1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	H	K	K	G	A	S	S	S	R	N	G	R	D	S	A	A	Q	R	L	G	V	K	R	Y	G	G	Q	V	V	K	A	G	E	I	L	V	R	Q	R	G	T	K	F	H	P	G	V	N	V	G	R	G	G	D	D	T	L	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.
Sequence		A	K	T	A	G	A	V	E	F	G	I	K	R	G	R	K	T	V	S	I	V	G	S	T	T	A
Secondary structure
SS confidence
Disorder																							?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 0%) Beta strand ( 52%)

Rank Aligned region

PDB 3fin chain 0 Region: 1 - 84 Aligned: 84 Modelled: 84 Confidence: 100.0% Identity: 63% PDB header:ribosome Chain: 0: PDB Molecule:50s ribosomal protein l27; PDBTitle: t. thermophilus 70s ribosome in complex with mrna, trnas and ef-2 tu.gdp.kirromycin ternary complex, fitted to a 6.4 a cryo-em map.3 this file contains the 50s subunit. Phyre2 PDB 2zjr chain T domain 1 Region: 2 - 84 Aligned: 83 Modelled: 83 Confidence: 100.0% Identity: 59% Fold: Barrel-sandwich hybrid Superfamily: Ribosomal L27 protein-like Family: Ribosomal L27 protein Phyre2 PDB 3bbo chain X Region: 2 - 86 Aligned: 85 Modelled: 85 Confidence: 100.0% Identity: 56% PDB header:ribosome Chain: X: PDB Molecule:ribosomal protein l27; PDBTitle: homology model for the spinach chloroplast 50s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome Phyre2 PDB 5mlc chain X Region: 3 - 85 Aligned: 83 Modelled: 83 Confidence: 100.0% Identity: 58% PDB header:ribosome Chain: X: PDB Molecule:50s ribosomal protein l27, chloroplastic; PDBTitle: cryo-em structure of the spinach chloroplast ribosome reveals the2 location of plastid-specific ribosomal proteins and extensions Phyre2 PDB 2gyc chain U domain 1 Region: 2 - 83 Aligned: 82 Modelled: 82 Confidence: 100.0% Identity: 63% Fold: Barrel-sandwich hybrid Superfamily: Ribosomal L27 protein-like Family: Ribosomal L27 protein Phyre2 PDB 5o60 chain X Region: 8 - 85 Aligned: 78 Modelled: 78 Confidence: 100.0% Identity: 86% PDB header:ribosome Chain: X: PDB Molecule:50s ribosomal protein l27; PDBTitle: structure of the 50s large ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 1vw4 chain R Region: 9 - 81 Aligned: 73 Modelled: 73 Confidence: 100.0% Identity: 48% PDB header:ribosome Chain: R: PDB Molecule:54s ribosomal protein l2, mitochondrial; PDBTitle: structure of the yeast mitochondrial large ribosomal subunit Phyre2 PDB 4wf9 chain T Region: 11 - 84 Aligned: 74 Modelled: 74 Confidence: 100.0% Identity: 61% PDB header:ribosome Chain: T: PDB Molecule:50s ribosomal protein l27; PDBTitle: the crystal structure of the large ribosomal subunit of staphylococcus2 aureus in complex with telithromycin Phyre2 PDB 4v19 chain 0 Region: 6 - 85 Aligned: 80 Modelled: 80 Confidence: 100.0% Identity: 36% PDB header:ribosome Chain: 0: PDB Molecule:mitoribosomal protein bl27m, mrpl27; PDBTitle: structure of the large subunit of the mammalian mitoribosome, part 12 of 2 Phyre2 PDB 2ftc chain O Region: 2 - 69 Aligned: 68 Modelled: 68 Confidence: 100.0% Identity: 41% PDB header:ribosome Chain: O: PDB Molecule:mitochondrial 39s ribosomal protein l27; PDBTitle: structural model for the large subunit of the mammalian mitochondrial2 ribosome Phyre2 PDB 1v8q chain A Region: 20 - 84 Aligned: 65 Modelled: 65 Confidence: 100.0% Identity: 60% Fold: Barrel-sandwich hybrid Superfamily: Ribosomal L27 protein-like Family: Ribosomal L27 protein Phyre2 PDB 2ba0 chain A domain 2 Region: 29 - 84 Aligned: 48 Modelled: 56 Confidence: 95.5% Identity: 17% Fold: Barrel-sandwich hybrid Superfamily: Ribosomal L27 protein-like Family: ECR1 N-terminal domain-like Phyre2 PDB 2je6 chain I domain 2 Region: 29 - 84 Aligned: 49 Modelled: 56 Confidence: 95.3% Identity: 14% Fold: Barrel-sandwich hybrid Superfamily: Ribosomal L27 protein-like Family: ECR1 N-terminal domain-like Phyre2 PDB 2nn6 chain H domain 2 Region: 29 - 82 Aligned: 47 Modelled: 54 Confidence: 94.4% Identity: 28% Fold: Barrel-sandwich hybrid Superfamily: Ribosomal L27 protein-like Family: ECR1 N-terminal domain-like Phyre2 PDB 4ifd chain I Region: 29 - 86 Aligned: 57 Modelled: 58 Confidence: 93.9% Identity: 25% PDB header:hydrolase/rna Chain: I: PDB Molecule:exosome complex component csl4; PDBTitle: crystal structure of an 11-subunit eukaryotic exosome complex bound to2 rna Phyre2 PDB 6d6r chain H Region: 29 - 82 Aligned: 47 Modelled: 54 Confidence: 93.0% Identity: 28% PDB header:hydrolase Chain: H: PDB Molecule:exosome complex component rrp4; PDBTitle: human nuclear exosome-mtr4 rna complex - composite map after focused2 reconstruction Phyre2 PDB 2nn6 chain I domain 2 Region: 30 - 83 Aligned: 49 Modelled: 54 Confidence: 91.5% Identity: 18% Fold: Barrel-sandwich hybrid Superfamily: Ribosomal L27 protein-like Family: ECR1 N-terminal domain-like Phyre2 PDB 4ifd chain H Region: 27 - 86 Aligned: 53 Modelled: 60 Confidence: 91.3% Identity: 19% PDB header:hydrolase/rna Chain: H: PDB Molecule:exosome complex component rrp4; PDBTitle: crystal structure of an 11-subunit eukaryotic exosome complex bound to2 rna Phyre2 PDB 2ba1 chain B Region: 29 - 84 Aligned: 49 Modelled: 56 Confidence: 91.1% Identity: 20% PDB header:rna binding protein Chain: B: PDB Molecule:archaeal exosome rna binding protein csl4; PDBTitle: archaeal exosome core Phyre2 PDB 2nn6 chain H Region: 29 - 82 Aligned: 47 Modelled: 50 Confidence: 90.4% Identity: 28% PDB header:hydrolase/transferase Chain: H: PDB Molecule:exosome complex exonuclease rrp4; PDBTitle: structure of the human rna exosome composed of rrp41, rrp45,2 rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40 Phyre2 1 c3fin0_ 2 d2zjrt1 3 c3bboX_ 4 c5mlcX_ 5 d2gycu1 6 c5o60X_ 7 c1vw4R_ 8 c4wf9T_ 9 c4v190_ 10 c2ftcO_ 11 d1v8qa_ 12 d2ba0a2 13 d2je6i2 14 d2nn6h2 15 c4ifdI_ 16 c6d6rH_ 17 d2nn6i2 18 c4ifdH_ 19 c2ba1B_ 20 c2nn6H_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70