Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD2435c_(-)_2730567_2732759
DateWed Aug 7 12:50:05 BST 2019
Unique Job ID1621a807d566e316
SequenceLTSGEALDSV ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:76.309 Y:51.880 Z:60.542
Model (left) based on template c6r4oA_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a truncated adenylyl cyclase bound to mant-gtp, forskolin2 and an activated stimulatory galphas protein
Confidence and coverage
Confidence:100.0% Coverage: 30%
220 residues ( 30% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
589 residues ( 81%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6r4oA_
100.0 22
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a truncated adenylyl cyclase bound to mant-gtp, forskolin2 and an activated stimulatory galphas protein
2c6fhtB_
100.0 24
PDB header:lyase
Chain: B: PDB Molecule:bacteriophytochrome,adenylate cyclase;
PDBTitle: crystal structure of an artificial phytochrome regulated2 adenylate/guanylate cyclase in its dark adapted pr form
3c6r4pA_
100.0 25
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a soluble domain of adenylyl cyclase bound to an2 activated stimulatory g protein
4c4yusA_
99.9 18
PDB header:lyase
Chain: A: PDB Molecule:family 3 adenylate cyclase;
PDBTitle: crystal structure of photoactivated adenylyl cyclase of a2 cyanobacteriaoscillatoria acuminata in hexagonal form
5c5nbyA_
99.9 21
PDB header:lyase
Chain: A: PDB Molecule:beta subunit of photoactivated adenylyl cyclase;
PDBTitle: structure of a bacterial light-regulated adenylyl cylcase
6c5o5kC_
99.9 31
PDB header:membrane protein
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: x-ray structure of a bacterial adenylyl cyclase soluble domain
7c1cjkA_
99.9 28
PDB header:lyase/lyase/signaling protein
Chain: A: PDB Molecule:adenylate cyclase, type v;
PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn
8d1azsa_
99.9 28
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
9c4cllA_
99.9 17
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase type 10;
PDBTitle: crystal structure of human soluble adenylyl cyclase in complex with2 bicarbonate
10c1wc6B_
99.9 19
PDB header:lyase
Chain: B: PDB Molecule:adenylate cyclase;
PDBTitle: soluble adenylyl cyclase cyac from s. platensis in complex2 with rp-atpalphas in presence of bicarbonate
11c2w01C_
99.9 27
PDB header:lyase
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of the guanylyl cyclase cya2
12d1wc1a_
99.8 20
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
13c3r5gB_
99.8 25
PDB header:lyase
Chain: B: PDB Molecule:cyab;
PDBTitle: crystal structure of the adenylyl cyclase cyab from p. aeruginosa
14c3uvjC_
99.8 26
PDB header:lyase
Chain: C: PDB Molecule:guanylate cyclase soluble subunit alpha-3;
PDBTitle: crystal structure of the catalytic domain of the heterodimeric human2 soluble guanylate cyclase 1.
15d1azsb_
99.8 31
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
16c1y10C_
99.8 21
PDB header:lyase
Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302;
PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state
17d1fx2a_
99.8 19
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
18c2wz1B_
99.8 23
PDB header:lyase
Chain: B: PDB Molecule:guanylate cyclase soluble subunit beta-1;
PDBTitle: structure of the catalytic domain of human soluble guanylate cyclase 12 beta 3.
19c6fu4D_
99.8 15
PDB header:signaling protein
Chain: D: PDB Molecule:probable chemotaxis transducer;
PDBTitle: ligand binding domain (lbd) of the p. aeruginosa histamine receptor2 tlpq
20c5t65A_
99.8 16
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein pcta;
PDBTitle: ligand binding domain of pseudomonas aeruginosa pao1 amino acid2 chemoreceptor pcta in complex with l-ile
21d1fx4a_
not modelled 99.8 23
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
22c4wy9A_
not modelled 99.8 14
PDB header:signaling protein
Chain: A: PDB Molecule:putative mcp-type signal transduction protein;
PDBTitle: crystal structure of the periplasmic sensory domain of the2 campylobacter jejuni chemoreceptor tlp1
23c6dtmA_
not modelled 99.8 16
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein tlpa;
PDBTitle: crystal structure of helicobacter pylori tlpa chemoreceptor ligand2 binding domain
24c1yk9A_
not modelled 99.8 34
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of a mutant form of the mycobacterial2 adenylyl cyclase rv1625c
25c4xmrB_
not modelled 99.8 17
PDB header:signaling protein
Chain: B: PDB Molecule:putative methyl-accepting chemotaxis signal transduction
PDBTitle: crystal structure of the sensory domain of the campylobacter jejuni2 chemoreceptor tlp3 (ccml) with isoleucine bound.
26c6aoaA_
not modelled 99.8 26
PDB header:lyase
Chain: A: PDB Molecule:bacterio-rhodopsin/guanylyl cyclase 1 fusion protein;
PDBTitle: monomeric crystal structure of the e497/c566d double mutant of the2 guanylyl cyclase domain of the rhogc fusion protein from the aquatic3 fungus blastocladiella emersonii
27c6d8vA_
not modelled 99.8 12
PDB header:membrane protein
Chain: A: PDB Molecule:probable chemoreceptor (methyl-accepting chemotaxis)
PDBTitle: methyl-accepting chemotaxis protein x
28c3c8cB_
not modelled 99.8 12
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of mcp_n and cache domains of methyl-accepting2 chemotaxis protein from vibrio cholerae
29c2p7jA_
not modelled 99.8 10
PDB header:transcription
Chain: A: PDB Molecule:putative sensory box/ggdef family protein;
PDBTitle: crystal structure of the domain of putative sensory box/ggdef family2 protein from vibrio parahaemolyticus
30c3libA_
not modelled 99.8 15
PDB header:signaling protein
Chain: A: PDB Molecule:hypothetical sensory transduction histidine kinase;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase mmhk1s-z3
31c5ltoB_
not modelled 99.8 23
PDB header:signaling protein
Chain: B: PDB Molecule:methyl-accepting chemotaxis protein pctb;
PDBTitle: ligand binding domain of pseudomonas aeruginosa pao1 amino acid2 chemorecpetors pctb in complex with l-gln
32c6ioqA_
not modelled 99.8 15
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: the ligand binding domain of mlp24 with glycine
33c6f9gE_
not modelled 99.8 13
PDB header:signaling protein
Chain: E: PDB Molecule:methyl-accepting chemotaxis protein mcpu;
PDBTitle: ligand binding domain of p. putida kt2440 polyamine chemorecpetors2 mcpu in complex putrescine.
34c5wbfB_
not modelled 99.7 14
PDB header:signaling protein
Chain: B: PDB Molecule:methyl-accepting chemotaxis transducer (tlpc);
PDBTitle: double cache (dcache) sensing domain of tlpc chemoreceptor from2 helicobacter pylori
35c3liaA_
not modelled 99.7 16
PDB header:signaling protein
Chain: A: PDB Molecule:hypothetical sensory transduction histidine kinase;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase mmhk1s-z2
36c3e4pB_
not modelled 99.7 15
PDB header:transferase
Chain: B: PDB Molecule:c4-dicarboxylate transport sensor protein dctb;
PDBTitle: crystal structure of malonate occupied dctb
37c1ybuA_
not modelled 99.7 19
PDB header:hydrolase
Chain: A: PDB Molecule:lipj;
PDBTitle: mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex2 with a substrate analog.
38c5ltvA_
not modelled 99.7 16
PDB header:signaling protein
Chain: A: PDB Molecule:chemotactic transducer pctc;
PDBTitle: ligand binding regions of pseudomonas aeruginosa pao1 amino acid2 chemoreceptors pctc in complex with gaba
39c4wp3E_
not modelled 99.7 15
PDB header:lyase
Chain: E: PDB Molecule:ma1120;
PDBTitle: crystal structure of adenylyl cyclase from mycobacterium avium ma11202 wild type
40c3et6A_
not modelled 99.7 31
PDB header:lyase
Chain: A: PDB Molecule:soluble guanylyl cyclase beta;
PDBTitle: the crystal structure of the catalytic domain of a eukaryotic2 guanylate cyclase
41c3mr7B_
not modelled 99.7 25
PDB header:hydrolase
Chain: B: PDB Molecule:adenylate/guanylate cyclase/hydrolase, alpha/beta fold
PDBTitle: crystal structure of adenylate/guanylate cyclase/hydrolase from2 silicibacter pomeroyi
42c3lifA_
not modelled 99.7 16
PDB header:signaling protein
Chain: A: PDB Molecule:putative diguanylate cyclase (ggdef) with pas/pac domain;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase rphk1s-z16
43c3by9A_
not modelled 99.7 13
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of the v. cholerae histidine kinase dctb sensor2 domain
44c3licA_
not modelled 99.7 20
PDB header:signaling protein
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase sohk1s-z6
45c4e40A_
not modelled 99.5 7
PDB header:transport protein
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: the haptoglobin-hemoglobin receptor of trypanosoma congolense
46c3fosA_
not modelled 99.4 14
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of two-component sensor histidine kinase domain from2 bacillus subtilis subsp. subtilis str. 168
47d2p7ja2
not modelled 99.4 11
Fold:Profilin-like
Superfamily:Sensory domain-like
Family:YkuI C-terminal domain-like
48c3ur1C_
not modelled 99.3 12
PDB header:immune system
Chain: C: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: the structure of a ternary complex between chea domains p4 and p5 with2 chew and with a truncated fragment of tm14, a chemoreceptor analog3 from thermotoga maritima.
49c3zx6A_
not modelled 99.1 15
PDB header:signaling
Chain: A: PDB Molecule:hamp, methyl-accepting chemotaxis protein i;
PDBTitle: structure of hamp(af1503)-tsr fusion - hamp (a291v) mutant
50c4ywzA_
not modelled 98.8 15
PDB header:transferase
Chain: A: PDB Molecule:sensor protein kinase walk;
PDBTitle: crystal structure of the extracellular receptor domain of the2 essential sensor kinase walk from staphylococcus aureus
51c5ereA_
not modelled 98.8 17
PDB header:signaling protein
Chain: A: PDB Molecule:extracellular ligand-binding receptor;
PDBTitle: extracellular ligand binding receptor from desulfohalobium retbaense2 dsm5692
52c1qu7A_
not modelled 98.7 16
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein i;
PDBTitle: four helical-bundle structure of the cytoplasmic domain of a serine2 chemotaxis receptor
53c5jefA_
not modelled 98.3 23
PDB header:transferase
Chain: A: PDB Molecule:nitrate/nitrite sensor protein narq;
PDBTitle: fragment of nitrate/nitrite sensor histidine kinase narq (wt) in2 asymmetric holo state
54c4gn0D_
not modelled 98.3 24
PDB header:signaling protein
Chain: D: PDB Molecule:hamp domain of af1503;
PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method
55c5gjvF_
not modelled 98.3 16
PDB header:membrane protein
Chain: F: PDB Molecule:voltage-dependent calcium channel subunit alpha-2/delta-1;
PDBTitle: structure of the mammalian voltage-gated calcium channel cav1.12 complex at near atomic resolution
56c3lnrA_
not modelled 97.8 12
PDB header:signaling protein
Chain: A: PDB Molecule:aerotaxis transducer aer2;
PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2
57d1p0za_
not modelled 97.8 18
Fold:Profilin-like
Superfamily:Sensory domain-like
Family:Sensory domain of two-component sensor kinase
58d3by8a1
not modelled 97.7 11
Fold:Profilin-like
Superfamily:Sensory domain-like
Family:Sensory domain of two-component sensor kinase
59c2ch7A_
not modelled 97.6 8
PDB header:chemotaxis
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of the cytoplasmic domain of a bacterial2 chemoreceptor from thermotoga maritima
60d2basa2
not modelled 97.3 12
Fold:Profilin-like
Superfamily:Sensory domain-like
Family:YkuI C-terminal domain-like
61c3jbrF_
not modelled 97.2 17
PDB header:membrane protein
Chain: F: PDB Molecule:voltage-dependent calcium channel subunit alpha-2/delta-1;
PDBTitle: cryo-em structure of the rabbit voltage-gated calcium channel cav1.12 complex at 4.2 angstrom
62d2asxa1
not modelled 97.0 31
Fold:HAMP domain-like
Superfamily:HAMP domain-like
Family:HAMP domain
63c3g67A_
not modelled 96.8 9
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of a soluble chemoreceptor from thermotoga2 maritima
64c2qhkA_
not modelled 96.7 9
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of methyl-accepting chemotaxis protein from vibrio2 parahaemolyticus rimd 2210633
65c4exoA_
not modelled 96.6 9
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: revised, rerefined crystal structure of pdb entry 2qhk, methyl2 accepting chemotaxis protein
66c3ub9B_
not modelled 96.6 12
PDB header:membrane protein
Chain: B: PDB Molecule:chemoreceptor tlpb;
PDBTitle: periplasmic portion of the helicobacter pylori chemoreceptor tlpb with2 hydroxyurea bound
67c5g4yA_
not modelled 96.0 11
PDB header:signaling protein
Chain: A: PDB Molecule:chemotaxis protein;
PDBTitle: structural basis for carboxylic acid recognition by a cache2 chemosensory domain.
68c4onxB_
not modelled 95.9 20
PDB header:transferase
Chain: B: PDB Molecule:sensor histidine kinase;
PDBTitle: 2.8 angstrom crystal structure of sensor domain of histidine kinase2 from clostridium perfringens.
69c4k08A_
not modelled 95.6 11
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis sensory transducer;
PDBTitle: periplasmic sensor domain of chemotaxis protein, adeh_3718
70c3zrwB_
not modelled 94.8 23
PDB header:signaling protein
Chain: B: PDB Molecule:af1503 protein, osmolarity sensor protein envz;
PDBTitle: the structure of the dimeric hamp-dhp fusion a291v mutant
71c2w27A_
not modelled 94.8 12
PDB header:signaling protein
Chain: A: PDB Molecule:ykui protein;
PDBTitle: crystal structure of the bacillus subtilis ykui protein, with an eal2 domain, in complex with substrate c-di-gmp and calcium
72c4i5sA_
not modelled 93.3 16
PDB header:transferase
Chain: A: PDB Molecule:putative histidine kinase covs; vick-like protein;
PDBTitle: structure and function of sensor histidine kinase
73c2rm8A_
not modelled 93.1 38
PDB header:signaling protein
Chain: A: PDB Molecule:sensory rhodopsin ii transducer;
PDBTitle: the solution structure of phototactic transducer protein2 htrii linker region from natronomonas pharaonis
74c4ctiA_
not modelled 86.7 30
PDB header:signaling protein
Chain: A: PDB Molecule:osmolarity sensor protein envz, af1503;
PDBTitle: escherichia coli envz histidine kinase catalytic part fused to2 archaeoglobus fulgidus af1503 hamp domain
75c2qkpD_
not modelled 86.5 15
PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of c-terminal domain of smu_1151c from streptococcus2 mutans
76c4biuB_
not modelled 84.1 21
PDB header:transferase
Chain: B: PDB Molecule:sensor protein cpxa;
PDBTitle: crystal structure of cpxahdc (orthorhombic form 1)
77c3caxA_
not modelled 80.3 8
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein pf0695;
PDBTitle: crystal structure of uncharacterized protein pf0695
78c5fq1A_
not modelled 68.0 15
PDB header:transferase
Chain: A: PDB Molecule:histidine kinase;
PDBTitle: structure of the cytoplasmic pas domain of the geobacillus2 thermodenitrificans histidine kinase cita
79c3b42B_
not modelled 64.4 21
PDB header:signaling protein
Chain: B: PDB Molecule:methyl-accepting chemotaxis protein, putative;
PDBTitle: periplasmic sensor domain of chemotaxis protein gsu0935
80c3mxqC_
not modelled 62.1 18
PDB header:transferase
Chain: C: PDB Molecule:sensor protein;
PDBTitle: crystal structure of sensory box sensor histidine kinase from vibrio2 cholerae
81d2hjea1
not modelled 61.0 14
Fold:Profilin-like
Superfamily:Sensory domain-like
Family:LuxQ-periplasmic domain-like
82c5iu1A_
not modelled 54.4 21
PDB header:plant protein
Chain: A: PDB Molecule:ctr1-like protein;
PDBTitle: n-terminal pas domain homodimer of ppanr map3k from physcomitrella2 patens.
83c3c38A_
not modelled 52.0 12
PDB header:signaling protein, transferase
Chain: A: PDB Molecule:autoinducer 2 sensor kinase/phosphatase luxq;
PDBTitle: crystal structure of the periplasmic domain of vibrio2 cholerae luxq
84c2kseA_
not modelled 51.6 18
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c
85c2gx5B_
not modelled 44.7 10
PDB header:transcription
Chain: B: PDB Molecule:gtp-sensing transcriptional pleiotropic repressor cody;
PDBTitle: n-terminal gaf domain of transcriptional pleiotropic repressor cody
86c2w0nA_
not modelled 43.9 19
PDB header:transferase
Chain: A: PDB Molecule:sensor protein dcus;
PDBTitle: plasticity of pas domain and potential role for signal2 transduction in the histidine-kinase dcus
87c5ey0A_
not modelled 43.4 18
PDB header:transcription
Chain: A: PDB Molecule:gtp-sensing transcriptional pleiotropic repressor cody;
PDBTitle: crystal structure of cody from staphylococcus aureus with gtp and ile
88c4fofA_
not modelled 38.4 13
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of the blue-light absorbing form of the2 thermosynechococcus elongatus pixj gaf-domain
89c2gj3A_
not modelled 37.8 16
PDB header:transferase
Chain: A: PDB Molecule:nitrogen fixation regulatory protein;
PDBTitle: crystal structure of the fad-containing pas domain of the protein nifl2 from azotobacter vinelandii.
90c2kogA_
not modelled 36.8 9
PDB header:membrane protein
Chain: A: PDB Molecule:vesicle-associated membrane protein 2;
PDBTitle: lipid-bound synaptobrevin solution nmr structure
91c2ykfA_
not modelled 31.8 15
PDB header:transferase
Chain: A: PDB Molecule:probable sensor histidine kinase pdtas;
PDBTitle: sensor region of a sensor histidine kinase
92c5ey2A_
not modelled 29.6 15
PDB header:transcription
Chain: A: PDB Molecule:gtp-sensing transcriptional pleiotropic repressor cody;
PDBTitle: crystal structure of cody from bacillus cereus
93c5wdaL_
not modelled 29.0 15
PDB header:protein transport
Chain: L: PDB Molecule:general secretion pathway protein g;
PDBTitle: structure of the pulg pseudopilus
94c3bjnA_
not modelled 26.9 24
PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, putative;
PDBTitle: crystal structure of c-terminal domain of putative transcriptional2 regulator from vibrio cholerae, targeted domain 79-240
95c2qv6D_
not modelled 23.5 14
PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase iii;
PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions
96c3lyxA_
not modelled 22.6 13
PDB header:transcription
Chain: A: PDB Molecule:sensory box/ggdef domain protein;
PDBTitle: crystal structure of the pas domain of the protein cps_12912 from colwellia psychrerythraea. northeast structural3 genomics consortium target id csr222b
97d1oqwa_
not modelled 19.9 15
Fold:Pili subunits
Superfamily:Pili subunits
Family:Pilin
98c3mmhA_
not modelled 19.4 14
PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine-r-sulfoxide reductase;
PDBTitle: x-ray structure of free methionine-r-sulfoxide reductase from2 neisseria meningitidis in complex with its substrate
99c2w1rA_
not modelled 17.9 9
PDB header:transcription
Chain: A: PDB Molecule:stage v sporulation protein t;
PDBTitle: crystal structure of the c-terminal domain of b. subtilis spovt

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Transmembrane helix prediction 

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