1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	A	R	R	L	V	M	L	R	H	G	Q	T	D	Y	N	V	G	S	R	M	Q	G	Q	L	D	T	E	L	S	E	L	G	R	T	Q	A	V	A	A	A	E	V	L	G	K	R	Q	P	L	L	I	V	S	S	D	L	R	R
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	Y	D	T	A	V	K	L	G	E	R	T	G	L	V	V	R	V	D	T	R	L	R	E	T	H	L	G	D	W	Q	G	L	T	H	A	Q	I	D	A	D	A	P	G	A	R	L	A	W	R	E	D	A	T	W	A	P	H	G	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	S	R	V	D	V	A	A	R	S	R	P	L	V	A	E	L	V	A	S	E	P	E	W	G	G	A	D	E	P	D	R	P	V	V	L	V	A	H	G	G	L	I	A	A	L	S	A	A	L	L	K	L	P	V	A	N	W	P	A
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.
Sequence		L	G	G	M	G	N	A	S	W	T	Q	L	S	G	H	W	A	P	G	S	D	F	E	S	I	R	W	R	L	D	V	W	N	A	S	A	Q	V	S	S	D	V	L
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 43%) Beta strand ( 15%)

Rank Aligned region

PDB 4pz9 chain B Region: 3 - 216 Aligned: 208 Modelled: 214 Confidence: 100.0% Identity: 99% PDB header:hydrolase Chain: B: PDB Molecule:glucosyl-3-phosphoglycerate phosphatase; PDBTitle: the native structure of mycobacterial glucosyl-3-phosphoglycerate2 phosphatase rv2419c Phyre2 PDB 4ij5 chain B Region: 3 - 223 Aligned: 204 Modelled: 221 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: B: PDB Molecule:phosphoserine phosphatase 1; PDBTitle: crystal structure of a novel-type phosphoserine phosphatase from2 hydrogenobacter thermophilus tk-6 Phyre2 PDB 1h2e chain A Region: 3 - 220 Aligned: 202 Modelled: 218 Confidence: 100.0% Identity: 31% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 2yn0 chain A Region: 3 - 220 Aligned: 215 Modelled: 217 Confidence: 100.0% Identity: 18% PDB header:transcription Chain: A: PDB Molecule:transcription factor tau 55 kda subunit; PDBTitle: tau55 histidine phosphatase domain Phyre2 PDB 5zkk chain A Region: 3 - 218 Aligned: 196 Modelled: 216 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:phosphoglycerate mutase family protein, putative; PDBTitle: crystal structure of phosphoserine phosphatase from entamoeba2 histolytica Phyre2 PDB 4emb chain D Region: 5 - 218 Aligned: 201 Modelled: 214 Confidence: 100.0% Identity: 26% PDB header:isomerase Chain: D: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of a phosphoglycerate mutase gpma from borrelia2 burgdorferi b31 Phyre2 PDB 3r7a chain A Region: 1 - 218 Aligned: 200 Modelled: 214 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:phosphoglycerate mutase, putative; PDBTitle: crystal structure of phosphoglycerate mutase from bacillus anthracis2 str. sterne Phyre2 PDB 2yn2 chain A Region: 2 - 220 Aligned: 210 Modelled: 219 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ynl108c; PDBTitle: huf protein - paralogue of the tau55 histidine phosphatase domain Phyre2 PDB 3e9e chain B Region: 1 - 218 Aligned: 214 Modelled: 214 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: B: PDB Molecule:zgc:56074; PDBTitle: structure of full-length h11a mutant form of tigar from danio rerio Phyre2 PDB 1xq9 chain A Region: 1 - 213 Aligned: 198 Modelled: 213 Confidence: 100.0% Identity: 27% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 2a6p chain A Region: 2 - 217 Aligned: 191 Modelled: 213 Confidence: 100.0% Identity: 32% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible phosphoglycerate mutase gpm2; PDBTitle: structure solution to 2.2 angstrom and functional characterisation of2 the open reading frame rv3214 from mycobacterium tuberculosis Phyre2 PDB 1yjx chain D Region: 3 - 220 Aligned: 200 Modelled: 218 Confidence: 100.0% Identity: 24% PDB header:isomerase, hydrolase Chain: D: PDB Molecule:phosphoglycerate mutase 1; PDBTitle: crystal structure of human b type phosphoglycerate mutase Phyre2 PDB 1e58 chain A Region: 2 - 199 Aligned: 190 Modelled: 198 Confidence: 100.0% Identity: 24% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 6e4b chain C Region: 3 - 217 Aligned: 198 Modelled: 215 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: C: PDB Molecule:adenosylcobalamin/alpha-ribazole phosphatase; PDBTitle: the crystal structure of a putative alpha-ribazole-5'-p phosphatase2 from escherichia coli str. k-12 substr. mg1655 Phyre2 PDB 5vve chain A Region: 3 - 197 Aligned: 188 Modelled: 195 Confidence: 100.0% Identity: 26% PDB header:isomerase Chain: A: PDB Molecule:phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglycerate mutase from naegleria fowleri Phyre2 PDB 3ll4 chain B Region: 1 - 220 Aligned: 215 Modelled: 220 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein ykr043c; PDBTitle: structure of the h13a mutant of ykr043c in complex with fructose-1,6-2 bisphosphate Phyre2 PDB 3dcy chain A Region: 3 - 218 Aligned: 210 Modelled: 216 Confidence: 100.0% Identity: 28% PDB header:apoptosis regulator Chain: A: PDB Molecule:regulator protein; PDBTitle: crystal structure a tp53-induced glycolysis and apoptosis regulator2 protein from homo sapiens. Phyre2 PDB 1rii chain A Region: 2 - 197 Aligned: 189 Modelled: 196 Confidence: 100.0% Identity: 28% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 1qhf chain A Region: 5 - 197 Aligned: 186 Modelled: 193 Confidence: 100.0% Identity: 27% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 3f3k chain A Region: 1 - 220 Aligned: 215 Modelled: 220 Confidence: 100.0% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ykr043c; PDBTitle: the structure of uncharacterized protein ykr043c from saccharomyces2 cerevisiae. Phyre2 1 c4pz9B_ 2 c4ij5B_ 3 d1h2ea_ 4 c2yn0A_ 5 c5zkkA_ 6 c4embD_ 7 c3r7aA_ 8 c2yn2A_ 9 c3e9eB_ 10 d1xq9a_ 11 c2a6pA_ 12 c1yjxD_ 13 d1e58a_ 14 c6e4bC_ 15 c5vveA_ 16 c3ll4B_ 17 c3dcyA_ 18 d1riia_ 19 d1qhfa_ 20 c3f3kA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99