Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD2356c_(PPE40)_2637698_2639545
DateMon Aug 5 13:25:51 BST 2019
Unique Job ID43f6aab8cb29e0c2
SequenceVVNFSVLPPE ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:62.092 Y:71.855 Z:71.508
Model (left) based on template c5xfsB_
Top template information
PDB header:protein transport
Chain: B: PDB Molecule:ppe family protein ppe15;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis
Confidence and coverage
Confidence:100.0% Coverage: 28%
172 residues ( 28% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Warning: 70% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c5xfsB_



100.0 53
PDB header:protein transport
Chain: B: PDB Molecule:ppe family protein ppe15;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis
2d2g38b1



100.0 31
Fold:Ferritin-like
Superfamily:PE/PPE dimer-like
Family:PPE
3c2g38B_



100.0 31
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:ppe family protein;
PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis
4c4xy3A_



100.0 18
PDB header:protein transport
Chain: A: PDB Molecule:esx-1 secretion-associated protein espb;
PDBTitle: structure of esx-1 secreted protein espb
5c4wj2A_



99.3 17
PDB header:unknown function
Chain: A: PDB Molecule:antigen mtb48;
PDBTitle: mycobacterial protein
6c2vs0B_



98.2 11
PDB header:cell invasion
Chain: B: PDB Molecule:virulence factor esxa;
PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa
7c3gvmA_



98.0 10
PDB header:viral protein
Chain: A: PDB Molecule:putative uncharacterized protein sag1039;
PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae
8c4iogD_



98.0 19
PDB header:unknown function
Chain: D: PDB Molecule:secreted protein esxb;
PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne
9c3zbhC_



98.0 16
PDB header:unknown function
Chain: C: PDB Molecule:esxa;
PDBTitle: geobacillus thermodenitrificans esxa crystal form i
10d1wa8a1



97.6 16
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
11c4lwsA_



96.7 14
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
12c4lwsB_



96.6 13
PDB header:unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
13d1wa8b1



96.5 17
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
14c4i0xA_



95.8 23
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:esat-6-like protein mab_3112;
PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex
15c2kg7B_



94.3 20
PDB header:unknown function
Chain: B: PDB Molecule:esat-6-like protein esxh;
PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288
16c4i0xJ_



91.9 28
PDB header:structural genomics, unknown function
Chain: J: PDB Molecule:esat-6-like protein mab_3113;
PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex
17d1ui5a2



75.3 30
Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
18c2ahmG_



38.9 22
PDB header:viral protein, replication
Chain: G: PDB Molecule:replicase polyprotein 1ab, heavy chain;
PDBTitle: crystal structure of sars-cov super complex of non-structural2 proteins: the hexadecamer
19c2iu1A_



37.4 39
PDB header:transcription
Chain: A: PDB Molecule:eukaryotic translation initiation factor 5;
PDBTitle: crystal structure of eif5 c-terminal domain
20d1xkna_



36.5 14
Fold:Pentein, beta/alpha-propeller
Superfamily:Pentein
Family:Porphyromonas-type peptidylarginine deiminase
21c3ub0D_



not modelled 31.0 12
PDB header:replication
Chain: D: PDB Molecule:non-structural protein 6, nsp6,;
PDBTitle: crystal structure of the nonstructural protein 7 and 8 complex of2 feline coronavirus
22c2fulE_



not modelled 28.8 33
PDB header:translation
Chain: E: PDB Molecule:eukaryotic translation initiation factor 5;
PDBTitle: crystal structure of the c-terminal domain of s. cerevisiae eif5
23c2l5bA_



not modelled 26.4 53
PDB header:apoptosis
Chain: A: PDB Molecule:activator of apoptosis harakiri;
PDBTitle: solution structure of the transmembrane domain of bcl-2 member2 harakiri in micelles
24c5frgA_



not modelled 24.5 75
PDB header:protein binding
Chain: A: PDB Molecule:formin-binding protein 1-like;
PDBTitle: the nmr structure of the cdc42-interacting region of toca1
25c4wgiA_



not modelled 22.8 16
PDB header:apoptosis/inhibitor
Chain: A: PDB Molecule:maltose-binding periplasmic protein,induced myeloid
PDBTitle: a single diastereomer of a macrolactam core binds specifically to2 myeloid cell leukemia 1 (mcl1)
26c3fnbB_



not modelled 22.6 12
PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159
27c1paqA_



not modelled 22.4 15
PDB header:translation
Chain: A: PDB Molecule:translation initiation factor eif-2b epsilon
PDBTitle: crystal structure of the catalytic fragment of eukaryotic2 initiation factor 2b epsilon
28d1paqa_



not modelled 22.4 15
Fold:alpha-alpha superhelix
Superfamily:ARM repeat
Family:MIF4G domain-like
29c3h6pB_



not modelled 21.8 33
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:esat-6 like protein esxs;
PDBTitle: crystal structure of rv3019c-rv3020c from mycobacterium tuberculosis
30c2kg7A_



not modelled 21.1 37
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein esxg (pe family protein);
PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288
31c1bkvA_



not modelled 19.9 44
PDB header:structural protein
Chain: A: PDB Molecule:t3-785;
PDBTitle: collagen
32c1bkvC_



not modelled 18.6 44
PDB header:structural protein
Chain: C: PDB Molecule:t3-785;
PDBTitle: collagen
33c1bkvB_



not modelled 18.6 44
PDB header:structural protein
Chain: B: PDB Molecule:t3-785;
PDBTitle: collagen
34c3juiA_



not modelled 17.5 23
PDB header:translation
Chain: A: PDB Molecule:translation initiation factor eif-2b subunit epsilon;
PDBTitle: crystal structure of the c-terminal domain of human translation2 initiation factor eif2b epsilon subunit
35c2ke4A_



not modelled 16.8 75
PDB header:membrane protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4
36c4n91A_



not modelled 16.1 15
PDB header:transport protein
Chain: A: PDB Molecule:trap dicarboxylate transporter, dctp subunit;
PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 anaerococcus prevotii dsm 20548 (apre_1383), target efi-510023, with3 bound alpha/beta d-glucuronate
37c3jywF_



not modelled 15.9 54
PDB header:ribosome
Chain: F: PDB Molecule:60s ribosomal protein l7(a);
PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution
38c3r5zB_



not modelled 15.6 9
PDB header:unknown function
Chain: B: PDB Molecule:putative uncharacterized protein;
PDBTitle: structure of a deazaflavin-dependent reductase from nocardia2 farcinica, with co-factor f420
39c3zfsA_



not modelled 13.9 15
PDB header:oxidoreductase
Chain: A: PDB Molecule:f420-reducing hydrogenase, subunit alpha;
PDBTitle: cryo-em structure of the f420-reducing nife-hydrogenase from a2 methanogenic archaeon with bound substrate
40c4y9iA_



not modelled 13.9 15
PDB header:oxidoreductase
Chain: A: PDB Molecule:mycobacterium tuberculosis paralogous family 11;
PDBTitle: structure of f420-h2 dependent reductase (fdr-a) msmeg_2027
41c2l5aA_



not modelled 12.6 19
PDB header:nuclear protein
Chain: A: PDB Molecule:histone h3-like centromeric protein cse4, protein scm3,
PDBTitle: structural basis for recognition of centromere specific histone h32 variant by nonhistone scm3
42c2kp7A_



not modelled 12.6 17
PDB header:hydrolase
Chain: A: PDB Molecule:crossover junction endonuclease mus81;
PDBTitle: solution nmr structure of the mus81 n-terminal hhh.2 northeast structural genomics consortium target mmt1a
43c5yysC_



not modelled 12.5 17
PDB header:transferase
Chain: C: PDB Molecule:l-fucokinase, l-fucose-1-p guanylyltransferase;
PDBTitle: cryo-em structure of l-fucokinase, gdp-fucose pyrophosphorylase (fkp)2 in bacteroides fragilis
44c4oo3A_



not modelled 12.4 10
PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of a putative oxidoreductase (parmer_00841) from2 parabacteroides merdae atcc 43184 at 2.23 a resolution
45c6epiC_



not modelled 12.4 13
PDB header:toxin
Chain: C: PDB Molecule:epsilon_1 antitoxin;
PDBTitle: structure of the epsilon_1 / zeta_1 antitoxin / toxin system from2 neisseria gonorrhoeae in complex with unam-4p.
46c4deyB_



not modelled 12.2 18
PDB header:transport protein
Chain: B: PDB Molecule:voltage-dependent l-type calcium channel subunit alpha-1c;
PDBTitle: crystal structure of the voltage dependent calcium channel beta-22 subunit in complex with the cav1.2 i-ii linker.
47c3mveB_



not modelled 11.4 17
PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
48c3j3bF_



not modelled 10.7 31
PDB header:ribosome
Chain: F: PDB Molecule:60s ribosomal protein l7;
PDBTitle: structure of the human 60s ribosomal proteins
49c3trhI_



not modelled 10.7 10
PDB header:lyase
Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase
PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii
50c5djsA_



not modelled 10.6 20
PDB header:transferase
Chain: A: PDB Molecule:tetratricopeptide tpr_2 repeat protein;
PDBTitle: thermobaculum terrenum o-glcnac transferase mutant - k341m
51c3j21Y_



not modelled 10.6 25
PDB header:ribosome
Chain: Y: PDB Molecule:50s ribosomal protein l30p;
PDBTitle: promiscuous behavior of proteins in archaeal ribosomes revealed by2 cryo-em: implications for evolution of eukaryotic ribosomes (50s3 ribosomal proteins)
52c3h96B_



not modelled 10.3 6
PDB header:flavoprotein
Chain: B: PDB Molecule:f420-h2 dependent reductase a;
PDBTitle: msmeg_3358 f420 reductase
53c3r5wO_



not modelled 10.1 15
PDB header:oxidoreductase
Chain: O: PDB Molecule:deazaflavin-dependent nitroreductase;
PDBTitle: structure of ddn, the deazaflavin-dependent nitroreductase from2 mycobacterium tuberculosis involved in bioreductive activation of pa-3 824, with co-factor f420
54c2lyyB_



not modelled 9.8 13
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: nmr structure of the protein nb7890a from shewanella sp
55c6hu9u_



not modelled 9.7 18
PDB header:oxidoreductase/electron transport
Chain: U: PDB Molecule:cytochrome b-c1 complex subunit 10;
PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae
56c2kwuA_



not modelled 9.7 38
PDB header:protein binding/signaling protein
Chain: A: PDB Molecule:dna polymerase iota;
PDBTitle: solution structure of ubm2 of murine polymerase iota in complex with2 ubiquitin
57c3j39F_



not modelled 9.6 38
PDB header:ribosome
Chain: F: PDB Molecule:60s ribosomal protein l7;
PDBTitle: structure of the d. melanogaster 60s ribosomal proteins
58c4grdA_



not modelled 9.6 19
PDB header:lyase,isomerase
Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit;
PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase2 catalytic subunit from burkholderia cenocepacia j2315
59c5hl8B_



not modelled 9.5 24
PDB header:protein transport
Chain: B: PDB Molecule:type ii secretion system protein l;
PDBTitle: 1.93 angstrom resolution crystal structure of a pullulanase-specific2 type ii secretion system integral cytoplasmic membrane protein gspl3 (c-terminal fragment; residues 309-397) from klebsiella pneumoniae4 subsp. pneumoniae ntuh-k2044
60c5lzkB_



not modelled 9.2 9
PDB header:structural genomics
Chain: B: PDB Molecule:protein fam83b;
PDBTitle: structure of the domain of unknown function duf1669 from human fam83b
61c3pe3D_



not modelled 9.2 18
PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate
62c3r5yC_



not modelled 9.1 15
PDB header:unknown function
Chain: C: PDB Molecule:putative uncharacterized protein;
PDBTitle: structure of a deazaflavin-dependent nitroreductase from nocardia2 farcinica, with co-factor f420
63c4i6jB_



not modelled 8.9 22
PDB header:transcription
Chain: B: PDB Molecule:f-box/lrr-repeat protein 3;
PDBTitle: a ubiquitin ligase-substrate complex
64c4oanB_



not modelled 8.9 14
PDB header:membrane protein/protein transport
Chain: B: PDB Molecule:trap dicarboxylate transporter dctp subunit;
PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 rhodopseudomonas palustris haa2 (rpb_2686), target efi-510221, with3 density modeled as (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2-4 acetolactate)
65c2zzxD_



not modelled 8.7 14
PDB header:transport protein
Chain: D: PDB Molecule:abc transporter, solute-binding protein;
PDBTitle: crystal structure of a periplasmic substrate binding protein in2 complex with lactate
66c5vmoB_



not modelled 8.6 50
PDB header:viral protein/apoptosis
Chain: B: PDB Molecule:bcl-2 interacting mediator of cell death;
PDBTitle: crystal structure of grouper iridovirus giv66:bim complex
67d1vqow1



not modelled 8.5 19
Fold:Ribosomal protein L30p/L7e
Superfamily:Ribosomal protein L30p/L7e
Family:Ribosomal protein L30p/L7e
68c2xgvA_



not modelled 8.5 14
PDB header:viral protein
Chain: A: PDB Molecule:psiv capsid n-terminal domain;
PDBTitle: structure of the n-terminal domain of capsid protein from2 rabbit endogenous lentivirus (relik)
69c3qthA_



not modelled 8.5 9
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a dinb-like protein (cps_3021) from colwellia2 psychrerythraea 34h at 2.20 a resolution
70c2vsnB_



not modelled 8.4 14
PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
71c3n6xA_



not modelled 8.4 13
PDB header:ligase
Chain: A: PDB Molecule:putative glutathionylspermidine synthase;
PDBTitle: crystal structure of a putative glutathionylspermidine synthase2 (mfla_0391) from methylobacillus flagellatus kt at 2.35 a resolution
72d2fgga1



not modelled 8.4 40
Fold:dsRBD-like
Superfamily:Rv2632c-like
Family:Rv2632c-like
73c6ghrF_



not modelled 8.3 53
PDB header:photosynthesis
Chain: F: PDB Molecule:cp12 polypeptide;
PDBTitle: cyanobacterial gapdh with full-length cp12
74c5i4rA_



not modelled 8.3 43
PDB header:toxin/antitoxin
Chain: A: PDB Molecule:contact-dependent inhibitor a;
PDBTitle: contact-dependent inhibition system from escherichia coli nc101 -2 ternary cdia/cdii/ef-tu complex (trypsin-modified)
75c3zf7w_



not modelled 8.2 25
PDB header:ribosome
Chain: W: PDB Molecule:60s ribosomal protein l23, putative;
PDBTitle: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
76c3izce_



not modelled 8.2 19
PDB header:ribosome
Chain: E: PDB Molecule:60s ribosomal protein rpl11 (l5p);
PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome
77c2i3fA_



not modelled 8.1 13
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:glycolipid transfer-like protein;
PDBTitle: crystal structure of a glycolipid transfer-like protein from galdieria2 sulphuraria
78c5ec0A_



not modelled 7.9 33
PDB header:structural protein
Chain: A: PDB Molecule:alp7a;
PDBTitle: crystal structure of actin-like protein alp7a
79c2wybA_



not modelled 7.8 16
PDB header:hydrolase
Chain: A: PDB Molecule:acyl-homoserine lactone acylase pvdq subunit
PDBTitle: the quorum quenching n-acyl homoserine lactone acylase pvdq2 with a covalently bound dodecanoic acid
80d1luaa2



not modelled 7.7 29
Fold:Aminoacid dehydrogenase-like, N-terminal domain
Superfamily:Aminoacid dehydrogenase-like, N-terminal domain
Family:Methylene-tetrahydromethanopterin dehydrogenase
81c5kdiA_



not modelled 7.6 15
PDB header:lipid transport
Chain: A: PDB Molecule:pleckstrin homology domain-containing family a member 8;
PDBTitle: how fapp2 selects simple glycosphingolipids using the gltp-fold
82c4mnpA_



not modelled 7.6 14
PDB header:sugar binding protein
Chain: A: PDB Molecule:n-acetylneuraminate-binding protein;
PDBTitle: structure of the sialic acid binding protein from fusobacterium2 nucleatum subsp. nucleatum atcc 25586
83c4wpyA_



not modelled 7.6 20
PDB header:de novo protein
Chain: A: PDB Molecule:protein dl-rv1738;
PDBTitle: racemic crystal structure of rv1738 from mycobacterium tuberculosis2 (form-ii)
84c6ansD_



not modelled 7.5 16
PDB header:unknown function
Chain: D: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative uncharacterized protein from2 burkholderia cenocepacia
85c1gk9A_



not modelled 7.4 16
PDB header:antibiotic resistance
Chain: A: PDB Molecule:penicillin g acylase alpha subunit;
PDBTitle: crystal structures of penicillin acylase enzyme-substrate2 complexes: structural insights into the catalytic mechanism
86c1d0rA_



not modelled 7.1 40
PDB header:hormone/growth factor
Chain: A: PDB Molecule:glucagon-like peptide-1-(7-36)-amide;
PDBTitle: solution structure of glucagon-like peptide-1-(7-36)-amide in2 trifluoroethanol/water
87d2apla1



not modelled 7.1 10
Fold:PG0816-like
Superfamily:PG0816-like
Family:PG0816-like
88c2hueB_



not modelled 7.0 23
PDB header:dna binding protein
Chain: B: PDB Molecule:histone h3;
PDBTitle: structure of the h3-h4 chaperone asf1 bound to histones h3 and h4
89d1kx5a_



not modelled 6.9 23
Fold:Histone-fold
Superfamily:Histone-fold
Family:Nucleosome core histones
90c2vh3B_



not modelled 6.9 44
PDB header:unknown function
Chain: B: PDB Molecule:ranasmurfin;
PDBTitle: ranasmurfin
91c6e0cA_



not modelled 6.8 29
PDB header:nuclear protein
Chain: A: PDB Molecule:histone h3-like centromeric protein a;
PDBTitle: cryo-em structure of the cenp-a nucleosome (w601) in complex with a2 single chain antibody fragment
92c1jrjA_



not modelled 6.7 27
PDB header:hormone/growth factor
Chain: A: PDB Molecule:exendin-4;
PDBTitle: solution structure of exendin-4 in 30-vol% trifluoroethanol
93c6bc8B_



not modelled 6.7 22
PDB header:replication
Chain: B: PDB Molecule:dna polymerase zeta catalytic subunit;
PDBTitle: crystal structure of rev7-r124a/rev3-rbm2 (residues 1988-2014) complex
94c6bcdB_



not modelled 6.7 22
PDB header:replication
Chain: B: PDB Molecule:dna polymerase zeta catalytic subunit;
PDBTitle: crystal structure of rev7-k44a/r124a/a135d in complex with rev3-rbm22 (residues 1988-2014)
95c6ekmB_



not modelled 6.7 22
PDB header:replication
Chain: B: PDB Molecule:dna polymerase zeta catalytic subunit;
PDBTitle: crystal structure of mammalian rev7 in complex with human rev3 second2 binding site
96c6bi7D_



not modelled 6.7 22
PDB header:replication
Chain: D: PDB Molecule:dna polymerase zeta catalytic subunit;
PDBTitle: crystal structure of rev7-wt/rev3 as a monomer under high-salt2 conditions
97c3a9rA_



not modelled 6.7 19
PDB header:isomerase
Chain: A: PDB Molecule:d-arabinose isomerase;
PDBTitle: x-ray structures of bacillus pallidus d-arabinose2 isomerasecomplex with (4r)-2-methylpentane-2,4-diol
98c6o9l6_



not modelled 6.7 40
PDB header:transcription/dna
Chain: 6: PDB Molecule:general transcription factor iih subunit 2;
PDBTitle: human holo-pic in the closed state
99c4gyxC_



not modelled 6.5 54
PDB header:structural protein, blood clotting
Chain: C: PDB Molecule:type iii collagen fragment in a host peptide stabilized by
PDBTitle: the von willebrand factor a3 domain binding region of type iii2 collagen stabilized by the cysteine knot

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