1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	P	T	S	S	S	V	A	S	E	L	L	M	P	W	P	S	A	A	A	S	G	V	V	G	W	R	T	T	A	T	A	S	Q	R	Y	H	R	P	M	S	D	T	P	F	A	E	P	Y	P	E	Q	R	P	P	W	G	V	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																								?	?	?	?											?	?	?	?					?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	P	G	W	D	G	S	S	R	P	A	P	S	T	T	P	R	S	P	G	R	W	S	L	V	A	A	L	A	L	A	V	V	S	L	G	V	G	I	V	G	W	F	H	R	Q	P	H	D	K	P	S	P	A	P	S	A	P	T	F
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																										?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	S	Q	Q	I	S	D	A	K	E	N	V	C	A	A	H	R	I	V	R	Q	A	A	V	L	N	T	N	Q	A	N	P	V	P	G	D	P	T	G	D	L	A	V	A	A	N	A	R	L	A	L	Y	S	G	G	D	Y	L	L	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?														?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Sequence		R	L	T	A	E	P	A	T	P	A	E	L	R	D	A	V	R	S	L	A	N	A	L	Q	E	L	A	V	N	Y	L	A	G	A	P	D	S	V	V	T	P	L	R	L	A	L	E	R	D	T	R	A	V	D	P	L	C	V
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?																												?												?			?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 38%) Alpha helix ( 56%) Beta strand ( 1%) TM helix ( 9%) (View membrane topology prediction)

Rank Aligned region

PDB 1jmt chain B Region: 57 - 65 Aligned: 9 Modelled: 9 Confidence: 48.4% Identity: 67% PDB header:rna binding protein Chain: B: PDB Molecule:splicing factor u2af 65 kda subunit; PDBTitle: x-ray structure of a core u2af65/u2af35 heterodimer Phyre2 PDB 6hwh chain X Region: 34 - 103 Aligned: 53 Modelled: 54 Confidence: 27.8% Identity: 17% PDB header:electron transport Chain: X: PDB Molecule:cytochrome c oxidase polypeptide 4; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 4ng2 chain E Region: 35 - 60 Aligned: 26 Modelled: 26 Confidence: 26.5% Identity: 35% PDB header:transcription regulator Chain: E: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of lasr lbd-qsla complex from pseudomonas aeruginosa Phyre2 PDB 2y69 chain Q Region: 76 - 105 Aligned: 30 Modelled: 30 Confidence: 18.9% Identity: 20% PDB header:electron transport Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1; PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular oxygen Phyre2 PDB 6hu9 chain E Region: 78 - 112 Aligned: 35 Modelled: 35 Confidence: 18.1% Identity: 17% PDB header:oxidoreductase/electron transport Chain: E: PDB Molecule:cytochrome b-c1 complex subunit rieske, mitochondrial; PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae Phyre2 PDB 1v54 chain D Region: 76 - 105 Aligned: 30 Modelled: 30 Confidence: 16.4% Identity: 20% Fold: Single transmembrane helix Superfamily: Mitochondrial cytochrome c oxidase subunit IV Family: Mitochondrial cytochrome c oxidase subunit IV Phyre2 PDB 4dlp chain B Region: 53 - 66 Aligned: 14 Modelled: 14 Confidence: 14.0% Identity: 36% PDB header:ligase Chain: B: PDB Molecule:aminoacyl-trna synthetase, class i:aminoacyl-trna PDBTitle: crystal structure of methionyl-trna synthetase metrs from brucella2 melitensis bound to selenomethionine Phyre2 PDB 1w8x chain P Region: 99 - 120 Aligned: 22 Modelled: 22 Confidence: 13.6% Identity: 23% PDB header:virus Chain: P: PDB Molecule:protein p16; PDBTitle: structural analysis of prd1 Phyre2 PDB 2fiq chain A domain 1 Region: 132 - 203 Aligned: 57 Modelled: 72 Confidence: 11.4% Identity: 32% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: GatZ-like Phyre2 PDB 1zza chain A Region: 85 - 103 Aligned: 19 Modelled: 19 Confidence: 9.8% Identity: 32% PDB header:membrane protein Chain: A: PDB Molecule:stannin; PDBTitle: solution nmr structure of the membrane protein stannin Phyre2 PDB 4e6n chain B Region: 14 - 58 Aligned: 45 Modelled: 45 Confidence: 8.5% Identity: 20% PDB header:protein binding Chain: B: PDB Molecule:methyltransferase type 12; PDBTitle: crystal structure of bacterial pnkp-c/hen1-n heterodimer Phyre2 PDB 4ard chain A Region: 170 - 179 Aligned: 10 Modelled: 10 Confidence: 8.4% Identity: 70% PDB header:viral protein Chain: A: PDB Molecule:capsid protein p27; PDBTitle: structure of the immature retroviral capsid at 8a resolution by cryo-2 electron microscopy Phyre2 PDB 1mp9 chain A domain 1 Region: 188 - 208 Aligned: 21 Modelled: 21 Confidence: 8.2% Identity: 24% Fold: TBP-like Superfamily: TATA-box binding protein-like Family: TATA-box binding protein (TBP), C-terminal domain Phyre2 PDB 6c48 chain E Region: 177 - 207 Aligned: 26 Modelled: 31 Confidence: 7.9% Identity: 38% PDB header:cell cycle/dna binding Chain: E: PDB Molecule:protein lin-52 homolog; PDBTitle: crystal structure of b-myb-lin9-lin52 complex Phyre2 PDB 1ais chain A domain 1 Region: 188 - 208 Aligned: 21 Modelled: 21 Confidence: 7.4% Identity: 29% Fold: TBP-like Superfamily: TATA-box binding protein-like Family: TATA-box binding protein (TBP), C-terminal domain Phyre2 PDB 2jmv chain A Region: 110 - 120 Aligned: 11 Modelled: 11 Confidence: 7.2% Identity: 55% PDB header:antiviral protein Chain: A: PDB Molecule:scytovirin; PDBTitle: solution structure of scytovirin refined against residual2 dipolar couplings Phyre2 PDB 2ky8 chain A Region: 52 - 64 Aligned: 13 Modelled: 13 Confidence: 6.6% Identity: 38% PDB header:transcription/dna Chain: A: PDB Molecule:methyl-cpg-binding domain protein 2; PDBTitle: solution structure and dynamic analysis of chicken mbd2 methyl binding2 domain bound to a target methylated dna sequence Phyre2 PDB 5v8k chain A Region: 172 - 182 Aligned: 11 Modelled: 11 Confidence: 6.6% Identity: 36% PDB header:photosynthesis Chain: A: PDB Molecule:p800 reaction center core protein; PDBTitle: homodimeric reaction center of h. modesticaldum Phyre2 PDB 6hum chain I Region: 39 - 66 Aligned: 25 Modelled: 28 Confidence: 6.3% Identity: 24% PDB header:proton transport Chain: I: PDB Molecule:nad(p)h-quinone oxidoreductase subunit i; PDBTitle: structure of the photosynthetic complex i from thermosynechococcus2 elongatus Phyre2 PDB 3ajb chain B Region: 110 - 115 Aligned: 6 Modelled: 6 Confidence: 6.3% Identity: 100% PDB header:protein transport Chain: B: PDB Molecule:peroxisomal biogenesis factor 19; PDBTitle: crystal structure of human pex3p in complex with n-terminal pex19p2 peptide Phyre2 1 c1jmtB_ 2 c6hwhX_ 3 c4ng2E_ 4 c2y69Q_ 5 c6hu9e_ 6 d1v54d_ 7 c4dlpB_ 8 c1w8xP_ 9 d2fiqa1 10 c1zzaA_ 11 c4e6nB_ 12 c4ardA_ 13 d1mp9a1 14 c6c48E_ 15 d1aisa1 16 c2jmvA_ 17 c2ky8A_ 18 c5v8kA_ 19 c6humI_ 20 c3ajbB_ 21 22 23 24 25 26