1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	D	G	G	H	R	H	R	A	Q	P	V	S	V	R	P	N	R	H	R	R	T	R	V	S	R	A	Q	R	R	H	A	Q	Q	I	R	R	R	R	R	V	A	G	G	F	A	L	S	L	L	V	V	V	V	V	V	A	V	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	G	A	K	L	W	Q	T	M	L	G	F	G	N	D	Y	T	G	P	G	K	R	D	I	V	I	Q	I	R	A	G	D	S	T	T	A	V	G	E	T	L	L	K	H	G	V	V	A	T	V	R	A	F	V	D	A	A	H	G	N
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?	?	?	?	?													?																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	A	I	S	S	I	Q	P	G	F	Y	R	M	R	T	E	I	S	A	A	S	A	V	A	R	L	T	D	P	H	N	R	V	G	K	L	V	I	P	E	G	R	Q	L	D	D	T	T	D	M	K	T	N	V	V	N	P	G	I	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																															?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	L	I	S	R	A	T	C	V	D	L	D	G	T	Q	R	C	V	S	V	A	D	L	R	A	A	A	S	R	S	T	P	T	M	L	S	V	P	R	W	A	V	G	P	V	M	E	L	G	T	D	H	R	R	I	E	G	L	I	A
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?																							?						?	?	?	?	?				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	G	T	F	N	I	D	P	S	A	S	A	E	T	I	L	A	T	L	I	S	A	G	A	V	E	Y	M	K	S	G	L	V	D	T	A	K	S	L	G	L	S	P	Y	D	I	L	V	V	A	S	L	V	Q	Q	E	A	N	T	Q
Secondary structure
SS confidence
Disorder																															?				?				?	?	?																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	F	P	K	V	A	R	V	I	Y	N	R	L	H	E	H	R	T	L	E	F	D	S	T	V	N	Y	P	L	D	R	R	E	V	A	T	S	D	T	D	R	A	Q	R	T	P	W	N	T	Y	M	A	Q	G	L	P	A	T	A	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.
Sequence		C	S	P	G	V	D	A	L	R	A	A	E	H	P	V	P	G	D	W	L	Y	F	V	T	I	D	S	Q	G	T	T	L	F	T	R	D	Y	Q	Q	H	L	A	N	I	E	L	A	K	H	N	G	V	L	D	S	A	R
Secondary structure
SS confidence
Disorder																																																				?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 23%) Alpha helix ( 47%) Beta strand ( 8%) TM helix ( 5%) (View membrane topology prediction)

Rank Aligned region

PDB 4iiw chain B Region: 80 - 403 Aligned: 304 Modelled: 324 Confidence: 100.0% Identity: 23% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lmo1499 protein; PDBTitle: 2.6 angstrom crystal structure of putative yceg-like protein lmo14992 from listeria monocytogenes Phyre2 PDB 2r1f chain B Region: 125 - 417 Aligned: 256 Modelled: 271 Confidence: 100.0% Identity: 25% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:predicted aminodeoxychorismate lyase; PDBTitle: crystal structure of predicted aminodeoxychorismate lyase from2 escherichia coli Phyre2 PDB 4fet chain A Region: 279 - 395 Aligned: 101 Modelled: 101 Confidence: 96.9% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:spore cortex-lytic enzyme prepeptide; PDBTitle: catalytic domain of germination-specific lytic tansglycosylase sleb2 from bacillus anthracis Phyre2 PDB 4f55 chain A Region: 279 - 395 Aligned: 101 Modelled: 117 Confidence: 96.6% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:spore cortex-lytic enzyme; PDBTitle: crystal structure of the catalytic domain of the bacillus cereus sleb2 protein Phyre2 PDB 3bz6 chain A domain 1 Region: 276 - 304 Aligned: 29 Modelled: 29 Confidence: 51.4% Identity: 21% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: PSPTO2686-like Phyre2 PDB 2v3s chain B Region: 88 - 142 Aligned: 55 Modelled: 55 Confidence: 49.8% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structural insights into the recognition of substrates and2 activators by the osr1 kinase Phyre2 PDB 5mg3 chain F Region: 42 - 106 Aligned: 61 Modelled: 65 Confidence: 49.8% Identity: 16% PDB header:chaperone Chain: F: PDB Molecule:protein translocase subunit secf; PDBTitle: em fitted model of bacterial holo-translocon Phyre2 PDB 1dt9 chain A domain 3 Region: 64 - 103 Aligned: 40 Modelled: 40 Confidence: 47.1% Identity: 18% Fold: N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Superfamily: N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Family: N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Phyre2 PDB 1gjj chain A domain 2 Region: 354 - 360 Aligned: 7 Modelled: 7 Confidence: 40.5% Identity: 29% Fold: LEM/SAP HeH motif Superfamily: LEM domain Family: LEM domain Phyre2 PDB 1h9f chain A Region: 354 - 360 Aligned: 7 Modelled: 7 Confidence: 39.3% Identity: 29% Fold: LEM/SAP HeH motif Superfamily: LEM domain Family: LEM domain Phyre2 PDB 3bz6 chain A Region: 276 - 304 Aligned: 29 Modelled: 29 Confidence: 36.6% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0502 protein pspto_2686; PDBTitle: crystal structure of a conserved protein of unknown function from2 pseudomonas syringae pv. tomato str. dc3000 Phyre2 PDB 3e20 chain C Region: 63 - 103 Aligned: 41 Modelled: 41 Confidence: 33.8% Identity: 15% PDB header:translation Chain: C: PDB Molecule:eukaryotic peptide chain release factor subunit 1; PDBTitle: crystal structure of s.pombe erf1/erf3 complex Phyre2 PDB 5u8j chain A Region: 278 - 304 Aligned: 27 Modelled: 27 Confidence: 33.3% Identity: 19% PDB header:unknown function Chain: A: PDB Molecule:upf0502 protein bfj73_07745; PDBTitle: crystal structure of a protein of unknown function ecl_02571 involved2 in membrane biogenesis from enterobacter cloacae Phyre2 PDB 1jei chain A Region: 354 - 360 Aligned: 7 Modelled: 7 Confidence: 32.0% Identity: 14% Fold: LEM/SAP HeH motif Superfamily: LEM domain Family: LEM domain Phyre2 PDB 1ztw chain A domain 1 Region: 345 - 410 Aligned: 66 Modelled: 66 Confidence: 28.7% Identity: 12% Fold: DNA/RNA polymerases Superfamily: DNA/RNA polymerases Family: Reverse transcriptase Phyre2 PDB 1e0g chain A Region: 82 - 130 Aligned: 41 Modelled: 49 Confidence: 27.8% Identity: 27% Fold: LysM domain Superfamily: LysM domain Family: LysM domain Phyre2 PDB 1eg7 chain A Region: 304 - 327 Aligned: 24 Modelled: 24 Confidence: 27.7% Identity: 21% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 PDB 6btm chain A Region: 50 - 86 Aligned: 37 Modelled: 37 Confidence: 27.3% Identity: 16% PDB header:membrane protein Chain: A: PDB Molecule:alternative complex iii subunit a; PDBTitle: structure of alternative complex iii from flavobacterium johnsoniae2 (wild type) Phyre2 PDB 1gjj chain A Region: 354 - 360 Aligned: 7 Modelled: 7 Confidence: 25.5% Identity: 29% PDB header:membrane protein Chain: A: PDB Molecule:lap2; PDBTitle: n-terminal constant region of the nuclear envelope protein2 lap2 Phyre2 PDB 5fim chain A Region: 78 - 130 Aligned: 48 Modelled: 53 Confidence: 25.2% Identity: 17% PDB header:unknown function Chain: A: PDB Molecule:ygau; PDBTitle: the structure of kbp.k from e. coli Phyre2 1 c4iiwB_ 2 c2r1fB_ 3 c4fetA_ 4 c4f55A_ 5 d3bz6a1 6 c2v3sB_ 7 c5mg3F_ 8 d1dt9a3 9 d1gjja2 10 d1h9fa_ 11 c3bz6A_ 12 c3e20C_ 13 c5u8jA_ 14 d1jeia_ 15 d1ztwa1 16 d1e0ga_ 17 d1eg7a_ 18 c6btmA_ 19 c1gjjA_ 20 c5fimA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99