1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	I	V	G	V	G	I	D	L	V	S	I	P	D	F	A	E	Q	V	D	Q	P	G	T	V	F	A	E	T	F	T	P	G	E	R	R	D	A	S	D	K	S	S	S	A	A	R	H	L	A	A	R	W	A	A	K	E	A	V
Secondary structure
SS confidence
Disorder		?	?																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	K	A	W	S	G	S	R	F	A	Q	R	P	V	L	P	E	D	I	H	R	D	I	E	V	V	T	D	M	W	G	R	P	R	V	R	L	T	G	A	I	A	E	Y	L	A	D	V	T	I	H	V	S	L	T	H	E	G	D	T
Secondary structure
SS confidence
Disorder							?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130
Sequence		A	A	A	V	A	I	L	E	A	P
Secondary structure
SS confidence
Disorder										?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 40%) Beta strand ( 29%)

Rank Aligned region

PDB 5vbx chain B Region: 2 - 129 Aligned: 122 Modelled: 128 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: B: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: crystal structure of holo-[acyl-carrier-protein] synthase (acps) from2 escherichia coli Phyre2 PDB 5cmo chain B Region: 3 - 128 Aligned: 120 Modelled: 120 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: B: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: crystal structure of holo-[acyl-carrier-protein] synthase (acps) from2 neisseria meningitidis Phyre2 PDB 3hqj chain A Region: 3 - 130 Aligned: 112 Modelled: 128 Confidence: 100.0% Identity: 95% PDB header:transferase Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: structure-function analysis of mycobacterium tuberculosis2 acyl carrier protein synthase (acps). Phyre2 PDB 2jbz chain A Region: 1 - 129 Aligned: 120 Modelled: 129 Confidence: 100.0% Identity: 37% PDB header:transferase Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: crystal structure of the streptomyces coelicolor holo-2 [acyl-carrier-protein] synthase (acps) in complex with3 coenzyme a at 1.6 a Phyre2 PDB 3h88 chain A Region: 3 - 128 Aligned: 120 Modelled: 120 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: crystal structure of 4'-phosphopantetheinyl transferase acps from2 vibrio cholerae o1 biovar eltor Phyre2 PDB 2qg8 chain A Region: 3 - 127 Aligned: 117 Modelled: 125 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:acyl carrier protein synthase py06285; PDBTitle: plasmodium yoelii acyl carrier protein synthase py06285 with adp bound Phyre2 PDB 3ne9 chain B Region: 2 - 128 Aligned: 127 Modelled: 124 Confidence: 100.0% Identity: 46% PDB header:transferase Chain: B: PDB Molecule:phosphopantetheine protein transferase, ppt1p; PDBTitle: chronobacterium ammoiniagenes apo-acps strucutre Phyre2 PDB 1fth chain A Region: 3 - 128 Aligned: 113 Modelled: 126 Confidence: 100.0% Identity: 27% Fold: 4'-phosphopantetheinyl transferase Superfamily: 4'-phosphopantetheinyl transferase Family: Holo-(acyl carrier protein) synthase ACPS Phyre2 PDB 1f7l chain A Region: 3 - 128 Aligned: 115 Modelled: 126 Confidence: 100.0% Identity: 30% Fold: 4'-phosphopantetheinyl transferase Superfamily: 4'-phosphopantetheinyl transferase Family: Holo-(acyl carrier protein) synthase ACPS Phyre2 PDB 5xuk chain A Region: 6 - 127 Aligned: 113 Modelled: 122 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: crystal structure of helicobacter pylori holo-[acyl-carrier-protein]2 synthase (acps) in complex with coenzyme a Phyre2 PDB 5xum chain A Region: 3 - 128 Aligned: 107 Modelled: 125 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: crystal structure of thermotoga maritima holo-[acyl-carrier-protein]2 synthase (acps) Phyre2 PDB 2was chain A Region: 5 - 128 Aligned: 108 Modelled: 112 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase; PDBTitle: structure of the fungal type i fas ppt domain Phyre2 PDB 3f09 chain B Region: 1 - 128 Aligned: 106 Modelled: 116 Confidence: 100.0% Identity: 30% PDB header:transferase Chain: B: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: 1.82 angstrom resolution crystal structure of holo-(acyl-carrier-2 protein) synthase (acps) from staphylococcus aureus Phyre2 PDB 3hyk chain B Region: 2 - 129 Aligned: 111 Modelled: 127 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: B: PDB Molecule:holo-[acyl-carrier-protein] synthase; PDBTitle: 2.31 angstrom resolution crystal structure of a holo-(acyl-carrier-2 protein) synthase from bacillus anthracis str. ames in complex with3 coa (3',5'-adp) Phyre2 PDB 3hmj chain B Region: 5 - 128 Aligned: 115 Modelled: 124 Confidence: 99.4% Identity: 29% PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: saccharomyces cerevisiae fas type i Phyre2 PDB 1qr0 chain A domain 2 Region: 6 - 130 Aligned: 105 Modelled: 117 Confidence: 99.1% Identity: 14% Fold: 4'-phosphopantetheinyl transferase Superfamily: 4'-phosphopantetheinyl transferase Family: 4'-Phosphopantetheinyl transferase SFP Phyre2 PDB 1qr0 chain A Region: 6 - 126 Aligned: 101 Modelled: 113 Confidence: 98.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:4'-phosphopantetheinyl transferase sfp; PDBTitle: crystal structure of the 4'-phosphopantetheinyl transferase sfp-2 coenzyme a complex Phyre2 PDB 1qr0 chain A domain 1 Region: 25 - 125 Aligned: 80 Modelled: 89 Confidence: 98.6% Identity: 20% Fold: 4'-phosphopantetheinyl transferase Superfamily: 4'-phosphopantetheinyl transferase Family: 4'-Phosphopantetheinyl transferase SFP Phyre2 PDB 2cg5 chain A Region: 25 - 130 Aligned: 90 Modelled: 106 Confidence: 98.6% Identity: 21% PDB header:transferase/hydrolase Chain: A: PDB Molecule:l-aminoadipate-semialdehyde dehydrogenase- PDBTitle: structure of aminoadipate-semialdehyde dehydrogenase-2 phosphopantetheinyl transferase in complex with cytosolic acyl3 carrier protein and coenzyme a Phyre2 PDB 4qvh chain A Region: 2 - 127 Aligned: 114 Modelled: 126 Confidence: 98.2% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:maltose-binding periplasmic protein, 4'-phosphopantetheinyl PDBTitle: crystal structure of the essential mycobacterium tuberculosis2 phosphopantetheinyl transferase pptt, solved as a fusion protein with3 maltose binding protein Phyre2 1 c5vbxB_ 2 c5cmoB_ 3 c3hqjA_ 4 c2jbzA_ 5 c3h88A_ 6 c2qg8A_ 7 c3ne9B_ 8 d1ftha_ 9 d1f7la_ 10 c5xukA_ 11 c5xumA_ 12 c2wasA_ 13 c3f09B_ 14 c3hykB_ 15 c3hmjB_ 16 d1qr0a2 17 c1qr0A_ 18 d1qr0a1 19 c2cg5A_ 20 c4qvhA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37