily: MalF N-terminal region-like Family: MalF N-terminal region-like Phyre2 PDB 2m8g chain X Region: 155 - 185 Aligned: 31 Modelled: 31 Confidence: 50.5% Identity: 16% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 4l5e chain A Region: 155 - 185 Aligned: 31 Modelled: 31 Confidence: 46.1% Identity: 6% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 1umq chain A Region: 155 - 185 Aligned: 31 Modelled: 31 Confidence: 42.0% Identity: 6% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1umq chain A Region: 155 - 185 Aligned: 31 Modelled: 31 Confidence: 42.0% Identity: 6% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1fip chain A Region: 155 - 185 Aligned: 31 Modelled: 31 Confidence: 39.3% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 3e7l chain D Region: 155 - 185 Aligned: 31 Modelled: 31 Confidence: 37.9% Identity: 19% PDB header:transcription regulator Chain: D: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigma54 activator ntrc4's dna binding2 domain Phyre2 1 d2r6gg1 2 c4tqvJ_ 3 c3fh6F_ 4 c4tqvI_ 5 c2r6gF_ 6 c2onkC_ 7 d2onkc1 8 c3d31D_ 9 d3d31c1 10 d2r6gf2 11 c4ymuC_ 12 d3dhwa1 13 c5kbuA_ 14 d2r6gf1 15 c2m8gX_ 16 c4l5eA_ 17 d1umqa_ 18 c1umqA_ 19 d1fipa_ 20 c3e7lD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53