1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	S	I	S	L	T	S	L	A	A	E	K	L	A	E	A	Q	Q	T	H	S	G	R	A	A	H	T	I	H	G	G	H	T	H	E	L	R	Q	T	V	L	A	L	L	A	G	H	D	L	S	E	H	D	S	P	G	E	A	T
Secondary structure
SS confidence
Disorder		?	?													?	?	?	?	?	?	?	?	?	?																										?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.
Sequence		L	Q	V	L	Q	G	H	V	C	L	T	A	G	E	D	A	W	N	G	R	A	G	D	Y	V	A	I	P	P	T	R	H	A	L	H	A	V	E	D	S	V	I	M	L	T	V	L	K	S	L	P	D	A	H	S	G	S
Secondary structure
SS confidence
Disorder																																																	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 9%) Beta strand ( 50%)

Rank Aligned region

PDB 1yhf chain A domain 1 Region: 13 - 110 Aligned: 96 Modelled: 98 Confidence: 99.8% Identity: 27% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: TM1287-like Phyre2 PDB 5j4f chain B Region: 27 - 108 Aligned: 80 Modelled: 82 Confidence: 99.8% Identity: 24% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the n-terminally his6-tagged hp0902, an2 uncharacterized protein from helicobacter pylori 26695 Phyre2 PDB 3fjs chain C Region: 12 - 110 Aligned: 99 Modelled: 99 Confidence: 99.8% Identity: 19% PDB header:biosynthetic protein Chain: C: PDB Molecule:uncharacterized protein with rmlc-like cupin fold; PDBTitle: crystal structure of a putative biosynthetic protein with rmlc-like2 cupin fold (reut_b4087) from ralstonia eutropha jmp134 at 1.90 a3 resolution Phyre2 PDB 2ozj chain B Region: 12 - 108 Aligned: 95 Modelled: 97 Confidence: 99.8% Identity: 14% PDB header:unknown function Chain: B: PDB Molecule:cupin 2, conserved barrel; PDBTitle: crystal structure of a cupin superfamily protein (dsy2733) from2 desulfitobacterium hafniense dcb-2 at 1.60 a resolution Phyre2 PDB 3rns chain A Region: 13 - 108 Aligned: 94 Modelled: 96 Confidence: 99.8% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cupin 2 conserved barrel domain protein; PDBTitle: cupin 2 conserved barrel domain protein from leptotrichia buccalis Phyre2 PDB 2q30 chain C Region: 13 - 110 Aligned: 96 Modelled: 97 Confidence: 99.8% Identity: 21% PDB header:unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a rmlc-like cupin protein (dde_2303) from2 desulfovibrio desulfuricans subsp. at 1.94 a resolution Phyre2 PDB 1v70 chain A Region: 1 - 111 Aligned: 102 Modelled: 111 Confidence: 99.8% Identity: 24% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: TM1287-like Phyre2 PDB 2pfw chain B Region: 22 - 112 Aligned: 89 Modelled: 91 Confidence: 99.7% Identity: 20% PDB header:unknown function Chain: B: PDB Molecule:cupin 2, conserved barrel domain protein; PDBTitle: crystal structure of a rmlc-like cupin (sfri_3105) from shewanella2 frigidimarina ncimb 400 at 1.90 a resolution Phyre2 PDB 4e2g chain E Region: 23 - 110 Aligned: 85 Modelled: 88 Confidence: 99.7% Identity: 26% PDB header:structural genomics, unknown function Chain: E: PDB Molecule:cupin 2 conserved barrel domain protein; PDBTitle: crystal structure of cupin fold protein sthe2323 from sphaerobacter2 thermophilus Phyre2 PDB 2b8m chain A domain 1 Region: 21 - 110 Aligned: 88 Modelled: 90 Confidence: 99.7% Identity: 17% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: MJ0764-like Phyre2 PDB 3h8u chain A Region: 1 - 112 Aligned: 103 Modelled: 112 Confidence: 99.6% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized conserved protein with double-stranded PDBTitle: crystal structure of uncharacterized conserved protein with double-2 stranded beta-helix domain (yp_001338853.1) from klebsiella3 pneumoniae subsp. pneumoniae mgh 78578 at 1.80 a resolution Phyre2 PDB 3jzv chain A Region: 22 - 113 Aligned: 92 Modelled: 92 Confidence: 99.6% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein rru_a2000; PDBTitle: crystal structure of rru_a2000 from rhodospirillum rubrum: a cupin-22 domain. Phyre2 PDB 2oa2 chain A Region: 27 - 117 Aligned: 89 Modelled: 91 Confidence: 99.6% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bh2720 protein; PDBTitle: crystal structure of bh2720 (10175341) from bacillus halodurans at2 1.41 a resolution Phyre2 PDB 2gu9 chain B Region: 27 - 115 Aligned: 87 Modelled: 89 Confidence: 99.6% Identity: 14% PDB header:immune system Chain: B: PDB Molecule:tetracenomycin polyketide synthesis protein; PDBTitle: crystal structure of xc5357 from xanthomonas campestris: a2 putative tetracenomycin polyketide synthesis protein3 adopting a novel cupin subfamily structure Phyre2 PDB 5bxx chain A Region: 1 - 110 Aligned: 108 Modelled: 110 Confidence: 99.6% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:l-ectoine synthase; PDBTitle: crystal structure of the ectoine synthase from the cold-adapted marine2 bacterium sphingopyxis alaskensis Phyre2 PDB 5fpz chain A Region: 22 - 113 Aligned: 90 Modelled: 92 Confidence: 99.6% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:pectin degradation protein; PDBTitle: the structure of kdgf from yersinia enterocolitica with2 malonate bound in the active site. Phyre2 PDB 5fq0 chain A Region: 16 - 113 Aligned: 96 Modelled: 98 Confidence: 99.6% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:kdgf; PDBTitle: the structure of kdgf from halomonas sp. Phyre2 PDB 1vj2 chain A Region: 20 - 110 Aligned: 91 Modelled: 91 Confidence: 99.6% Identity: 18% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: TM1459-like Phyre2 PDB 5ono chain A Region: 1 - 111 Aligned: 107 Modelled: 111 Confidence: 99.6% Identity: 13% PDB header:metal binding protein Chain: A: PDB Molecule:l-ectoine synthase; PDBTitle: crystal structure of ectoine synthase from p. lautus Phyre2 PDB 3kgz chain A Region: 15 - 113 Aligned: 99 Modelled: 99 Confidence: 99.6% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cupin 2 conserved barrel domain protein; PDBTitle: crystal structure of a cupin 2 conserved barrel domain protein from2 rhodopseudomonas palustris Phyre2 1 d1yhfa1 2 c5j4fB_ 3 c3fjsC_ 4 c2ozjB_ 5 c3rnsA_ 6 c2q30C_ 7 d1v70a_ 8 c2pfwB_ 9 c4e2gE_ 10 d2b8ma1 11 c3h8uA_ 12 c3jzvA_ 13 c2oa2A_ 14 c2gu9B_ 15 c5bxxA_ 16 c5fpzA_ 17 c5fq0A_ 18 d1vj2a_ 19 c5onoA_ 20 c3kgzA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312