1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	T	T	A	D	F	K	N	G	L	V	L	V	I	D	G	Q	L	W	T	I	T	E	F	Q	H	V	K	P	G	K	G	P	A	F	V	R	T	K	L	K	N	V	L	S	G	K	V	V	D	K	T	F	N	A	G	V	K	V
Secondary structure
SS confidence
Disorder		?	?	?				?																						?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	T	A	T	V	D	R	R	D	T	T	Y	L	Y	R	D	G	S	D	F	V	F	M	D	S	Q	D	Y	E	Q	H	P	L	P	E	A	L	V	G	D	A	A	R	F	L	L	E	G	M	P	V	Q	V	A	F	H	N	G	V	P
Secondary structure
SS confidence
Disorder																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	Y	I	E	L	P	V	T	V	E	L	E	V	T	H	T	E	P	G	L	Q	G	D	R	S	S	A	G	T	K	P	A	T	L	Q	T	G	A	Q	I	N	V	P	L	F	I	N	T	G	D	K	L	K	V	D	S	R	D	G	S
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		Y	L	G	R	V	N	A
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 6%) Beta strand ( 56%)

Rank Aligned region

PDB 3oyy chain A Region: 1 - 185 Aligned: 182 Modelled: 185 Confidence: 100.0% Identity: 34% PDB header:translation Chain: A: PDB Molecule:elongation factor p; PDBTitle: structure of pseudomonas aeruginosa elongation factor p Phyre2 PDB 1ueb chain B Region: 1 - 185 Aligned: 178 Modelled: 185 Confidence: 100.0% Identity: 44% PDB header:rna binding protein Chain: B: PDB Molecule:elongation factor p; PDBTitle: crystal structure of translation elongation factor p from2 thermus thermophilus hb8 Phyre2 PDB 5j3b chain B Region: 3 - 185 Aligned: 175 Modelled: 183 Confidence: 100.0% Identity: 43% PDB header:translation Chain: B: PDB Molecule:elongation factor p; PDBTitle: structure of translation elongation factor p from acinetobacter2 baumannii Phyre2 PDB 1yby chain B Region: 2 - 185 Aligned: 177 Modelled: 184 Confidence: 100.0% Identity: 51% PDB header:translation Chain: B: PDB Molecule:translation elongation factor p; PDBTitle: conserved hypothetical protein cth-95 from clostridium thermocellum Phyre2 PDB 3a5z chain D Region: 2 - 185 Aligned: 174 Modelled: 184 Confidence: 100.0% Identity: 43% PDB header:ligase Chain: D: PDB Molecule:elongation factor p; PDBTitle: crystal structure of escherichia coli genx in complex with elongation2 factor p Phyre2 PDB 3tre chain A Region: 2 - 129 Aligned: 128 Modelled: 128 Confidence: 100.0% Identity: 38% PDB header:translation Chain: A: PDB Molecule:elongation factor p; PDBTitle: structure of a translation elongation factor p (efp) from coxiella2 burnetii Phyre2 PDB 1iz6 chain B Region: 2 - 126 Aligned: 125 Modelled: 125 Confidence: 100.0% Identity: 22% PDB header:biosynthetic protein Chain: B: PDB Molecule:initiation factor 5a; PDBTitle: crystal structure of translation initiation factor 5a from pyrococcus2 horikoshii Phyre2 PDB 1bkb chain A Region: 1 - 125 Aligned: 125 Modelled: 125 Confidence: 100.0% Identity: 23% PDB header:translation Chain: A: PDB Molecule:translation initiation factor 5a; PDBTitle: initiation factor 5a from archebacterium pyrobaculum2 aerophilum Phyre2 PDB 2eif chain A Region: 2 - 125 Aligned: 121 Modelled: 124 Confidence: 100.0% Identity: 26% PDB header:gene regulation Chain: A: PDB Molecule:protein (eukaryotic translation initiation factor 5a); PDBTitle: eukaryotic translation initiation factor 5a from methanococcus2 jannaschii Phyre2 PDB 3hks chain B Region: 2 - 124 Aligned: 123 Modelled: 123 Confidence: 100.0% Identity: 17% PDB header:translation, rna binding protein Chain: B: PDB Molecule:eukaryotic translation initiation factor 5a-2; PDBTitle: crystal structure of eukaryotic translation initiation2 factor eif-5a2 from arabidopsis thaliana Phyre2 PDB 3er0 chain A Region: 2 - 128 Aligned: 127 Modelled: 127 Confidence: 100.0% Identity: 20% PDB header:translation Chain: A: PDB Molecule:eukaryotic translation initiation factor 5a-2; PDBTitle: crystal structure of the full length eif5a from2 saccharomyces cerevisiae Phyre2 PDB 5hy6 chain A Region: 2 - 124 Aligned: 123 Modelled: 123 Confidence: 100.0% Identity: 16% PDB header:translation Chain: A: PDB Molecule:eukaryotic translation initiation factor 5a; PDBTitle: spodoptera frugiperda eukaryotic translation initiation factor eif5a Phyre2 PDB 1xtd chain A Region: 2 - 116 Aligned: 115 Modelled: 114 Confidence: 99.9% Identity: 21% PDB header:translation Chain: A: PDB Molecule:eukaryotic initiation factor 5a; PDBTitle: structural analysis of leishmania mexicana eukaryotic initiation2 factor 5a Phyre2 PDB 3cpf chain B Region: 2 - 125 Aligned: 114 Modelled: 124 Confidence: 99.9% Identity: 16% PDB header:cell cycle Chain: B: PDB Molecule:eukaryotic translation initiation factor 5a-1; PDBTitle: crystal structure of human eukaryotic translation initiation factor2 eif5a Phyre2 PDB 1ueb chain A domain 3 Region: 129 - 185 Aligned: 57 Modelled: 57 Confidence: 99.9% Identity: 56% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Cold shock DNA-binding domain-like Phyre2 PDB 1ueb chain A domain 1 Region: 1 - 63 Aligned: 63 Modelled: 63 Confidence: 99.9% Identity: 38% Fold: SH3-like barrel Superfamily: Translation proteins SH3-like domain Family: eIF5a N-terminal domain-like Phyre2 PDB 5wxk chain B Region: 1 - 63 Aligned: 63 Modelled: 63 Confidence: 99.9% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:elongation factor p; PDBTitle: earp bound with domain i of ef-p Phyre2 PDB 1ueb chain A domain 2 Region: 64 - 127 Aligned: 63 Modelled: 64 Confidence: 99.9% Identity: 38% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Cold shock DNA-binding domain-like Phyre2 PDB 3a5z chain F Region: 2 - 59 Aligned: 58 Modelled: 58 Confidence: 99.8% Identity: 40% PDB header:ligase Chain: F: PDB Molecule:elongation factor p; PDBTitle: crystal structure of escherichia coli genx in complex with elongation2 factor p Phyre2 PDB 1khi chain A Region: 2 - 125 Aligned: 119 Modelled: 124 Confidence: 99.3% Identity: 12% PDB header:structural protein Chain: A: PDB Molecule:hex1; PDBTitle: crystal structure of hex1 Phyre2 1 c3oyyA_ 2 c1uebB_ 3 c5j3bB_ 4 c1ybyB_ 5 c3a5zD_ 6 c3treA_ 7 c1iz6B_ 8 c1bkbA_ 9 c2eifA_ 10 c3hksB_ 11 c3er0A_ 12 c5hy6A_ 13 c1xtdA_ 14 c3cpfB_ 15 d1ueba3 16 d1ueba1 17 c5wxkB_ 18 d1ueba2 19 c3a5zF_ 20 c1khiA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99