1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	G	L	R	D	A	D	E	R	W	D	T	V	G	Q	A	I	G	L	F	L	R	G	H	T	L	R	T	A	A	P	T	A	L	I	V	G	T	V	L	C	A	V	N	Q	G	A	T	L	A	E	G	A	A	T	I	G	T	W	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.
Sequence		R	M	V	I	N	Y	L	V	P	F	L	V	A	S	V	G	Y	L	G	A	R	R	G	V	R	R	A	S	G	R	S	D	P	S	A	Q
Secondary structure
SS confidence
Disorder																													?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 83%) Beta strand ( 0%) TM helix ( 36%) (View membrane topology prediction)

Rank Aligned region

PDB 1o82 chain A Region: 33 - 49 Aligned: 17 Modelled: 17 Confidence: 27.9% Identity: 41% Fold: Saposin-like Superfamily: Bacteriocin AS-48 Family: Bacteriocin AS-48 Phyre2 PDB 5kw2 chain A Region: 58 - 89 Aligned: 32 Modelled: 32 Confidence: 21.2% Identity: 16% PDB header:fatty acid binding protein/hydrolase Chain: A: PDB Molecule:free fatty acid receptor 1,lysozyme,free fatty acid PDBTitle: the extra-helical binding site of gpr40 and the structural basis for2 allosteric agonism and incretin stimulation Phyre2 PDB 2kk1 chain A Region: 61 - 71 Aligned: 11 Modelled: 11 Confidence: 20.7% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase abl2; PDBTitle: solution structure of c-terminal domain of tyrosine-protein2 kinase abl2 from homo sapiens, northeast structural3 genomics consortium (nesg) target hr5537a Phyre2 PDB 1iij chain A Region: 32 - 43 Aligned: 12 Modelled: 12 Confidence: 16.3% Identity: 33% PDB header:signaling protein Chain: A: PDB Molecule:erbb-2 receptor protein-tyrosine kinase; PDBTitle: solution structure of the neu/erbb-2 membrane spanning2 segment Phyre2 PDB 1jmx chain A domain 2 Region: 39 - 75 Aligned: 37 Modelled: 37 Confidence: 16.3% Identity: 22% Fold: Cytochrome c Superfamily: Cytochrome c Family: Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2 Phyre2 PDB 1pby chain A domain 2 Region: 39 - 75 Aligned: 37 Modelled: 37 Confidence: 15.0% Identity: 24% Fold: Cytochrome c Superfamily: Cytochrome c Family: Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2 Phyre2 PDB 2mmj chain A Region: 30 - 39 Aligned: 10 Modelled: 10 Confidence: 11.9% Identity: 40% PDB header:antimicrobial protein Chain: A: PDB Molecule:maculatin g15; PDBTitle: structure of a peptoid analogue of maculatin g15 in dpc micelles Phyre2 PDB 4wrp chain B Region: 3 - 32 Aligned: 30 Modelled: 30 Confidence: 11.8% Identity: 17% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: the c-terminal domain of gene product lpg0944 from legionella2 pneumophila subsp. pneumophila str. philadelphia 1 Phyre2 PDB 1jmx chain A Region: 39 - 71 Aligned: 33 Modelled: 33 Confidence: 10.4% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:amine dehydrogenase; PDBTitle: crystal structure of a quinohemoprotein amine dehydrogenase2 from pseudomonas putida Phyre2 PDB 5lc5 chain C Region: 56 - 66 Aligned: 11 Modelled: 11 Confidence: 9.1% Identity: 9% PDB header:oxidoreductase Chain: C: PDB Molecule:nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, PDBTitle: structure of mammalian respiratory complex i, class2 Phyre2 PDB 2ld7 chain B Region: 42 - 67 Aligned: 26 Modelled: 26 Confidence: 8.3% Identity: 12% PDB header:transcription Chain: B: PDB Molecule:paired amphipathic helix protein sin3a; PDBTitle: solution structure of the msin3a pah3-sap30 sid complex Phyre2 PDB 2l53 chain B Region: 17 - 33 Aligned: 17 Modelled: 17 Confidence: 7.9% Identity: 29% PDB header:ca-binding protein/proton transport Chain: B: PDB Molecule:voltage-gated sodium channel type v alpha isoform b PDBTitle: solution nmr structure of apo-calmodulin in complex with the iq motif2 of human cardiac sodium channel nav1.5 Phyre2 PDB 2kpe chain B Region: 33 - 42 Aligned: 10 Modelled: 10 Confidence: 7.2% Identity: 40% PDB header:membrane protein Chain: B: PDB Molecule:glycophorin-a; PDBTitle: refined structure of glycophorin a transmembrane segment dimer in dpc2 micelles Phyre2 PDB 2kpe chain A Region: 33 - 42 Aligned: 10 Modelled: 10 Confidence: 7.2% Identity: 40% PDB header:membrane protein Chain: A: PDB Molecule:glycophorin-a; PDBTitle: refined structure of glycophorin a transmembrane segment dimer in dpc2 micelles Phyre2 PDB 2amn chain A Region: 13 - 31 Aligned: 19 Modelled: 19 Confidence: 7.1% Identity: 21% PDB header:antimicrobial protein Chain: A: PDB Molecule:cathelicidin; PDBTitle: solution structure of fowlicidin-1, a novel cathelicidin2 antimicrobial peptide from chicken Phyre2 PDB 5eh6 chain A Region: 32 - 42 Aligned: 11 Modelled: 11 Confidence: 6.9% Identity: 36% PDB header:membrane protein Chain: A: PDB Molecule:glycophorin-a; PDBTitle: crystal structure of the glycophorin a transmembrane monomer in2 lipidic cubic phase Phyre2 PDB 5eh4 chain A Region: 32 - 42 Aligned: 11 Modelled: 11 Confidence: 6.9% Identity: 36% PDB header:membrane protein Chain: A: PDB Molecule:glycophorin-a; PDBTitle: crystal structure of the glycophorin a transmembrane dimer in lipidic2 cubic phase Phyre2 PDB 5eh4 chain B Region: 32 - 42 Aligned: 11 Modelled: 11 Confidence: 6.9% Identity: 36% PDB header:membrane protein Chain: B: PDB Molecule:glycophorin-a; PDBTitle: crystal structure of the glycophorin a transmembrane dimer in lipidic2 cubic phase Phyre2 PDB 5eh4 chain D Region: 32 - 42 Aligned: 11 Modelled: 11 Confidence: 6.9% Identity: 36% PDB header:membrane protein Chain: D: PDB Molecule:glycophorin-a; PDBTitle: crystal structure of the glycophorin a transmembrane dimer in lipidic2 cubic phase Phyre2 PDB 5eh4 chain C Region: 32 - 42 Aligned: 11 Modelled: 11 Confidence: 6.9% Identity: 36% PDB header:membrane protein Chain: C: PDB Molecule:glycophorin-a; PDBTitle: crystal structure of the glycophorin a transmembrane dimer in lipidic2 cubic phase Phyre2 1 d1o82a_ 2 c5kw2A_ 3 c2kk1A_ 4 c1iijA_ 5 d1jmxa2 6 d1pbya2 7 c2mmjA_ 8 c4wrpB_ 9 c1jmxA_ 10 c5lc5c_ 11 c2ld7B_ 12 c2l53B_ 13 c2kpeB_ 14 c2kpeA_ 15 c2amnA_ 16 c5eh6A_ 17 c5eh4A_ 18 c5eh4B_ 19 c5eh4D_ 20 c5eh4C_ 21 22 23 24 25