1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	T	A	M	R	G	D	I	R	A	A	R	E	R	D	P	A	A	P	T	A	L	E	V	I	F	C	Y	P	G	V	H	A	V	W	G	H	R	L	A	H	W	L	W	Q	R	G	A	R	L	L	A	R	A	A	A	E	F	T
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	I	L	T	G	V	D	I	H	P	G	A	V	I	G	A	R	V	F	I	D	H	A	T	G	V	V	I	G	E	T	A	E	V	G	D	D	V	T	I	Y	H	G	V	T	L	G	G	S	G	M	V	G	G	K	R	H	P	T	V
Secondary structure
SS confidence
Disorder																																																		?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	D	R	V	I	I	G	A	G	A	K	V	L	G	P	I	K	I	G	E	D	S	R	I	G	A	N	A	V	V	V	K	P	V	P	P	S	A	V	V	V	G	V	P	G	Q	V	I	G	Q	S	Q	P	S	P	G	G	P	F	D
Secondary structure
SS confidence
Disorder																																																			?	?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
Sequence		W	R	L	P	D	L	V	G	A	S	L	D	S	L	L	T	R	V	A	R	L	E	A	L	G	G	G	P	Q	A	A	G	V	I	R	P	P	E	A	G	I	W	H	G	E	D	F	S	I
Secondary structure
SS confidence
Disorder																									?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 25%) Beta strand ( 26%) TM helix ( 12%) (View membrane topology prediction)

Rank Aligned region

PDB 1t3d chain B Region: 1 - 183 Aligned: 183 Modelled: 182 Confidence: 100.0% Identity: 43% PDB header:transferase Chain: B: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of serine acetyltransferase from e.coli at 2.2a Phyre2 PDB 1t3d chain A Region: 1 - 183 Aligned: 183 Modelled: 182 Confidence: 100.0% Identity: 43% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Serine acetyltransferase Phyre2 PDB 1ssq chain A Region: 1 - 169 Aligned: 169 Modelled: 169 Confidence: 100.0% Identity: 43% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Serine acetyltransferase Phyre2 PDB 3mc4 chain A Region: 1 - 172 Aligned: 166 Modelled: 172 Confidence: 100.0% Identity: 48% PDB header:transferase Chain: A: PDB Molecule:ww/rsp5/wwp domain:bacterial transferase hexapeptide PDBTitle: crystal structure of ww/rsp5/wwp domain: bacterial transferase2 hexapeptide repeat: serine o-acetyltransferase from brucella3 melitensis Phyre2 PDB 4n6b chain B Region: 1 - 168 Aligned: 164 Modelled: 168 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: B: PDB Molecule:serine acetyltransferase apoenzyme; PDBTitle: soybean serine acetyltransferase complexed with coa Phyre2 PDB 3q1x chain A Region: 1 - 160 Aligned: 160 Modelled: 160 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of entamoeba histolytica serine acetyltransferase 12 in complex with l-serine Phyre2 PDB 3f1x chain A Region: 1 - 166 Aligned: 161 Modelled: 166 Confidence: 100.0% Identity: 41% PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: three dimensional structure of the serine acetyltransferase from2 bacteroides vulgatus, northeast structural genomics consortium target3 bvr62. Phyre2 PDB 4e8l chain C Region: 68 - 205 Aligned: 138 Modelled: 138 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: C: PDB Molecule:virginiamycin a acetyltransferase; PDBTitle: crystal structure of streptogramin group a antibiotic2 acetyltransferase vata from staphylococcus aureus Phyre2 PDB 1krr chain A Region: 66 - 182 Aligned: 117 Modelled: 117 Confidence: 100.0% Identity: 28% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 1ocx chain A Region: 32 - 170 Aligned: 139 Modelled: 139 Confidence: 100.0% Identity: 22% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 1xat chain A Region: 60 - 204 Aligned: 145 Modelled: 145 Confidence: 100.0% Identity: 21% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 5jxx chain C Region: 65 - 204 Aligned: 138 Modelled: 140 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o- PDBTitle: crystal structure of udp-n-acetylglucosamine o-acyltransferase (lpxa)2 from moraxella catarrhalis rh4. Phyre2 PDB 2iu9 chain C Region: 60 - 202 Aligned: 138 Modelled: 141 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: C: PDB Molecule:udp-3-o-[3-hydroxymyristoyl] glucosamine PDBTitle: chlamydia trachomatis lpxd with 100mm udpglcnac (complex ii) Phyre2 PDB 5dg3 chain D Region: 66 - 204 Aligned: 137 Modelled: 139 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: D: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o- PDBTitle: structure of pseudomonas aeruginosa lpxa in complex with udp-3-o-(r-3-2 hydroxydecanoyl)-glcnac Phyre2 PDB 3r0s chain A Region: 66 - 205 Aligned: 138 Modelled: 140 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o- PDBTitle: udp-n-acetylglucosamine acyltransferase from campylobacter jejuni Phyre2 PDB 1mr7 chain A Region: 66 - 205 Aligned: 137 Modelled: 140 Confidence: 100.0% Identity: 24% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 2ic7 chain A Region: 65 - 172 Aligned: 108 Modelled: 108 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:maltose transacetylase; PDBTitle: crystal structure of maltose transacetylase from geobacillus2 kaustophilus Phyre2 PDB 6mfk chain A Region: 68 - 204 Aligned: 136 Modelled: 137 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:chloramphenicol acetyltransferase; PDBTitle: crystal structure of chloramphenicol acetyltransferase from2 elizabethkingia anophelis Phyre2 PDB 4r36 chain A Region: 66 - 204 Aligned: 137 Modelled: 139 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:putative acyl-[acyl-carrier-protein]--udp-n- PDBTitle: crystal structure analysis of lpxa, a udp-n-acetylglucosamine2 acyltransferase from bacteroides fragilis 9343 Phyre2 PDB 1j2z chain A Region: 66 - 204 Aligned: 137 Modelled: 139 Confidence: 99.9% Identity: 32% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: UDP N-acetylglucosamine acyltransferase Phyre2 1 c1t3dB_ 2 d1t3da_ 3 d1ssqa_ 4 c3mc4A_ 5 c4n6bB_ 6 c3q1xA_ 7 c3f1xA_ 8 c4e8lC_ 9 d1krra_ 10 d1ocxa_ 11 d1xata_ 12 c5jxxC_ 13 c2iu9C_ 14 c5dg3D_ 15 c3r0sA_ 16 d1mr7a_ 17 c2ic7A_ 18 c6mfkA_ 19 c4r36A_ 20 d1j2za_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99