1

.

.

.

.

.

.

.

.

10

.

.

.

.

.

.

.

.

.

20

.

.

.

.

.

.

.

.

.

30

.

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

Sequence

M

S

F

L

I

A

S

P

E

A

L

A

A

T

A

T

Y

L

T

G

I

G

S

A

I

S

A

A

N

A

V

A

A

A

P

T

T

E

I

L

A

A

G

T

D

E

V

S

T

A

I

S

A

L

F

G

A

H

A

Q

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

.

.

.

90

.

.

.

.

.

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.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

Sequence

A

Y

Q

A

L

S

A

H

V

A

A

F

H

D

Q

F

V

H

T

L

T

A

G

A

G

S

Y

M

A

A

E

A

A

A

A

S

P

L

Q

A

L

Q

L

E

L

L

N

A

I

N

A

P

T

L

A

L

L

G

R

P

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

.

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

Sequence

L

I

G

D

G

T

D

A

A

P

G

S

G

G

A

G

G

A

G

G

I

L

I

G

N

G

G

T

G

G

A

S

D

L

A

G

T

G

R

G

G

V

G

G

A

G

G

A

G

G

L

F

G

I

G

G

A

G

G

G

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

190

.

.

.

.

.

.

.

.

.

200

.

.

.

.

.

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

.

230

.

.

.

.

.

.

.

.

.

240

Sequence

C

G

S

A

V

A

I

G

G

D

G

G

A

G

G

A

G

G

V

F

S

G

G

G

A

G

G

A

G

D

A

I

G

G

S

G

G

A

G

G

T

G

G

L

L

G

G

G

G

G

A

G

G

A

G

G

A

G

G

N

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

250

.

.

.

.

.

.

.

.

.

260

.

.

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

.

.

.

290

.

.

.

.

.

.

.

.

.

300

Sequence

G

G

G

A

S

N

S

A

S

I

G

G

D

G

G

S

G

G

A

G

G

M

L

Y

G

A

G

G

V

G

G

N

G

G

A

A

V

A

I

G

G

D

G

G

A

G

G

R

A

G

A

I

G

N

G

G

D

G

G

N

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

310

.

.

.

.

.

.

.

.

.

320

.

.

.

.

.

.

.

.

.

330

.

.

.

.

.

.

.

.

.

340

.

.

.

.

.

.

.

.

.

350

.

.

.

.

.

.

.

.

.

360

Sequence

G

G

T

S

N

T

P

G

G

S

G

G

D

G

G

N

G

G

N

A

G

L

I

G

N

G

G

N

G

G

N

A

E

I

V

I

S

G

G

S

V

A

G

T

G

G

N

G

G

L

L

L

G

F

N

G

T

N

G

L

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

Sequence

P

Secondary structure

SS confidence

Disorder

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 61%) Alpha helix ( 30%) Beta strand ( 7%)

Rank Aligned region

PDB 2g38 chain A domain 1 Region: 8 - 84 Aligned: 77 Modelled: 77 Confidence: 99.9% Identity: 31% Fold: Ferritin-like Superfamily: PE/PPE dimer-like Family: PE Phyre2 PDB 2g38 chain A Region: 8 - 84 Aligned: 77 Modelled: 77 Confidence: 99.9% Identity: 31% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:pe family protein; PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis Phyre2 PDB 5xfs chain A Region: 7 - 84 Aligned: 78 Modelled: 78 Confidence: 99.9% Identity: 51% PDB header:protein transport Chain: A: PDB Molecule:pe family protein pe8; PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis Phyre2 PDB 1ygv chain A Region: 147 - 361 Aligned: 214 Modelled: 215 Confidence: 98.9% Identity: 28% PDB header:structural protein/contractile protein Chain: A: PDB Molecule:collagen i alpha 1; PDBTitle: the structure of collagen type i. single type i collagen2 molecule: rigid refinment Phyre2 PDB 3hqv chain B Region: 119 - 349 Aligned: 181 Modelled: 182 Confidence: 98.8% Identity: 31% PDB header:structural protein, contractile protein Chain: B: PDB Molecule:collagen alpha-2(i) chain; PDBTitle: low resolution, molecular envelope structure of type i2 collagen in situ determined by fiber diffraction. single3 type i collagen molecule, rigid body refinement Phyre2 PDB 1y0f chain B Region: 127 - 361 Aligned: 230 Modelled: 234 Confidence: 98.0% Identity: 32% PDB header:structural protein/contractile protein Chain: B: PDB Molecule:collagen i alpha 2; PDBTitle: the structure of collagen type i. single type i collagen2 molecule Phyre2 PDB 3boi chain B Region: 277 - 361 Aligned: 80 Modelled: 85 Confidence: 97.1% Identity: 31% PDB header:antifreeze protein Chain: B: PDB Molecule:6.5 kda glycine-rich antifreeze protein; PDBTitle: snow flea antifreeze protein racemate Phyre2 PDB 2pne chain A Region: 277 - 361 Aligned: 80 Modelled: 80 Confidence: 97.1% Identity: 31% PDB header:antifreeze protein Chain: A: PDB Molecule:6.5 kda glycine-rich antifreeze protein; PDBTitle: crystal structure of the snow flea antifreeze protein Phyre2 PDB 3boi chain A Region: 277 - 361 Aligned: 80 Modelled: 85 Confidence: 97.1% Identity: 31% PDB header:antifreeze protein Chain: A: PDB Molecule:6.5 kda glycine-rich antifreeze protein; PDBTitle: snow flea antifreeze protein racemate Phyre2 PDB 3bog chain A Region: 277 - 361 Aligned: 79 Modelled: 85 Confidence: 96.6% Identity: 32% PDB header:antifreeze protein Chain: A: PDB Molecule:6.5 kda glycine-rich antifreeze protein; PDBTitle: snow flea antifreeze protein quasi-racemate Phyre2 PDB 3bog chain B Region: 277 - 361 Aligned: 79 Modelled: 85 Confidence: 96.6% Identity: 32% PDB header:antifreeze protein Chain: B: PDB Molecule:6.5 kda glycine-rich antifreeze protein; PDBTitle: snow flea antifreeze protein quasi-racemate Phyre2 PDB 5ctd chain B Region: 156 - 196 Aligned: 41 Modelled: 41 Confidence: 94.2% Identity: 29% PDB header:structural protein Chain: B: PDB Molecule:collagen alpha-2(i) chain,collagen alpha-2(ix) chain; PDBTitle: crystal structure of the type ix collagen nc2 hetero-trimerization2 domain with a guest fragment a2a1a1 of type i collagen Phyre2 PDB 5ctd chain A Region: 156 - 194 Aligned: 39 Modelled: 39 Confidence: 94.1% Identity: 33% PDB header:structural protein Chain: A: PDB Molecule:collagen alpha-1(i) chain,collagen alpha-1(ix) chain; PDBTitle: crystal structure of the type ix collagen nc2 hetero-trimerization2 domain with a guest fragment a2a1a1 of type i collagen Phyre2 PDB 1nay chain C Region: 281 - 328 Aligned: 48 Modelled: 48 Confidence: 93.9% Identity: 23% PDB header:structural protein Chain: C: PDB Molecule:collagen-like peptide; PDBTitle: gpp-foldon:x-ray structure Phyre2 PDB 5cti chain C Region: 157 - 194 Aligned: 38 Modelled: 38 Confidence: 93.5% Identity: 29% PDB header:structural protein Chain: C: PDB Molecule:collagen alpha-1(i) chain,collagen alpha-3(ix) chain; PDBTitle: crystal structure of the type ix collagen nc2 hetero-trimerization2 domain with a guest fragment a2a1a1 of type i collagen (native form) Phyre2 PDB 2klw chain A Region: 162 - 191 Aligned: 30 Modelled: 30 Confidence: 66.8% Identity: 30% PDB header:de novo protein Chain: A: PDB Molecule:(pkg)10; PDBTitle: solution structure of an abc collagen heterotrimer reveals a2 single-register helix stabilized by electrostatic3 interactions Phyre2 PDB 1k6f chain B Region: 159 - 187 Aligned: 29 Modelled: 29 Confidence: 15.6% Identity: 28% PDB header:structural protein Chain: B: PDB Molecule:collagen triple helix; PDBTitle: crystal structure of the collagen triple helix model [(pro-pro-gly)2 10]3 Phyre2 PDB 1k6f chain D Region: 159 - 187 Aligned: 29 Modelled: 29 Confidence: 15.6% Identity: 28% PDB header:structural protein Chain: D: PDB Molecule:collagen triple helix; PDBTitle: crystal structure of the collagen triple helix model [(pro-pro-gly)2 10]3 Phyre2 PDB 1k6f chain C Region: 159 - 187 Aligned: 29 Modelled: 29 Confidence: 15.6% Identity: 28% PDB header:structural protein Chain: C: PDB Molecule:collagen triple helix; PDBTitle: crystal structure of the collagen triple helix model [(pro-pro-gly)2 10]3 Phyre2 PDB 1k6f chain F Region: 159 - 187 Aligned: 29 Modelled: 29 Confidence: 15.6% Identity: 28% PDB header:structural protein Chain: F: PDB Molecule:collagen triple helix; PDBTitle: crystal structure of the collagen triple helix model [(pro-pro-gly)2 10]3 Phyre2 1 d2g38a1 2 c2g38A_ 3 c5xfsA_ 4 c1ygvA_ 5 c3hqvB_ 6 c1y0fB_ 7 c3boiB_ 8 c2pneA_ 9 c3boiA_ 10 c3bogA_ 11 c3bogB_ 12 c5ctdB_ 13 c5ctdA_ 14 c1nayC_ 15 c5ctiC_ 16 c2klwA_ 17 c1k6fB_ 18 c1k6fD_ 19 c1k6fC_ 20 c1k6fF_ 21 22 23 24 25 26 27 28 29 30 31 32 33