1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	Q	P	P	E	H	P	G	N	P	A	D	P	Q	G	G	N	Q	G	A	G	S	Y	P	P	P	G	Y	G	A	P	P	P	P	P	G	Y	G	P	P	P	G	T	Y	L	P	P	G	Y	N	A	P	P	P	P	P	G	Y	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	P	P	G	P	P	P	P	G	Y	P	T	H	L	Q	S	S	G	F	S	V	G	D	A	I	S	W	S	W	N	R	F	T	Q	N	A	V	T	L	V	V	P	V	L	A	Y	A	V	A	L	A	A	V	I	G	A	T	A	G	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	V	A	L	S	D	R	A	T	T	A	Y	T	N	T	S	G	V	S	S	E	S	V	D	I	T	M	T	P	A	A	G	I	V	M	F	L	G	Y	I	A	L	F	A	L	V	L	Y	M	H	A	G	I	L	T	G	C	L	D	I
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	D	G	K	P	V	T	I	A	T	F	F	R	P	R	N	L	G	L	V	L	V	T	G	L	L	I	V	A	V	T	F	I	G	G	L	L	C	V	I	P	G	L	I	F	G	F	V	A	Q	F	A	V	A	F	A	V	D	R	S
Secondary structure
SS confidence
Disorder			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	S	P	I	D	S	V	K	A	S	I	E	T	V	G	S	N	I	G	G	S	V	L	S	W	L	A	Q	L	T	A	V	L	V	G	E	L	L	C	F	V	G	M	L	I	G	I	P	V	A	A	L	I	H	V	Y	T	Y	R	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.
Sequence		L	S	G	G	Q	V	V	E	A	V	R	P	A	P	P	V	G	W	P	P	G	P	Q	L	A
Secondary structure
SS confidence
Disorder				?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 39%) Alpha helix ( 65%) Beta strand ( 0%) TM helix ( 38%) (View membrane topology prediction)

Rank Aligned region

PDB 4nl6 chain C Region: 2 - 82 Aligned: 81 Modelled: 81 Confidence: 95.3% Identity: 21% PDB header:splicing Chain: C: PDB Molecule:survival motor neuron protein; PDBTitle: structure of the full-length form of the protein smn found in healthy2 patients Phyre2 PDB 6d79 chain A Region: 83 - 300 Aligned: 200 Modelled: 203 Confidence: 56.4% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:sulfate transporter cysz; PDBTitle: structure of cysz, a sulfate permease from pseudomonas fragi Phyre2 PDB 4dji chain A Region: 93 - 325 Aligned: 232 Modelled: 233 Confidence: 46.7% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:probable glutamate/gamma-aminobutyrate antiporter; PDBTitle: structure of glutamate-gaba antiporter gadc Phyre2 PDB 2kpy chain A Region: 16 - 70 Aligned: 55 Modelled: 55 Confidence: 41.2% Identity: 25% PDB header:allergen Chain: A: PDB Molecule:major pollen allergen art v 1; PDBTitle: solution structure of the major allergen of artemisia vulgaris (art v2 1) Phyre2 PDB 6hwh chain B Region: 78 - 217 Aligned: 140 Modelled: 140 Confidence: 26.3% Identity: 16% PDB header:electron transport Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 5nda chain A Region: 254 - 281 Aligned: 28 Modelled: 28 Confidence: 13.4% Identity: 21% PDB header:protein Chain: A: PDB Molecule:rsp-c33leu -recombinant pulmonary surfactant-associated PDBTitle: nmr structural characterisation of pharmaceutically relevant proteins2 obtained through a novel recombinant production: the case of the3 pulmonary surfactant polypeptide c analogue rsp-c33leu. Phyre2 PDB 3ixz chain B Region: 254 - 287 Aligned: 34 Modelled: 34 Confidence: 13.3% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:potassium-transporting atpase subunit beta; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride Phyre2 PDB 3adm chain E Region: 47 - 72 Aligned: 26 Modelled: 26 Confidence: 12.9% Identity: 62% PDB header:structural protein Chain: E: PDB Molecule:collagen-like peptide; PDBTitle: crystal structure of (pro-pro-gly)4-hyp-ser-gly-(pro-pro-gly)4 Phyre2 PDB 3adm chain F Region: 47 - 72 Aligned: 26 Modelled: 26 Confidence: 12.9% Identity: 62% PDB header:structural protein Chain: F: PDB Molecule:collagen-like peptide; PDBTitle: crystal structure of (pro-pro-gly)4-hyp-ser-gly-(pro-pro-gly)4 Phyre2 PDB 3adm chain B Region: 47 - 72 Aligned: 26 Modelled: 26 Confidence: 12.9% Identity: 62% PDB header:structural protein Chain: B: PDB Molecule:collagen-like peptide; PDBTitle: crystal structure of (pro-pro-gly)4-hyp-ser-gly-(pro-pro-gly)4 Phyre2 PDB 3adm chain A Region: 47 - 72 Aligned: 26 Modelled: 26 Confidence: 12.9% Identity: 62% PDB header:structural protein Chain: A: PDB Molecule:collagen-like peptide; PDBTitle: crystal structure of (pro-pro-gly)4-hyp-ser-gly-(pro-pro-gly)4 Phyre2 PDB 5lj7 chain B Region: 83 - 249 Aligned: 140 Modelled: 141 Confidence: 12.3% Identity: 12% PDB header:transport protein Chain: B: PDB Molecule:macrolide export atp-binding/permease protein macb; PDBTitle: structure of aggregatibacter actinomycetemcomitans macb bound to atp2 (p21) Phyre2 PDB 3abn chain A Region: 47 - 72 Aligned: 26 Modelled: 26 Confidence: 10.9% Identity: 62% PDB header:structural protein Chain: A: PDB Molecule:collagen-like peptide; PDBTitle: crystal structure of (pro-pro-gly)4-hyp-asp-gly-(pro-pro-gly)4 at 1.022 a Phyre2 PDB 3adm chain C Region: 48 - 72 Aligned: 25 Modelled: 25 Confidence: 10.8% Identity: 60% PDB header:structural protein Chain: C: PDB Molecule:collagen-like peptide; PDBTitle: crystal structure of (pro-pro-gly)4-hyp-ser-gly-(pro-pro-gly)4 Phyre2 PDB 3j8e chain G Region: 212 - 279 Aligned: 68 Modelled: 68 Confidence: 10.5% Identity: 6% PDB header:transport protein/isomerase Chain: G: PDB Molecule:ryanodine receptor 1; PDBTitle: cryo-em structure of ryanodine receptor/calstabin-2 complex Phyre2 PDB 4tqv chain I Region: 86 - 267 Aligned: 171 Modelled: 182 Confidence: 10.4% Identity: 9% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2jln chain A Region: 93 - 314 Aligned: 222 Modelled: 222 Confidence: 10.3% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:mhp1; PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter Phyre2 PDB 5ws4 chain A Region: 83 - 248 Aligned: 140 Modelled: 149 Confidence: 10.0% Identity: 17% PDB header:membrane protein Chain: A: PDB Molecule:macrolide export atp-binding/permease protein macb; PDBTitle: crystal structure of tripartite-type abc transporter macb from2 acinetobacter baumannii Phyre2 PDB 3adm chain D Region: 47 - 71 Aligned: 25 Modelled: 25 Confidence: 9.9% Identity: 64% PDB header:structural protein Chain: D: PDB Molecule:collagen-like peptide; PDBTitle: crystal structure of (pro-pro-gly)4-hyp-ser-gly-(pro-pro-gly)4 Phyre2 PDB 2d3f chain E Region: 47 - 72 Aligned: 26 Modelled: 26 Confidence: 9.6% Identity: 62% PDB header:structural protein Chain: E: PDB Molecule:collagen model peptides (pro-pro-gly)4-pro-hyp- PDBTitle: crystal structures of collagen model peptides (pro-pro-gly)2 4-pro-hyp-gly-(pro-pro-gly)4 Phyre2 1 c4nl6C_ 2 c6d79A_ 3 c4djiA_ 4 c2kpyA_ 5 c6hwhb_ 6 c5ndaA_ 7 c3ixzB_ 8 c3admE_ 9 c3admF_ 10 c3admB_ 11 c3admA_ 12 c5lj7B_ 13 c3abnA_ 14 c3admC_ 15 c3j8eG_ 16 c4tqvI_ 17 c2jlnA_ 18 c5ws4A_ 19 c3admD_ 20 c2d3fE_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62