1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	E	R	G	L	W	L	P	D	P	A	H	R	A	D	L	A	T	F	V	D	H	A	L	R	L	D	D	A	A	V	I	R	I	R	A	R	S	T	G	L	L	S	A	W	V	A	T	G	F	D	V	L	A	S	R	V	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																	?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	K	V	R	P	D	D	L	S	V	A	A	R	S	L	A	H	G	L	A	T	T	D	A	S	G	Y	V	D	P	G	Y	S	M	D	S	A	W	R	G	G	L	P	P	E	S	G	F	T	Y	L	D	D	V	P	A	R	V	M	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?																?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	L	A	H	R	G	A	R	L	A	K	E	H	G	S	S	A	G	P	P	V	S	L	L	D	Q	E	V	I	Q	V	S	S	A	D	V	V	V	G	L	P	M	R	C	V	F	A	L	T	A	M	G	F	L	P	Q	S	A	E	T
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?						?	?		?																				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.
Sequence		I	S	A	D	E	L	I	R	V	R	I	S	P	A	W	L	R	L	D	A	R	F	G	S	V	Y	R	H	R	G	H	A	A	L	V	L	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?								?																		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 34%) Alpha helix ( 24%) Beta strand ( 29%)

Rank Aligned region

PDB 1avy chain A Region: 163 - 200 Aligned: 34 Modelled: 38 Confidence: 45.9% Identity: 26% PDB header:coiled coil Chain: A: PDB Molecule:fibritin; PDBTitle: fibritin deletion mutant m (bacteriophage t4) Phyre2 PDB 3g80 chain B Region: 4 - 22 Aligned: 19 Modelled: 19 Confidence: 25.3% Identity: 32% PDB header:viral protein Chain: B: PDB Molecule:protein b2; PDBTitle: nodamura virus protein b2, rna-binding domain Phyre2 PDB 1rfo chain C Region: 172 - 200 Aligned: 25 Modelled: 29 Confidence: 22.9% Identity: 24% PDB header:viral protein Chain: C: PDB Molecule:whisker antigen control protein; PDBTitle: trimeric foldon of the t4 phagehead fibritin Phyre2 PDB 2lp7 chain C Region: 172 - 204 Aligned: 29 Modelled: 33 Confidence: 17.6% Identity: 28% PDB header:viral protein Chain: C: PDB Molecule:envelope glycoprotein; PDBTitle: structure of gp41-m-mat, a membrane associated mper trimer from hiv-12 gp41. Phyre2 PDB 1aa0 chain A Region: 163 - 200 Aligned: 34 Modelled: 38 Confidence: 17.4% Identity: 26% PDB header:attachment protein Chain: A: PDB Molecule:fibritin; PDBTitle: fibritin deletion mutant e (bacteriophage t4) Phyre2 PDB 1ox3 chain A Region: 162 - 200 Aligned: 35 Modelled: 39 Confidence: 13.7% Identity: 17% PDB header:chaperone Chain: A: PDB Molecule:fibritin; PDBTitle: crystal structure of mini-fibritin Phyre2 PDB 1k4n chain A Region: 103 - 114 Aligned: 12 Modelled: 12 Confidence: 11.6% Identity: 25% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Hypothetical protein YecM (EC4020) Phyre2 PDB 2knr chain A Region: 6 - 30 Aligned: 25 Modelled: 25 Confidence: 10.4% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atc0905; PDBTitle: solution structure of protein atu0922 from a. tumefaciens. northeast2 structural genomics consortium target att13. ontario center for3 structural proteomics target atc0905 Phyre2 PDB 5o31 chain Z Region: 102 - 113 Aligned: 12 Modelled: 12 Confidence: 9.8% Identity: 33% PDB header:oxidoreductase Chain: Z: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: mitochondrial complex i in the deactive state Phyre2 PDB 6gcs chain W Region: 102 - 112 Aligned: 11 Modelled: 11 Confidence: 9.1% Identity: 36% PDB header:oxidoreductase Chain: W: PDB Molecule:nb6m subunit; PDBTitle: cryo-em structure of respiratory complex i from yarrowia lipolytica Phyre2 PDB 2mck chain A Region: 192 - 199 Aligned: 8 Modelled: 8 Confidence: 8.9% Identity: 75% PDB header:hydrolase Chain: A: PDB Molecule:polyprotein; PDBTitle: backbone 1h, 13c, and 15n chemical shift assignments for murine2 norovirus cr6 ns1/2 protein Phyre2 PDB 5lnk chain Q Region: 102 - 112 Aligned: 11 Modelled: 11 Confidence: 7.7% Identity: 36% PDB header:oxidoreductase Chain: Q: PDB Molecule: PDBTitle: entire ovine respiratory complex i Phyre2 PDB 1gsm chain A domain 1 Region: 191 - 217 Aligned: 27 Modelled: 27 Confidence: 7.3% Identity: 33% Fold: Immunoglobulin-like beta-sandwich Superfamily: Immunoglobulin Family: I set domains Phyre2 PDB 1kbl chain A domain 2 Region: 188 - 207 Aligned: 20 Modelled: 20 Confidence: 6.7% Identity: 20% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: Pyruvate phosphate dikinase, central domain Phyre2 PDB 2gqc chain A Region: 4 - 31 Aligned: 28 Modelled: 28 Confidence: 6.6% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:rhomboid intramembrane protease; PDBTitle: solution structure of the n-terminal domain of rhomboid intramembrane2 protease from p. aeruginosa Phyre2 PDB 1v1c chain A Region: 101 - 108 Aligned: 8 Modelled: 8 Confidence: 6.6% Identity: 25% PDB header:sh3-domain Chain: A: PDB Molecule:obscurin; PDBTitle: solution structure of the sh3 domain of obscurin Phyre2 PDB 3mwz chain A Region: 105 - 130 Aligned: 26 Modelled: 26 Confidence: 6.3% Identity: 15% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:sialostatin l2; PDBTitle: crystal structure of the selenomethionine derivative of the l 22,47,2 100 m mutant of sialostatin l2 Phyre2 PDB 1r7c chain A Region: 192 - 197 Aligned: 6 Modelled: 6 Confidence: 5.6% Identity: 67% PDB header:membrane protein Chain: A: PDB Molecule:genome polyprotein; PDBTitle: nmr structure of the membrane anchor domain (1-31) of the2 nonstructural protein 5a (ns5a) of hepatitis c virus3 (minimized average structure, sample in 50% tfe) Phyre2 PDB 1r7g chain A Region: 192 - 197 Aligned: 6 Modelled: 6 Confidence: 5.6% Identity: 67% PDB header:membrane protein Chain: A: PDB Molecule:genome polyprotein; PDBTitle: nmr structure of the membrane anchor domain (1-31) of the2 nonstructural protein 5a (ns5a) of hepatitis c virus3 (minimized average structure, sample in 100mm dpc) Phyre2 PDB 4goq chain D Region: 6 - 30 Aligned: 25 Modelled: 24 Confidence: 5.5% Identity: 20% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a duf1491 family protein (cc_1065) from2 caulobacter crescentus cb15 at 1.87 a resolution Phyre2 1 c1avyA_ 2 c3g80B_ 3 c1rfoC_ 4 c2lp7C_ 5 c1aa0A_ 6 c1ox3A_ 7 d1k4na_ 8 c2knrA_ 9 c5o31Z_ 10 c6gcsW_ 11 c2mckA_ 12 c5lnkq_ 13 d1gsma1 14 d1kbla2 15 c2gqcA_ 16 c1v1cA_ 17 c3mwzA_ 18 c1r7cA_ 19 c1r7gA_ 20 c4goqD_ 21 22 23