1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	I	Q	R	A	V	L	L	I	A	D	I	G	G	Y	T	N	Y	M	H	W	N	R	K	H	L	A	H	A	Q	W	T	V	A	Q	L	L	E	S	V	I	D	A	A	K	G	M	K	L	A	K	L	E	G	D	A	A	F	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.
Sequence		W	A	P	G	G	Q	H	Q	C	P	G	M	R	P	A	P	A	D	A	P	E	V	P	H	A	A	R	A	D	Q	K	R	P	S	L	R	L
Secondary structure
SS confidence
Disorder										?			?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 32%) Alpha helix ( 42%) Beta strand ( 19%)

Rank Aligned region

PDB 1fx2 chain A Region: 6 - 63 Aligned: 57 Modelled: 58 Confidence: 85.6% Identity: 21% Fold: Ferredoxin-like Superfamily: Nucleotide cyclase Family: Adenylyl and guanylyl cyclase catalytic domain Phyre2 PDB 1fx4 chain A Region: 6 - 60 Aligned: 54 Modelled: 55 Confidence: 53.7% Identity: 22% Fold: Ferredoxin-like Superfamily: Nucleotide cyclase Family: Adenylyl and guanylyl cyclase catalytic domain Phyre2 PDB 4cll chain A Region: 6 - 63 Aligned: 57 Modelled: 58 Confidence: 33.8% Identity: 23% PDB header:lyase Chain: A: PDB Molecule:adenylate cyclase type 10; PDBTitle: crystal structure of human soluble adenylyl cyclase in complex with2 bicarbonate Phyre2 PDB 4wrp chain B Region: 21 - 37 Aligned: 17 Modelled: 17 Confidence: 27.3% Identity: 35% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: the c-terminal domain of gene product lpg0944 from legionella2 pneumophila subsp. pneumophila str. philadelphia 1 Phyre2 PDB 1cjk chain A Region: 4 - 64 Aligned: 60 Modelled: 61 Confidence: 26.1% Identity: 17% PDB header:lyase/lyase/signaling protein Chain: A: PDB Molecule:adenylate cyclase, type v; PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn Phyre2 PDB 1azs chain A Region: 4 - 66 Aligned: 62 Modelled: 63 Confidence: 25.4% Identity: 16% Fold: Ferredoxin-like Superfamily: Nucleotide cyclase Family: Adenylyl and guanylyl cyclase catalytic domain Phyre2 PDB 2mzv chain A Region: 67 - 87 Aligned: 21 Modelled: 21 Confidence: 19.2% Identity: 43% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:cystatin; PDBTitle: resonance assignments and secondary structure of a phytocystatin from2 sesamum indicum Phyre2 PDB 1t64 chain A Region: 32 - 71 Aligned: 38 Modelled: 40 Confidence: 17.4% Identity: 24% Fold: Arginase/deacetylase Superfamily: Arginase/deacetylase Family: Histone deacetylase, HDAC Phyre2 PDB 4z5q chain A Region: 64 - 73 Aligned: 10 Modelled: 10 Confidence: 16.8% Identity: 40% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome p450 hydroxylase; PDBTitle: crystal structure of the lnmz cytochrome p450 hydroxylase from the2 leinamycin biosynthetic pathway of streptomyces atroolivaceus s-1403 at 1.8 a resolution Phyre2 PDB 5aj3 chain C Region: 65 - 76 Aligned: 12 Modelled: 12 Confidence: 16.1% Identity: 58% PDB header:ribosome Chain: C: PDB Molecule:mitoribosomal protein us3m, mrps24; PDBTitle: structure of the small subunit of the mammalian mitoribosome Phyre2 PDB 2d11 chain H Region: 20 - 25 Aligned: 6 Modelled: 6 Confidence: 13.7% Identity: 83% PDB header:cell adhesion Chain: H: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf2; PDBTitle: crystal structure of the radixin ferm domain complexed with2 the nherf-2 c-terminal tail peptide Phyre2 PDB 2d11 chain G Region: 20 - 25 Aligned: 6 Modelled: 6 Confidence: 13.7% Identity: 83% PDB header:cell adhesion Chain: G: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf2; PDBTitle: crystal structure of the radixin ferm domain complexed with2 the nherf-2 c-terminal tail peptide Phyre2 PDB 2d11 chain E Region: 20 - 25 Aligned: 6 Modelled: 6 Confidence: 13.5% Identity: 83% PDB header:cell adhesion Chain: E: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf2; PDBTitle: crystal structure of the radixin ferm domain complexed with2 the nherf-2 c-terminal tail peptide Phyre2 PDB 2d11 chain F Region: 20 - 25 Aligned: 6 Modelled: 6 Confidence: 13.5% Identity: 83% PDB header:cell adhesion Chain: F: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf2; PDBTitle: crystal structure of the radixin ferm domain complexed with2 the nherf-2 c-terminal tail peptide Phyre2 PDB 5j1h chain B Region: 22 - 53 Aligned: 32 Modelled: 32 Confidence: 12.8% Identity: 19% PDB header:structural protein Chain: B: PDB Molecule:plectin,plectin; PDBTitle: structure of the spectrin repeats 5 and 6 of the plakin domain of2 plectin Phyre2 PDB 5y1i chain A Region: 64 - 72 Aligned: 9 Modelled: 9 Confidence: 12.6% Identity: 56% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome p450; PDBTitle: the crystal structure of gfsf Phyre2 PDB 3dan chain A Region: 64 - 73 Aligned: 10 Modelled: 10 Confidence: 11.8% Identity: 30% PDB header:lyase Chain: A: PDB Molecule:cytochrome p450 74a2; PDBTitle: crystal structure of allene oxide synthase Phyre2 PDB 3ivy chain A Region: 60 - 72 Aligned: 13 Modelled: 13 Confidence: 11.7% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome p450 cyp125; PDBTitle: crystal structure of mycobacterium tuberculosis cytochrome p4502 cyp125, p212121 crystal form Phyre2 PDB 4r21 chain B Region: 53 - 73 Aligned: 21 Modelled: 21 Confidence: 11.6% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:cytochrome p450 family 17 polypeptide 2; PDBTitle: zebra fish cytochrome p450 17a2 with progesterone Phyre2 PDB 3cwz chain B Region: 27 - 57 Aligned: 31 Modelled: 31 Confidence: 11.0% Identity: 29% PDB header:transport protein Chain: B: PDB Molecule:rab6-interacting protein 1; PDBTitle: structure of rab6(gtp)-r6ip1 complex Phyre2 1 d1fx2a_ 2 d1fx4a_ 3 c4cllA_ 4 c4wrpB_ 5 c1cjkA_ 6 d1azsa_ 7 c2mzvA_ 8 d1t64a_ 9 c4z5qA_ 10 c5aj3c_ 11 c2d11H_ 12 c2d11G_ 13 c2d11E_ 14 c2d11F_ 15 c5j1hB_ 16 c5y1iA_ 17 c3danA_ 18 c3ivyA_ 19 c4r21B_ 20 c3cwzB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99