Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD2496c_(pdhB)_2809946_2810992
DateWed Aug 7 12:50:12 BST 2019
Unique Job IDda5ad71a0d4b507e
SequenceMTQIADRPAR ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:59.845 Y:50.475 Z:47.909
Model (left) based on template c1olsB_
Top template information
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit;
PDBTitle: roles of his291-alpha and his146-beta' in the reductive acylation2 reaction catalyzed by human branched-chain alpha-ketoacid3 dehydrogenase
Confidence and coverage
Confidence:100.0% Coverage: 93%
325 residues ( 93% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1olsB_



100.0 38
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit;
PDBTitle: roles of his291-alpha and his146-beta' in the reductive acylation2 reaction catalyzed by human branched-chain alpha-ketoacid3 dehydrogenase
2c1ni4D_



100.0 34
PDB header:oxidoreductase
Chain: D: PDB Molecule:pyruvate dehydrogenase e1 component: beta
PDBTitle: human pyruvate dehydrogenase
3c2bp7F_



100.0 46
PDB header:oxidoreductase
Chain: F: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit;
PDBTitle: new crystal form of the pseudomonas putida branched-chain2 dehydrogenase (e1)
4c3dufD_



100.0 48
PDB header:oxidoreductase/transferase
Chain: D: PDB Molecule:pyruvate dehydrogenase e1 component subunit beta;
PDBTitle: snapshots of catalysis in the e1 subunit of the pyruvate2 dehydrogenase multi-enzyme complex
5c1um9D_



100.0 48
PDB header:oxidoreductase
Chain: D: PDB Molecule:2-oxo acid dehydrogenase beta subunit;
PDBTitle: branched-chain 2-oxo acid dehydrogenase (e1) from thermus2 thermophilus hb8 in apo-form
6c1ik6A_



100.0 48
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate dehydrogenase;
PDBTitle: 3d structure of the e1beta subunit of pyruvate2 dehydrogenase from the archeon pyrobaculum aerophilum
7c6ouwA_



100.0 19
PDB header:transferase
Chain: A: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxps) from deinococcus2 radiodurans with enamine intermediate bound
8c2o1xA_



100.0 19
PDB header:transferase
Chain: A: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from deinococcus2 radiodurans
9c2o1sC_



100.0 22
PDB header:transferase
Chain: C: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from2 escherichia coli
10c3mosA_



100.0 18
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: the structure of human transketolase
11c2r8pA_



100.0 13
PDB header:transferase
Chain: A: PDB Molecule:transketolase 1;
PDBTitle: transketolase from e. coli in complex with substrate d-fructose-6-2 phosphate
12c1tkcA_



100.0 14
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: specificity of coenzyme binding in thiamin diphosphate2 dependent enzymes: crystal structures of yeast3 transketolase in complex with analogs of thiamin4 diphosphate
13c5nd5A_



100.0 15
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase from chlamydomonas reinhardtii in2 complex with tpp and mg2+
14c4c7vA_



100.0 11
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: apo transketolase from lactobacillus salivarius at 2.2a resolution
15c3rimA_



100.0 14
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of mycobacterium tuberculosis transketolase2 (rv1449c)
16c3hylB_



100.0 14
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase from bacillus anthracis
17c5hgxA_



100.0 14
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase mutant - h261f from pichia stipitis
18c1r9jB_



100.0 15
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: transketolase from leishmania mexicana
19c3komB_



100.0 15
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: crystal structure of apo transketolase from francisella tularensis
20c3uk1A_



100.0 14
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of a transketolase from burkholderia thailandensis2 with an oxidized cysteinesulfonic acid in the active site
21c2e6kB_



not modelled 100.0 14
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: x-ray structure of thermus thermopilus hb8 tt0505
22c1itzC_



not modelled 100.0 13
PDB header:transferase
Chain: C: PDB Molecule:transketolase;
PDBTitle: maize transketolase in complex with tpp
23c5vrbB_



not modelled 100.0 15
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: crystal structure of a transketolase from neisseria gonorrhoeae
24c3m7iA_



not modelled 100.0 13
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase in complex with thiamine2 diphosphate, ribose-5-phosphate(pyranose form) and magnesium ion
25d1qs0b1



not modelled 100.0 45
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
26d2ozlb1



not modelled 100.0 33
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
27d1w85b1



not modelled 100.0 53
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
28d1umdb1



not modelled 100.0 55
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
29c2g28A_



not modelled 100.0 10
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate dehydrogenase e1 component;
PDBTitle: e. coli pyruvate dehydrogenase h407a variant2 phosphonolactylthiamin diphosphate complex
30d2bfdb1



not modelled 100.0 40
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
31c2xt6B_



not modelled 100.0 18
PDB header:lyase
Chain: B: PDB Molecule:2-oxoglutarate decarboxylase;
PDBTitle: crystal structure of mycobacterium smegmatis alpha-ketoglutarate2 decarboxylase homodimer (orthorhombic form)
32c2yicC_



not modelled 100.0 18
PDB header:lyase
Chain: C: PDB Molecule:2-oxoglutarate decarboxylase;
PDBTitle: crystal structure of the suca domain of mycobacterium smegmatis2 alpha-ketoglutarate decarboxylase (triclinic form)
33c2jgdA_



not modelled 100.0 20
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-oxoglutarate dehydrogenase e1 component;
PDBTitle: e. coli 2-oxoglutarate dehydrogenase (e1o)
34c4qoyC_



not modelled 100.0 10
PDB header:oxidoreductase
Chain: C: PDB Molecule:pyruvate dehydrogenase e1 component;
PDBTitle: novel binding motif and new flexibility revealed by structural2 analysis of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase3 sub-complex from the escherichia coli pyruvate dehydrogenase multi-4 enzyme complex
35d2r8oa1



not modelled 100.0 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
36d1ik6a1



not modelled 100.0 52
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
37d1r9ja1



not modelled 100.0 16
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
38d1itza2



not modelled 100.0 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
39d1gpua2



not modelled 100.0 16
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
40c3ahhA_



not modelled 100.0 11
PDB header:lyase
Chain: A: PDB Molecule:xylulose 5-phosphate/fructose 6-phosphate phosphoketolase;
PDBTitle: h142a mutant of phosphoketolase from bifidobacterium breve complexed2 with acetyl thiamine diphosphate
41d2bfdb2



not modelled 100.0 36
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
42d1umdb2



not modelled 100.0 39
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
43d1qs0b2



not modelled 100.0 47
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
44d2ozlb2



not modelled 100.0 35
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
45d1w85b2



not modelled 100.0 40
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
46d2ieaa1



not modelled 100.0 10
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
47d1ik6a2



not modelled 100.0 45
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
48c4wbxC_



not modelled 99.9 16
PDB header:oxidoreductase
Chain: C: PDB Molecule:2-keto acid:ferredoxin oxidoreductase subunit alpha;
PDBTitle: conserved hypothetical protein pf1771 from pyrococcus furiosus solved2 by sulfur sad using swiss light source data
49c5c4iA_



not modelled 99.8 16
PDB header:oxidoreductase
Chain: A: PDB Molecule:oxalate oxidoreductase subunit alpha;
PDBTitle: structure of an oxalate oxidoreductase
50c5b47A_



not modelled 99.8 15
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-oxoacid--ferredoxin oxidoreductase alpha subunit;
PDBTitle: 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai -2 pyruvate complex
51d2r8oa3



not modelled 99.8 13
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
52d1itza3



not modelled 99.8 12
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
53d1r9ja3



not modelled 99.8 15
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
54c6n2nA_



not modelled 99.7 14
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate flavodoxin/ferredoxin oxidoreductase domain
PDBTitle: crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from2 magnetococcus marinus
55d1gpua3



not modelled 99.7 12
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
56c2c3yA_



not modelled 99.7 15
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate-ferredoxin oxidoreductase;
PDBTitle: crystal structure of the radical form of2 pyruvate:ferredoxin oxidoreductase from desulfovibrio3 africanus
57c5b48A_



not modelled 99.7 18
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-oxoacid--ferredoxin oxidoreductase alpha subunit;
PDBTitle: 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai
58c6cipD_



not modelled 99.6 13
PDB header:oxidoreductase
Chain: D: PDB Molecule:pyruvate-ferredoxin oxidoreductase;
PDBTitle: pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with2 acetyl-tpp bound
59c3ju3A_



not modelled 99.6 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 2-oxoacid ferredoxin oxidoreductase, alpha chain;
PDBTitle: crystal structure of alpha chain of probable 2-oxoacid ferredoxin2 oxidoreductase from thermoplasma acidophilum
60d2ieaa3



not modelled 99.6 11
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
61d2c42a3



not modelled 99.2 13
Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Pyruvate-ferredoxin oxidoreductase, PFOR, domain II
62c1powA_



not modelled 98.1 13
PDB header:oxidoreductase(oxygen as acceptor)
Chain: A: PDB Molecule:pyruvate oxidase;
PDBTitle: the refined structures of a stabilized mutant and of wild-type2 pyruvate oxidase from lactobacillus plantarum
63c3ey9B_



not modelled 98.1 15
PDB header:oxidoreductase
Chain: B: PDB Molecule:pyruvate dehydrogenase [cytochrome];
PDBTitle: structural basis for membrane binding and catalytic activation of the2 peripheral membrane enzyme pyruvate oxidase from escherichia coli
64c1t9dB_



not modelled 98.0 16
PDB header:transferase
Chain: B: PDB Molecule:acetolactate synthase, mitochondrial;
PDBTitle: crystal structure of yeast acetohydroxyacid synthase in complex with a2 sulfonylurea herbicide, metsulfuron methyl
65c3eyaE_



not modelled 98.0 13
PDB header:oxidoreductase
Chain: E: PDB Molecule:pyruvate dehydrogenase [cytochrome];
PDBTitle: structural basis for membrane binding and catalytic2 activation of the peripheral membrane enzyme pyruvate3 oxidase from escherichia coli
66c1yi1A_



not modelled 98.0 14
PDB header:transferase
Chain: A: PDB Molecule:acetolactate synthase;
PDBTitle: crystal structure of arabidopsis thaliana acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, tribenuron methyl
67d2c42a1



not modelled 97.9 15
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:PFOR Pyr module
68d1pvda2



not modelled 97.9 10
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
69c2x7jA_



not modelled 97.8 13
PDB header:transferase
Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene
PDBTitle: structure of the menaquinone biosynthesis protein mend from2 bacillus subtilis
70c2djiA_



not modelled 97.8 12
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate oxidase;
PDBTitle: crystal structure of pyruvate oxidase from aerococcus2 viridans containing fad
71c2q27B_



not modelled 97.8 11
PDB header:lyase
Chain: B: PDB Molecule:oxalyl-coa decarboxylase;
PDBTitle: crystal structure of oxalyl-coa decarboxylase from escherichia coli
72c5ahkB_



not modelled 97.8 11
PDB header:transferase
Chain: B: PDB Molecule:acetolactate synthase ii, large subunit;
PDBTitle: crystal structure of acetohydroxy acid synthase pf5 from2 pseudomonas protegens
73c2nxwB_



not modelled 97.8 16
PDB header:lyase
Chain: B: PDB Molecule:phenyl-3-pyruvate decarboxylase;
PDBTitle: crystal structure of phenylpyruvate decarboxylase of azospirillum2 brasilense
74c2ji6B_



not modelled 97.8 13
PDB header:lyase
Chain: B: PDB Molecule:oxalyl-coa decarboxylase;
PDBTitle: x-ray structure of oxalyl-coa decarboxylase in complex with 3-deaza-2 thdp and oxalyl-coa
75c2ag1A_



not modelled 97.8 16
PDB header:lyase
Chain: A: PDB Molecule:benzaldehyde lyase;
PDBTitle: crystal structure of benzaldehyde lyase (bal)- semet
76c2vbgB_



not modelled 97.7 12
PDB header:lyase
Chain: B: PDB Molecule:branched-chain alpha-ketoacid decarboxylase;
PDBTitle: the complex structure of the branched-chain keto acid2 decarboxylase (kdca) from lactococcus lactis with 2r-1-3 hydroxyethyl-deazathdp
77c1upaC_



not modelled 97.7 15
PDB header:synthase
Chain: C: PDB Molecule:carboxyethylarginine synthase;
PDBTitle: carboxyethylarginine synthase from streptomyces2 clavuligerus (semet structure)
78d1zpda2



not modelled 97.7 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
79c2vbiF_



not modelled 97.7 13
PDB header:lyase
Chain: F: PDB Molecule:pyruvate decarboxylase;
PDBTitle: holostructure of pyruvate decarboxylase from acetobacter pasteurianus
80c2v3wC_



not modelled 97.7 13
PDB header:lyase
Chain: C: PDB Molecule:benzoylformate decarboxylase;
PDBTitle: crystal structure of the benzoylformate decarboxylase variant l461a2 from pseudomonas putida
81c2pgnA_



not modelled 97.6 12
PDB header:hydrolase
Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh);
PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione
82d2djia2



not modelled 97.6 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
83d2ez9a2



not modelled 97.6 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
84c2panF_



not modelled 97.6 13
PDB header:lyase
Chain: F: PDB Molecule:glyoxylate carboligase;
PDBTitle: crystal structure of e. coli glyoxylate carboligase
85c1jscA_



not modelled 97.5 13
PDB header:lyase
Chain: A: PDB Molecule:acetohydroxy-acid synthase;
PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors
86d1q6za2



not modelled 97.4 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
87d1t9ba2



not modelled 97.4 16
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
88c4k9qB_



not modelled 97.4 14
PDB header:lyase
Chain: B: PDB Molecule:benzoylformate decarboxylase;
PDBTitle: the crystal structure of benzoylformate decarboxylase from2 polynucleobacter necessarius
89c4rjjB_



not modelled 97.3 14
PDB header:lyase
Chain: B: PDB Molecule:acetolactate synthase;
PDBTitle: acetolactate synthase from bacillus subtilis bound to thdp - crystal2 form ii
90d2ji7a3



not modelled 97.3 19
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
91d1ybha2



not modelled 97.3 15
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
92c2w93A_



not modelled 97.3 9
PDB header:lyase
Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1;
PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate pyruvamide
93d1jsca3



not modelled 97.2 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
94d1ovma2



not modelled 97.2 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
95c3lq1A_



not modelled 96.9 11
PDB header:transferase
Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
PDBTitle: crystal structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-2 carboxylic acid synthase/2-oxoglutarate decarboxylase from listeria3 monocytogenes str. 4b f2365
96d1t9ba3



not modelled 96.9 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
97c1ozhD_



not modelled 96.7 12
PDB header:lyase
Chain: D: PDB Molecule:acetolactate synthase, catabolic;
PDBTitle: the crystal structure of klebsiella pneumoniae acetolactate2 synthase with enzyme-bound cofactor and with an unusual3 intermediate.
98c1yd7A_



not modelled 96.5 19
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-keto acid:ferredoxin oxidoreductase subunit alpha;
PDBTitle: conserved hypothetical protein pfu-1647980-001 from pyrococcus2 furiosus
99c2jlaD_



not modelled 96.5 11
PDB header:transferase
Chain: D: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene
PDBTitle: crystal structure of e.coli mend, 2-succinyl-5-enolpyruvyl-2 6-hydroxy-3-cyclohexadiene-1-carboxylate synthase - semet3 protein
100c4q9dA_



not modelled 96.5 15
PDB header:lyase
Chain: A: PDB Molecule:benzoylformate decarboxylase;
PDBTitle: x-ray structure of a putative thiamin diphosphate-dependent enzyme2 isolated from mycobacterium smegmatis
101c1zpdA_



not modelled 96.4 14
PDB header:alcohol fermentation
Chain: A: PDB Molecule:pyruvate decarboxylase;
PDBTitle: pyruvate decarboxylase from zymomonas mobilis
102d1ozha3



not modelled 96.2 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
103d2ji7a2



not modelled 96.1 12
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
104d1ozha2



not modelled 96.1 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
105d2ihta2



not modelled 95.9 15
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
106c5b46B_



not modelled 95.4 18
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoacid--ferredoxin oxidoreductase beta subunit;
PDBTitle: 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand2 free form
107d1ybha3



not modelled 95.0 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
108c5essB_



not modelled 94.6 19
PDB header:transferase
Chain: B: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
PDBTitle: crystal structure of m. tuberculosis mend bound to mg2+ and covalent2 intermediate i (a thdp and decarboxylated 2-oxoglutarate adduct)
109c1ovmC_



not modelled 93.8 14
PDB header:lyase
Chain: C: PDB Molecule:indole-3-pyruvate decarboxylase;
PDBTitle: crystal structure of indolepyruvate decarboxylase from2 enterobacter cloacae
110d1q6za3



not modelled 92.7 12
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
111d2ez9a3



not modelled 85.0 15
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
112d2djia3



not modelled 83.8 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
113c6n2oB_



not modelled 82.4 11
PDB header:oxidoreductase
Chain: B: PDB Molecule:pyruvate ferredoxin/flavodoxin oxidoreductase, beta
PDBTitle: 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus2 with 2-oxoglutarate, coenzyme a and succinyl-coa bound
114d1uxya1



not modelled 81.9 12
Fold:FAD-binding/transporter-associated domain-like
Superfamily:FAD-binding/transporter-associated domain-like
Family:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
115d2ozla1



not modelled 75.5 18
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase PP module
116d1vmea1



not modelled 75.2 14
Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
117d1zpda3



not modelled 73.6 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
118d2ihta3



not modelled 73.4 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
119d1ovma3



not modelled 71.7 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
120c2eguA_



not modelled 69.8 15
PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of o-acetylserine sulfhydrase from geobacillus2 kaustophilus hta426

Binding site prediction 

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below