1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	V	R	A	E	H	C	R	G	A	G	G	C	D	E	C	P	S	V	M	P	E	H	P	T	A	L	F	H	D	V	A	A	I	A	L	A	Q	P	G	A	E	P	G	A	M	M	G	F	P	C	R	P	A	L	L	P	H	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?		?																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	R	A	V	M	R	C	V	R	T	R	S	A	S	T	S	L	G	V	S	V	I	A	G	Q	L	P	A	A	G	S	R	H	R	L	G	A	P	C	R	H	V	R	W	W	L	A	S	D	G	H	W	G	M	V	S	Y	I	P	T
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?							?	?			?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.
Sequence		A	L	N	V	S	M	G	G	I	V	G	W	R	C	V	P
Secondary structure
SS confidence
Disorder												?			?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 26%) Alpha helix ( 29%) Beta strand ( 26%)

Rank Aligned region

PDB 2ktc chain A Region: 10 - 18 Aligned: 9 Modelled: 9 Confidence: 21.8% Identity: 67% PDB header:toxin Chain: A: PDB Molecule:potassium channel toxin alpha-ktx 9.4; PDBTitle: solution structure of a novel hkv1.1 inhibiting scorpion toxin from2 mesibuthus tamulus Phyre2 PDB 1dnl chain A Region: 17 - 48 Aligned: 32 Modelled: 30 Confidence: 19.2% Identity: 25% Fold: Split barrel-like Superfamily: FMN-binding split barrel Family: PNP-oxidase like Phyre2 PDB 3h6q chain A Region: 98 - 136 Aligned: 39 Modelled: 39 Confidence: 16.8% Identity: 28% PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:macrocypin 1a; PDBTitle: macrocypin, a beta-trefoil cysteine protease inhibitor Phyre2 PDB 2rh2 chain A domain 1 Region: 127 - 134 Aligned: 8 Modelled: 8 Confidence: 16.0% Identity: 75% Fold: SH3-like barrel Superfamily: Electron transport accessory proteins Family: R67 dihydrofolate reductase Phyre2 PDB 2avu chain E domain 1 Region: 27 - 87 Aligned: 51 Modelled: 61 Confidence: 15.2% Identity: 24% Fold: FlhC-like Superfamily: FlhC-like Family: FlhC-like Phyre2 PDB 1wm8 chain A Region: 13 - 18 Aligned: 6 Modelled: 6 Confidence: 13.8% Identity: 83% PDB header:toxin Chain: A: PDB Molecule:neurotoxin bmp03; PDBTitle: solution structure of bmp03 from the venom of scorpion buthus2 martensii karsch, 10 structures Phyre2 PDB 2avu chain F Region: 27 - 87 Aligned: 51 Modelled: 61 Confidence: 13.3% Identity: 24% PDB header:transcription activator Chain: F: PDB Molecule:flagellar transcriptional activator flhc; PDBTitle: structure of the escherichia coli flhdc complex, a2 prokaryotic heteromeric regulator of transcription Phyre2 PDB 1du9 chain A Region: 13 - 18 Aligned: 6 Modelled: 6 Confidence: 13.1% Identity: 83% PDB header:toxin Chain: A: PDB Molecule:bmp02 neurotoxin; PDBTitle: solution structure of bmp02, a natural scorpion toxin which2 blocks apamin-sensitive calcium-activated potassium3 channels, 25 structures Phyre2 PDB 3bbn chain M Region: 90 - 100 Aligned: 11 Modelled: 11 Confidence: 10.3% Identity: 64% PDB header:ribosome Chain: M: PDB Molecule:ribosomal protein s13; PDBTitle: homology model for the spinach chloroplast 30s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome. Phyre2 PDB 1emo chain A domain 2 Region: 41 - 48 Aligned: 8 Modelled: 8 Confidence: 9.1% Identity: 75% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: EGF/Laminin Family: EGF-type module Phyre2 PDB 5ja9 chain D Region: 87 - 104 Aligned: 18 Modelled: 18 Confidence: 8.5% Identity: 22% PDB header:toxin Chain: D: PDB Molecule:toxin higb-2; PDBTitle: crystal structure of the higb2 toxin in complex with nb6 Phyre2 PDB 6gv7 chain A Region: 91 - 101 Aligned: 11 Modelled: 11 Confidence: 8.5% Identity: 45% PDB header:metal binding protein Chain: A: PDB Molecule:metallothionein; PDBTitle: cadmium(ii) form of a44h mutant of shortened metallothionein from2 pseudomonas fluorescens q2-87 (residues 1-52) Phyre2 PDB 5buz chain C Region: 28 - 41 Aligned: 14 Modelled: 14 Confidence: 7.1% Identity: 36% PDB header:transport protein Chain: C: PDB Molecule:snap receptor-like protein; PDBTitle: crystal structure of a complex between the snare vam3 and the hops2 vps33-vps16 subcomplex from chaetomium thermophilum Phyre2 PDB 3ebx chain A Region: 13 - 22 Aligned: 9 Modelled: 10 Confidence: 6.5% Identity: 67% Fold: Snake toxin-like Superfamily: Snake toxin-like Family: Snake venom toxins Phyre2 PDB 5mxn chain A Region: 26 - 49 Aligned: 24 Modelled: 24 Confidence: 6.3% Identity: 38% PDB header:transport protein Chain: A: PDB Molecule:type vi secretion protein; PDBTitle: atomic model of the vipa/vipb/hcp, the type six secretion system non-2 contractile sheath-tube of vibrio cholerae from cryo-em Phyre2 PDB 1qm4 chain A domain 2 Region: 14 - 22 Aligned: 9 Modelled: 9 Confidence: 5.9% Identity: 44% Fold: S-adenosylmethionine synthetase Superfamily: S-adenosylmethionine synthetase Family: S-adenosylmethionine synthetase Phyre2 PDB 5o5j chain M Region: 90 - 103 Aligned: 14 Modelled: 14 Confidence: 5.7% Identity: 57% PDB header:ribosome Chain: M: PDB Molecule:30s ribosomal protein s13; PDBTitle: structure of the 30s small ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 1im3 chain D Region: 114 - 136 Aligned: 23 Modelled: 23 Confidence: 5.7% Identity: 43% Fold: Immunoglobulin-like beta-sandwich Superfamily: E set domains Family: Cytomegalovirus protein US2 Phyre2 PDB 2gy9 chain M domain 1 Region: 90 - 103 Aligned: 14 Modelled: 14 Confidence: 5.7% Identity: 57% Fold: S13-like H2TH domain Superfamily: S13-like H2TH domain Family: Ribosomal protein S13 Phyre2 PDB 2p02 chain A domain 2 Region: 14 - 22 Aligned: 9 Modelled: 9 Confidence: 5.7% Identity: 44% Fold: S-adenosylmethionine synthetase Superfamily: S-adenosylmethionine synthetase Family: S-adenosylmethionine synthetase Phyre2 1 c2ktcA_ 2 d1dnla_ 3 c3h6qA_ 4 d2rh2a1 5 d2avue1 6 c1wm8A_ 7 c2avuF_ 8 c1du9A_ 9 c3bbnM_ 10 d1emoa2 11 c5ja9D_ 12 c6gv7A_ 13 c5buzC_ 14 d3ebxa_ 15 c5mxnA_ 16 d1qm4a2 17 c5o5jM_ 18 d1im3d_ 19 d2gy9m1 20 d2p02a2 21 22 23 24 25 26 27 28 29 30 31