Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD2492_(-)_2807288_2808040
DateWed Aug 7 12:50:12 BST 2019
Unique Job ID2e0022f3a518a786
SequenceMSRRIINEFG ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:48.973 Y:50.777 Z:53.380
Model (left) based on template c3clbA_
Top template information
PDB header:oxidoreductase, transferase
Chain: A: PDB Molecule:dhfr-ts;
PDBTitle: structure of bifunctional tcdhfr-ts in complex with tmq
Confidence and coverage
Confidence:100.0% Coverage: 84%
210 residues ( 84% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3clbA_
100.0 18
PDB header:oxidoreductase, transferase
Chain: A: PDB Molecule:dhfr-ts;
PDBTitle: structure of bifunctional tcdhfr-ts in complex with tmq
2d2g8oa1
100.0 19
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
3d1f28a_
100.0 16
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
4d1seja2
100.0 20
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
5c2oipE_
100.0 20
PDB header:transferase, oxidoreductase
Chain: E: PDB Molecule:chain a, crystal structure of dhfr;
PDBTitle: crystal structure of the s290g active site mutant of ts-dhfr from2 cryptosporidium hominis
6c2aazG_
100.0 16
PDB header:transferase
Chain: G: PDB Molecule:thymidylate synthase;
PDBTitle: cryptococcus neoformans thymidylate synthase complexed with substrate2 and an antifolate
7c3jsuA_
100.0 15
PDB header:oxidoreductase, transferase
Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase;
PDBTitle: quadruple mutant(n51i+c59r+s108n+i164l) plasmodium falciparum2 dihydrofolate reductase-thymidylate synthase(pfdhfr-ts) complexed3 with qn254, nadph, and dump
8c3qj7D_
100.0 18
PDB header:transferase
Chain: D: PDB Molecule:thymidylate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis thymidylate2 synthase (thya) bound to dump
9c4eckB_
100.0 16
PDB header:transferase, oxidoreductase
Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate synthase;
PDBTitle: crystal structure of the toxoplasma gondii ts-dhfr
10d1qzfa2
100.0 19
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
11c3k2hA_
100.0 19
PDB header:transferase
Chain: A: PDB Molecule:dihydrofolate reductase/thymidylate synthase;
PDBTitle: co-crystal structure of dihydrofolate reductase/thymidylate synthase2 from babesia bovis with dump, pemetrexed and nadp
12c6aujC_
100.0 22
PDB header:transferase
Chain: C: PDB Molecule:thymidylate synthase;
PDBTitle: crystal structure of thymidylate synthase from elizabethkingia2 anophelis nuhp1
13c4g9uD_
100.0 17
PDB header:transferase
Chain: D: PDB Molecule:thymidylate synthase;
PDBTitle: crystal structure of trichinella spiralis thymidylate synthase2 complexed with dump
14d1j3kc_
100.0 15
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
15d1bkpa_
100.0 15
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
16c4iswB_
100.0 18
PDB header:transferase
Chain: B: PDB Molecule:thymidylate synthase;
PDBTitle: crystal structure of phosphorylated c.elegans thymidylate synthase in2 complex with dump
17c4dq1A_
100.0 22
PDB header:transferase
Chain: A: PDB Molecule:thymidylate synthase;
PDBTitle: thymidylate synthase from staphylococcus aureus.
18d1tswa_
100.0 25
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
19d2tsra_
100.0 17
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
20c5b6dB_
100.0 19
PDB header:transferase
Chain: B: PDB Molecule:cmp 5-hydroxymethylase;
PDBTitle: crystal structure of cytidine monophosphate hydroxymethylase mila with2 cmp
21c3ix6B_
not modelled 100.0 20
PDB header:transferase
Chain: B: PDB Molecule:thymidylate synthase;
PDBTitle: crystal structure of thymidylate synthase thya from brucella2 melitensis
22c3v8hB_
not modelled 100.0 17
PDB header:transferase
Chain: B: PDB Molecule:thymidylate synthase;
PDBTitle: crystal structure of thymidylate synthase from burkholderia2 thailandensis
23d1hvya_
not modelled 100.0 17
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
24d1tisa_
not modelled 100.0 17
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
25c3kgbA_
not modelled 100.0 19
PDB header:transferase
Chain: A: PDB Molecule:thymidylate synthase 1/2;
PDBTitle: crystal structure of thymidylate synthase 1/2 from encephalitozoon2 cuniculi at 2.2 a resolution
26c1hw4A_
not modelled 100.0 17
PDB header:transferase
Chain: A: PDB Molecule:thymidylate synthase;
PDBTitle: structure of thymidylate synthase suggests advantages of chemotherapy2 with noncompetitive inhibitors
27c1hw3A_
not modelled 100.0 17
PDB header:transferase
Chain: A: PDB Molecule:thymidylate synthase;
PDBTitle: structure of human thymidylate synthase suggests advantages of2 chemotherapy with noncompetitive inhibitors
28c3egyX_
not modelled 100.0 18
PDB header:transferase
Chain: X: PDB Molecule:thymidylate synthase;
PDBTitle: crystal structure of human thymidyalte synthase a191k with loop 181-2 197 stabilized in the inactive conformation
29d1b5ea_
not modelled 100.0 13
Fold:Thymidylate synthase/dCMP hydroxymethylase
Superfamily:Thymidylate synthase/dCMP hydroxymethylase
Family:Thymidylate synthase/dCMP hydroxymethylase
30c2bn5A_
not modelled 33.5 15
PDB header:nuclear protein
Chain: A: PDB Molecule:psi;
PDBTitle: p-element somatic inhibitor protein complex with u1-70k2 proline-rich peptide
31c2bn6A_
not modelled 26.1 15
PDB header:nuclear protein
Chain: A: PDB Molecule:psi;
PDBTitle: p-element somatic inhibitor protein
32d2gnoa2
not modelled 25.4 16
Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
33c2gnoA_
not modelled 16.2 16
PDB header:replication
Chain: A: PDB Molecule:dna polymerase iii, gamma subunit-related protein;
PDBTitle: crystal structure of a dna polymerase iii, gamma subunit-related2 protein (tm0771) from thermotoga maritima msb8 at 2.00 a resolution
34c4je3B_
not modelled 11.5 13
PDB header:cell cycle
Chain: B: PDB Molecule:central kinetochore subunit chl4;
PDBTitle: an iml3-chl4 heterodimer links the core centromere to factors required2 for accurate chromosome segregation
35c2vsvB_
not modelled 10.9 19
PDB header:protein binding
Chain: B: PDB Molecule:rhophilin-2;
PDBTitle: crystal structure of the pdz domain of human rhophilin-2
36c4tkzA_
not modelled 10.7 25
PDB header:transferase
Chain: A: PDB Molecule:putative uncharacterized protein gbs1890;
PDBTitle: crystal structure of phosphotransferase system component eiia from2 streptococcus agalactiae
37c3fgrA_
not modelled 10.5 13
PDB header:hydrolase
Chain: A: PDB Molecule:putative phospholipase b-like 2 28 kda form;
PDBTitle: two chain form of the 66.3 kda protein at 1.8 angstroem
38d1r8ea2
not modelled 9.1 12
Fold:Probable bacterial effector-binding domain
Superfamily:Probable bacterial effector-binding domain
Family:Multidrug-binding domain of transcription activator BmrR
39c2wzoA_
not modelled 8.4 18
PDB header:cell cycle
Chain: A: PDB Molecule:transforming growth factor beta regulator 1;
PDBTitle: the structure of the fyr domain
40d1xoub_
not modelled 8.3 28
Fold:EspA/CesA-like
Superfamily:EspA/CesA-like
Family:EspA chaperone CesA
41c6fmgC_
not modelled 8.0 33
PDB header:transferase
Chain: C: PDB Molecule:pts system mannose-specific transporter subunit iiab;
PDBTitle: structure of the mannose transporter iia domain from streptococcus2 pneumoniae
42c4fp9F_
not modelled 7.9 14
PDB header:transferase
Chain: F: PDB Molecule:methyltransferase nsun4;
PDBTitle: human mterf4-nsun4 protein complex
43d1ueza_
not modelled 7.7 29
Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
44c3lfhF_
not modelled 7.7 17
PDB header:transferase
Chain: F: PDB Molecule:phosphotransferase system, mannose/fructose-specific
PDBTitle: crystal structure of manxa from thermoanaerobacter tengcongensis
45d1pdoa_
not modelled 7.3 27
Fold:PTS system fructose IIA component-like
Superfamily:PTS system fructose IIA component-like
Family:EIIA-man component-like
46c6cjdA_
not modelled 7.1 40
PDB header:protein binding
Chain: A: PDB Molecule:putative cytoplasmic protein;
PDBTitle: nmr structure of salmonella type iii secretion system protein orgc
47c1sqgA_
not modelled 7.1 23
PDB header:transferase
Chain: A: PDB Molecule:sun protein;
PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution
48c2lifA_
not modelled 7.1 20
PDB header:viral protein, membrane protein
Chain: A: PDB Molecule:core protein p21;
PDBTitle: solution structure of kkgf
49c3mtqA_
not modelled 7.0 17
PDB header:transferase
Chain: A: PDB Molecule:putative phosphoenolpyruvate-dependent sugar
PDBTitle: crystal structure of a putative phosphoenolpyruvate-dependent sugar2 phosphotransferase system (pts) permease (kpn_04802) from klebsiella3 pneumoniae subsp. pneumoniae mgh 78578 at 1.70 a resolution
50d2ezla_
not modelled 6.6 3
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Recombinase DNA-binding domain
51c1piwA_
not modelled 6.3 14
PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical zinc-type alcohol dehydrogenase-
PDBTitle: apo and holo structures of an nadp(h)-dependent cinnamyl2 alcohol dehydrogenase from saccharomyces cerevisiae
52d1wgna_
not modelled 5.9 9
Fold:RuvA C-terminal domain-like
Superfamily:UBA-like
Family:UBA domain
53c5t3uA_
not modelled 5.7 19
PDB header:transport protein
Chain: A: PDB Molecule:pts system, iia component;
PDBTitle: crystal structure of the pts iia protein associated with the fucose2 utilization operon from streptococcus pneumoniae
54d1pi1a_
not modelled 5.6 23
Fold:Bromodomain-like
Superfamily:Mob1/phocein
Family:Mob1/phocein
55c2lndA_
not modelled 5.5 24
PDB header:de novo protein
Chain: A: PDB Molecule:de novo designed protein, pfk fold;
PDBTitle: solution nmr structure of de novo designed protein, pfk fold,2 northeast structural genomics consortium target or134
56c3j47O_
not modelled 5.5 6
PDB header:protein binding
Chain: O: PDB Molecule:26s proteasome regulatory subunit rpn9;
PDBTitle: formation of an intricate helical bundle dictates the assembly of the2 26s proteasome lid
57c3iprC_
not modelled 5.5 13
PDB header:transferase
Chain: C: PDB Molecule:pts system, iia component;
PDBTitle: crystal structure of the enterococcus faecalis gluconate2 specific eiia phosphotransferase system component
58d1j3wa_
not modelled 5.3 10
Fold:Profilin-like
Superfamily:Roadblock/LC7 domain
Family:Roadblock/LC7 domain
59c6iczX_
not modelled 5.3 16
PDB header:splicing
Chain: X: PDB Molecule:prkr-interacting protein 1;
PDBTitle: cryo-em structure of a human post-catalytic spliceosome (p complex) at2 3.0 angstrom
60c3dhiA_
not modelled 5.2 14
PDB header:oxidoreductase
Chain: A: PDB Molecule:toluene 4-monooxygenase hydroxylase alpha subunit;
PDBTitle: crystal structure of reduced toluene 4-monoxygenase hydroxylase2 complexed with effector protein
61c5yf4A_
not modelled 5.1 15
PDB header:protein binding
Chain: A: PDB Molecule:mob-like protein phocein;
PDBTitle: a kinase complex mst4-mob4
62c4q9aA_
not modelled 5.0 17
PDB header:hydrolase
Chain: A: PDB Molecule:tat pathway signal sequence domain protein;
PDBTitle: crystal structure of a putative gdsl-like lipase (parmer_00689) from2 parabacteroides merdae atcc 43184 at 2.86 a resolution
63d1eyra_
not modelled 5.0 8
Fold:Nucleotide-diphospho-sugar transferases
Superfamily:Nucleotide-diphospho-sugar transferases
Family:Cytidylytransferase

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