1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	I	P	D	A	Q	T	L	M	R	P	I	L	A	Y	L	A	D	G	Q	A	K	S	A	K	D	V	I	A	A	M	S	D	E	F	G	L	S	D	D	E	R	A	Q	M	L	P	S	G	R	Q	R	T	M	Y	D	R	V	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?														?	?	?	?	?	?																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	S	L	T	H	M	S	Q	A	G	L	L	D	R	P	T	R	G	H	V	Q	V	T	D	T	G	R	Q	V	L	K	A	H	P	E	R	V	D	M	A	V	L	R	E	F	P	S	Y	I	A	F	R	E	R	T	K	A	K	Q	P
Secondary structure
SS confidence
Disorder																			?							?	?	?																										?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	D	A	T	A	K	R	P	S	G	D	D	V	Q	V	S	P	E	D	L	I	D	A	A	L	A	E	N	R	A	A	V	E	G	E	I	L	K	K	A	L	T	L	S	P	T	G	F	E	D	L	V	I	R	L	L	E	A	M	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	G	R	A	G	A	V	E	R	T	S	A	S	G	D	A	G	I	D	G	I	I	S	Q	D	P	L	G	L	D	R	I	Y	V	Q	A	K	R	Y	A	V	D	Q	T	I	G	R	P	K	I	H	E	F	A	G	A	L	L	G	K
Secondary structure
SS confidence
Disorder														?																												?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Q	G	D	R	G	V	Y	I	T	T	S	S	F	S	R	G	A	R	E	E	A	E	R	I	N	A	R	I	E	L	I	D	G	A	R	L	A	E	L	L	V	R	Y	R	V	G	V	Q	A	V	Q	T	V	E	L	L	R	L	D	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.
Sequence		D	F	F	D	G	L
Secondary structure
SS confidence
Disorder						?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 49%) Beta strand ( 14%)

Rank Aligned region

PDB 4oc8 chain A Region: 106 - 287 Aligned: 170 Modelled: 182 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease aspbhi; PDBTitle: dna modification-dependent restriction endonuclease aspbhi Phyre2 PDB 4f0q chain C Region: 106 - 306 Aligned: 189 Modelled: 201 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: C: PDB Molecule:restriction endonuclease; PDBTitle: mspji restriction endonuclease - p21 form Phyre2 PDB 4f0q chain A Region: 106 - 306 Aligned: 184 Modelled: 187 Confidence: 99.9% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease; PDBTitle: mspji restriction endonuclease - p21 form Phyre2 PDB 1y88 chain A domain 2 Region: 164 - 285 Aligned: 117 Modelled: 122 Confidence: 99.9% Identity: 20% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: MRR-like Phyre2 PDB 1y88 chain A Region: 164 - 286 Aligned: 118 Modelled: 123 Confidence: 99.9% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein af1548; PDBTitle: crystal structure of protein of unknown function af1548 Phyre2 PDB 4xqk chain B Region: 158 - 260 Aligned: 88 Modelled: 103 Confidence: 97.2% Identity: 26% PDB header:hydrolase/dna Chain: B: PDB Molecule:llabiii; PDBTitle: atp-dependent type isp restriction-modification enzyme llabiii bound2 to dna Phyre2 PDB 3b73 chain A Region: 26 - 91 Aligned: 63 Modelled: 66 Confidence: 96.7% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phih1 repressor-like protein; PDBTitle: crystal structure of the phih1 repressor-like protein from haloarcula2 marismortui Phyre2 PDB 1xmx chain A Region: 168 - 279 Aligned: 105 Modelled: 112 Confidence: 96.6% Identity: 17% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: Hypothetical protein VC1899 Phyre2 PDB 1ob8 chain A Region: 166 - 248 Aligned: 74 Modelled: 83 Confidence: 96.1% Identity: 11% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: Hjc-like Phyre2 PDB 1gef chain A Region: 166 - 248 Aligned: 74 Modelled: 83 Confidence: 95.9% Identity: 19% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: Hjc-like Phyre2 PDB 3fov chain A Region: 169 - 240 Aligned: 64 Modelled: 72 Confidence: 95.3% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0102 protein rpa0323; PDBTitle: crystal structure of protein rpa0323 of unknown function from2 rhodopseudomonas palustris Phyre2 PDB 1r7j chain A Region: 5 - 92 Aligned: 65 Modelled: 72 Confidence: 95.2% Identity: 15% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Archaeal DNA-binding protein Phyre2 PDB 1uhm chain A Region: 2 - 85 Aligned: 73 Modelled: 73 Confidence: 94.9% Identity: 15% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Linker histone H1/H5 Phyre2 PDB 2eo0 chain A Region: 168 - 248 Aligned: 72 Modelled: 78 Confidence: 94.8% Identity: 19% PDB header:dna binding protein Chain: A: PDB Molecule:hypothetical protein st1444; PDBTitle: crystal structure of holliday junction resolvase st1444 Phyre2 PDB 5dym chain A Region: 9 - 92 Aligned: 68 Modelled: 69 Confidence: 94.6% Identity: 16% PDB header:dna binding protein Chain: A: PDB Molecule:padr-family transcriptional regulator; PDBTitle: crystal structure of a padr family transcription regulator from2 hypervirulent clostridium difficile r20291 - cdpadr_0991 to 1.893 angstrom resolution Phyre2 PDB 4esf chain A Region: 9 - 92 Aligned: 69 Modelled: 70 Confidence: 94.5% Identity: 20% PDB header:transcription Chain: A: PDB Molecule:padr-like transcriptional regulator; PDBTitle: crystal structure of padr-like transcriptional regulator (bce3449)2 from bacillus cereus strain atcc 10987 Phyre2 PDB 5flm chain E Region: 170 - 285 Aligned: 113 Modelled: 116 Confidence: 94.3% Identity: 15% PDB header:transcription Chain: E: PDB Molecule:dna-directed rna polymerases i, ii, and iii subunit rpabc1; PDBTitle: structure of transcribing mammalian rna polymerase ii Phyre2 PDB 6jyi chain B Region: 13 - 92 Aligned: 67 Modelled: 68 Confidence: 94.2% Identity: 18% PDB header:transcription Chain: B: PDB Molecule:transcriptional repressor padr; PDBTitle: crystal structure of the padr-like transcriptional regulator bc17562 from bacillus cereus Phyre2 PDB 1f5t chain A Region: 4 - 92 Aligned: 69 Modelled: 69 Confidence: 94.2% Identity: 22% PDB header:transcription/dna Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: diphtheria tox repressor (c102d mutant) complexed with2 nickel and dtxr consensus binding sequence Phyre2 PDB 3f8f chain A Region: 8 - 92 Aligned: 72 Modelled: 73 Confidence: 94.1% Identity: 13% PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, padr-like family; PDBTitle: crystal structure of multidrug binding transcriptional regulator lmrr2 complexed with daunomycin Phyre2 1 c4oc8A_ 2 c4f0qC_ 3 c4f0qA_ 4 d1y88a2 5 c1y88A_ 6 c4xqkB_ 7 c3b73A_ 8 d1xmxa_ 9 d1ob8a_ 10 d1gefa_ 11 c3fovA_ 12 d1r7ja_ 13 d1uhma_ 14 c2eo0A_ 15 c5dymA_ 16 c4esfA_ 17 c5flmE_ 18 c6jyiB_ 19 c1f5tA_ 20 c3f8fA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222