1

.

.

.

.

.

.

.

.

10

.

.

.

.

.

.

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.

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20

.

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.

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.

30

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.

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40

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.

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.

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50

.

.

.

.

.

.

.

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.

60

Sequence

M

S

L

V

S

V

A

P

E

L

V

V

T

A

V

P

D

V

A

R

I

G

S

S

I

G

A

P

D

T

A

A

A

A

R

P

T

T

S

V

L

A

A

G

A

D

E

V

S

A

D

V

V

A

L

F

G

W

V

A

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

Sequence

R

Secondary structure

SS confidence

Disorder

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 38%) Alpha helix ( 95%) Beta strand ( 0%)

Rank Aligned region

PDB 5xfs chain A Region: 7 - 61 Aligned: 54 Modelled: 55 Confidence: 99.9% Identity: 41% PDB header:protein transport Chain: A: PDB Molecule:pe family protein pe8; PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis Phyre2 PDB 2g38 chain A domain 1 Region: 8 - 61 Aligned: 53 Modelled: 54 Confidence: 99.9% Identity: 32% Fold: Ferritin-like Superfamily: PE/PPE dimer-like Family: PE Phyre2 PDB 2g38 chain A Region: 8 - 61 Aligned: 53 Modelled: 54 Confidence: 99.9% Identity: 32% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:pe family protein; PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis Phyre2 PDB 2rff chain A Region: 55 - 61 Aligned: 7 Modelled: 7 Confidence: 10.0% Identity: 57% PDB header:transferase Chain: A: PDB Molecule:putative nucleotidyltransferase; PDBTitle: crystal structure of a putative nucleotidyltransferase (np_343093.1)2 from sulfolobus solfataricus at 1.40 a resolution Phyre2 PDB 3eab chain K Region: 38 - 55 Aligned: 18 Modelled: 18 Confidence: 9.8% Identity: 44% PDB header:cell cycle Chain: K: PDB Molecule:chmp1b; PDBTitle: crystal structure of spastin mit in complex with escrt iii Phyre2 PDB 1no5 chain A Region: 55 - 61 Aligned: 7 Modelled: 7 Confidence: 9.7% Identity: 29% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Catalytic subunit of bi-partite nucleotidyltransferase Phyre2 PDB 1ylq chain A domain 1 Region: 55 - 61 Aligned: 7 Modelled: 7 Confidence: 7.2% Identity: 43% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Catalytic subunit of bi-partite nucleotidyltransferase Phyre2 PDB 1wot chain A Region: 55 - 61 Aligned: 7 Modelled: 7 Confidence: 7.0% Identity: 71% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Catalytic subunit of bi-partite nucleotidyltransferase Phyre2 PDB 2f05 chain A domain 1 Region: 46 - 59 Aligned: 14 Modelled: 14 Confidence: 6.9% Identity: 36% Fold: PAH2 domain Superfamily: PAH2 domain Family: PAH2 domain Phyre2 PDB 5yep chain A Region: 55 - 61 Aligned: 7 Modelled: 7 Confidence: 6.4% Identity: 43% PDB header:antitoxin/toxin Chain: A: PDB Molecule:toxin-antitoxin system antidote mnt family; PDBTitle: crystal structure of so_3166-so_3165 from shewanella oneidensis Phyre2 1 c5xfsA_ 2 d2g38a1 3 c2g38A_ 4 c2rffA_ 5 c3eabK_ 6 d1no5a_ 7 d1ylqa1 8 d1wota_ 9 d2f05a1 10 c5yepA_