1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	G	E	T	T	R	L	T	E	P	Q	L	R	E	L	A	A	R	G	A	A	E	L	D	G	A	T	A	T	D	M	L	R	W	T	D	E	T	F	G	D	I	G	G	A	G	G	G	V	S	G	H	R	G	W	T	T	C	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?		?																																								?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	V	V	A	S	N	M	A	D	A	V	L	V	D	L	A	A	K	V	R	P	G	V	P	V	I	F	L	D	T	G	Y	H	F	V	E	T	I	G	T	R	D	A	I	E	S	V	Y	D	V	R	V	L	N	V	T	P	E	H	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	A	E	Q	D	E	L	L	G	K	D	L	F	A	R	N	P	H	E	C	C	R	L	R	K	V	V	P	L	G	K	T	L	R	G	Y	S	A	W	V	T	G	L	R	R	V	D	A	P	T	R	A	N	A	P	L	V	S	F	D
Secondary structure
SS confidence
Disorder																																																	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	T	F	K	L	V	K	V	N	P	L	A	A	W	T	D	Q	D	V	Q	E	Y	I	A	D	N	D	V	L	V	N	P	L	V	R	E	G	Y	P	S	I	G	C	A	P	C	T	A	K	P	A	E	G	A	D	P	R	S	G	R
Secondary structure
SS confidence
Disorder																																																				?	?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.
Sequence		W	Q	G	L	A	K	T	E	C	G	L	H	A	S
Secondary structure
SS confidence
Disorder											?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 10%) Alpha helix ( 47%) Beta strand ( 12%)

Rank Aligned region

PDB 2oq2 chain B Region: 14 - 254 Aligned: 218 Modelled: 225 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: crystal structure of yeast paps reductase with pap, a product complex Phyre2 PDB 2o8v chain A Region: 17 - 253 Aligned: 205 Modelled: 207 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: paps reductase in a covalent complex with thioredoxin c35a Phyre2 PDB 2goy chain C Region: 17 - 244 Aligned: 212 Modelled: 213 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase Chain: C: PDB Molecule:adenosine phosphosulfate reductase; PDBTitle: crystal structure of assimilatory adenosine 5'-2 phosphosulfate reductase with bound aps Phyre2 PDB 4bwv chain B Region: 17 - 240 Aligned: 205 Modelled: 208 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: B: PDB Molecule:phosphoadenosine-phosphosulphate reductase; PDBTitle: structure of adenosine 5-prime-phosphosulfate reductase apr-b from2 physcomitrella patens Phyre2 PDB 1sur chain A Region: 9 - 225 Aligned: 200 Modelled: 200 Confidence: 100.0% Identity: 31% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: PAPS reductase-like Phyre2 PDB 3g59 chain A Region: 11 - 240 Aligned: 211 Modelled: 217 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:fmn adenylyltransferase; PDBTitle: crystal structure of candida glabrata fmn adenylyltransferase in2 complex with atp Phyre2 PDB 2wsi chain A Region: 16 - 229 Aligned: 192 Modelled: 198 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:fad synthetase; PDBTitle: crystal structure of yeast fad synthetase (fad1) in complex2 with fad Phyre2 PDB 1zun chain A Region: 29 - 214 Aligned: 170 Modelled: 170 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:sulfate adenylyltransferase subunit 2; PDBTitle: crystal structure of a gtp-regulated atp sulfurylase2 heterodimer from pseudomonas syringae Phyre2 PDB 1zun chain A domain 1 Region: 29 - 214 Aligned: 170 Modelled: 170 Confidence: 100.0% Identity: 19% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: PAPS reductase-like Phyre2 PDB 3bl5 chain E Region: 57 - 227 Aligned: 166 Modelled: 166 Confidence: 99.8% Identity: 13% PDB header:hydrolase Chain: E: PDB Molecule:queuosine biosynthesis protein quec; PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis Phyre2 PDB 3vrh chain A Region: 33 - 212 Aligned: 167 Modelled: 180 Confidence: 99.7% Identity: 17% PDB header:rna binding protein Chain: A: PDB Molecule:putative uncharacterized protein ph0300; PDBTitle: crystal structure of ph0300 Phyre2 PDB 5gha chain C Region: 30 - 212 Aligned: 167 Modelled: 183 Confidence: 99.6% Identity: 14% PDB header:transferase/transport protein Chain: C: PDB Molecule:sulfur transferase ttua; PDBTitle: sulfur transferase ttua in complex with sulfur carrier ttub Phyre2 PDB 1ni5 chain A domain 1 Region: 56 - 210 Aligned: 144 Modelled: 155 Confidence: 99.6% Identity: 13% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: PP-loop ATPase Phyre2 PDB 1wy5 chain A domain 1 Region: 54 - 220 Aligned: 160 Modelled: 167 Confidence: 99.5% Identity: 13% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: PP-loop ATPase Phyre2 PDB 3a2k chain B Region: 54 - 210 Aligned: 150 Modelled: 157 Confidence: 99.5% Identity: 9% PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna Phyre2 PDB 1k92 chain A domain 1 Region: 54 - 216 Aligned: 161 Modelled: 163 Confidence: 99.5% Identity: 9% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1ni5 chain A Region: 56 - 211 Aligned: 145 Modelled: 156 Confidence: 99.5% Identity: 12% PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli Phyre2 PDB 2dpl chain A Region: 30 - 224 Aligned: 162 Modelled: 165 Confidence: 99.4% Identity: 16% PDB header:ligase Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b; PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3 Phyre2 PDB 2e21 chain A Region: 54 - 210 Aligned: 150 Modelled: 157 Confidence: 99.4% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. Phyre2 PDB 1j20 chain A domain 1 Region: 58 - 211 Aligned: 151 Modelled: 154 Confidence: 99.4% Identity: 9% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 1 c2oq2B_ 2 c2o8vA_ 3 c2goyC_ 4 c4bwvB_ 5 d1sura_ 6 c3g59A_ 7 c2wsiA_ 8 c1zunA_ 9 d1zuna1 10 c3bl5E_ 11 c3vrhA_ 12 c5ghaC_ 13 d1ni5a1 14 d1wy5a1 15 c3a2kB_ 16 d1k92a1 17 c1ni5A_ 18 c2dplA_ 19 c2e21A_ 20 d1j20a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118