1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	G	T	V	V	A	V	P	P	R	V	A	R	A	L	D	L	L	N	F	S	L	A	D	V	R	D	G	L	G	P	Y	L	S	I	Y	L	L	L	I	H	D	W	D	Q	A	S	I	G	F	V	M	A	V	G	G	I	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	V	A	Q	T	P	I	G	A	L	V	D	R	T	T	A	K	R	A	L	V	V	A	G	A	V	L	V	T	A	A	A	V	A	M	P	L	F	A	G	L	Y	S	I	S	V	L	Q	A	V	T	G	I	A	S	S	V	F	A	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	A	A	I	T	L	G	A	V	G	P	Q	F	F	A	R	R	I	G	R	N	E	A	F	N	H	A	G	N	A	S	A	A	G	A	T	G	A	L	A	Y	F	F	G	P	V	V	V	F	W	V	L	A	G	M	A	L	I	S
Secondary structure
SS confidence
Disorder												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	L	A	T	L	R	I	P	P	D	A	V	D	H	D	L	A	R	G	M	D	H	A	P	G	E	P	H	P	Q	P	S	R	F	T	V	L	A	H	N	R	E	L	V	I	F	G	A	A	V	V	A	F	H	F	A	N	A	A	M
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	P	L	V	G	E	L	L	A	L	H	N	R	D	E	G	T	A	L	M	S	S	C	I	V	A	A	Q	V	V	M	V	P	V	A	Y	V	V	G	T	R	A	D	A	W	G	R	K	P	I	F	L	V	G	F	A	V	L	T	A
Secondary structure
SS confidence
Disorder											?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	G	F	L	Y	T	L	S	D	N	S	Y	W	L	V	G	V	Q	L	L	D	G	I	G	A	G	I	F	G	A	L	F	P	L	V	V	Q	D	V	T	H	G	T	G	H	F	N	I	S	L	G	A	V	T	T	A	T	G	I	G
Secondary structure
SS confidence
Disorder																																								?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.
Sequence		A	A	L	S	N	L	V	A	G	W	I	V	V	V	A	G	Y	D	A	A	F	M	S	L	G	A	L	A	G	A	G	F	L	L	Y	L	V	A	M	P	E	T	V	D	S	D	V	R	V	R	S	R	P	T	L	G	G	K
Secondary structure
SS confidence
Disorder																																										?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 79%) Beta strand ( 0%) TM helix ( 64%) (View membrane topology prediction)

Rank Aligned region

PDB 6e9o chain A Region: 9 - 404 Aligned: 389 Modelled: 396 Confidence: 100.0% Identity: 14% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 3wdo chain A Region: 2 - 418 Aligned: 406 Modelled: 417 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:mfs transporter; PDBTitle: structure of e. coli yajr transporter Phyre2 PDB 4lds chain B Region: 13 - 403 Aligned: 390 Modelled: 391 Confidence: 100.0% Identity: 14% PDB header:transport protein, membrane protein Chain: B: PDB Molecule:bicyclomycin resistance protein tcab; PDBTitle: the inward-facing structure of the glucose transporter from2 staphylococcus epidermidis Phyre2 PDB 4j05 chain A Region: 9 - 418 Aligned: 407 Modelled: 410 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:phosphate transporter; PDBTitle: crystal structure of a eukaryotic phosphate transporter Phyre2 PDB 1pv7 chain A Region: 8 - 416 Aligned: 408 Modelled: 409 Confidence: 100.0% Identity: 12% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: LacY-like proton/sugar symporter Phyre2 PDB 1pv7 chain B Region: 8 - 416 Aligned: 408 Modelled: 409 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: B: PDB Molecule:lactose permease; PDBTitle: crystal structure of lactose permease with tdg Phyre2 PDB 1pw4 chain A Region: 10 - 412 Aligned: 400 Modelled: 403 Confidence: 100.0% Identity: 11% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: Glycerol-3-phosphate transporter Phyre2 PDB 6h7d chain A Region: 13 - 418 Aligned: 403 Modelled: 406 Confidence: 100.0% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:sugar transport protein 10; PDBTitle: crystal structure of a. thaliana sugar transport protein 10 in complex2 with glucose in the outward occluded state Phyre2 PDB 6gs7 chain A Region: 10 - 404 Aligned: 394 Modelled: 395 Confidence: 100.0% Identity: 14% PDB header:membrane protein Chain: A: PDB Molecule:dipeptide and tripeptide permease a; PDBTitle: crystal structure of peptide transporter dtpa-nanobody in glycine2 buffer Phyre2 PDB 4iky chain A Region: 10 - 404 Aligned: 392 Modelled: 395 Confidence: 100.0% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:di-tripeptide abc transporter (permease); PDBTitle: crystal structure of peptide transporter pot (e310q mutant) in complex2 with sulfate Phyre2 PDB 6exs chain A Region: 10 - 404 Aligned: 392 Modelled: 395 Confidence: 100.0% Identity: 13% PDB header:membrane protein Chain: A: PDB Molecule:peptide abc transporter permease; PDBTitle: crystal structure of a pot family transporter in complex with2 thioalcohol conjugated peptide. Phyre2 PDB 4zp0 chain A Region: 13 - 400 Aligned: 377 Modelled: 381 Confidence: 100.0% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:multidrug transporter mdfa; PDBTitle: crystal structure of e. coli multidrug transporter mdfa in complex2 with deoxycholate Phyre2 PDB 4cl5 chain B Region: 11 - 408 Aligned: 396 Modelled: 398 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: B: PDB Molecule:nitrate transporter 1.1; PDBTitle: crystal structure of the nitrate transporter nrt1.1 from2 arabidopsis thaliana in complex with nitrate. Phyre2 PDB 4w6v chain A Region: 10 - 404 Aligned: 393 Modelled: 395 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:di-/tripeptide transporter; PDBTitle: crystal structure of a peptide transporter from yersinia2 enterocolitica at 3 a resolution Phyre2 PDB 3o7p chain A Region: 11 - 402 Aligned: 386 Modelled: 392 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:l-fucose-proton symporter; PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a) Phyre2 PDB 4aps chain B Region: 10 - 398 Aligned: 386 Modelled: 389 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: B: PDB Molecule:di-or tripeptide h+ symporter; PDBTitle: crystal structure of a pot family peptide transporter in an inward2 open conformation. Phyre2 PDB 5c65 chain A Region: 8 - 416 Aligned: 408 Modelled: 409 Confidence: 100.0% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 2, facilitated glucose transporter PDBTitle: structure of the human glucose transporter glut3 / slc2a3 Phyre2 PDB 6g9x chain B Region: 13 - 404 Aligned: 365 Modelled: 372 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: B: PDB Molecule:major facilitator superfamily mfs_1; PDBTitle: crystal structure of a mfs transporter at 2.54 angstroem resolution Phyre2 PDB 6ei3 chain A Region: 10 - 412 Aligned: 402 Modelled: 403 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:proton-dependent oligopeptide transporter family protein; PDBTitle: crystal structure of auto inhibited pot family peptide transporter Phyre2 PDB 4ybq chain B Region: 13 - 412 Aligned: 398 Modelled: 400 Confidence: 100.0% Identity: 11% PDB header:transport protein/immune system Chain: B: PDB Molecule:solute carrier family 2, facilitated glucose transporter PDBTitle: rat glut5 with fv in the outward-open form Phyre2 1 c6e9oA_ 2 c3wdoA_ 3 c4ldsB_ 4 c4j05A_ 5 d1pv7a_ 6 c1pv7B_ 7 d1pw4a_ 8 c6h7dA_ 9 c6gs7A_ 10 c4ikyA_ 11 c6exsA_ 12 c4zp0A_ 13 c4cl5B_ 14 c4w6vA_ 15 c3o7pA_ 16 c4apsB_ 17 c5c65A_ 18 c6g9xB_ 19 c6ei3A_ 20 c4ybqB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54