1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	H	R	D	D	H	I	N	P	P	R	P	R	G	L	D	V	P	C	A	R	L	R	A	T	N	P	L	R	A	L	A	R	C	V	Q	A	G	K	P	G	T	S	S	G	H	R	S	V	P	H	T	A	D	L	R	I	E	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?			?		?				?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	A	P	T	R	D	G	C	I	R	Q	A	V	L	G	T	V	E	S	F	L	D	L	E	S	A	H	A	V	H	T	R	L	R	R	L	T	A	D	R	D	D	D	L	L	V	A	V	L	E	E	V	I	Y	L	L	D	T	V	G
Secondary structure
SS confidence
Disorder																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.
Sequence		E	T	P	V	D	L	R	L	R	D	V	D	G	G	V	D	V	T	F	A	T	T	D	A	S	T	L	V	Q	V	G	A	V	P	K	A	V	S	L	N	E	L	R	F	S	Q	G	R	H	G	W	R	C	A	V	T	L	D	V
Secondary structure
SS confidence
Disorder																									?			?																				?											?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 25%) Beta strand ( 32%)

Rank Aligned region

PDB 5yzl chain A Region: 34 - 179 Aligned: 145 Modelled: 146 Confidence: 100.0% Identity: 16% PDB header:chaperone Chain: A: PDB Molecule:protein archease; PDBTitle: crystal structure of human archease d178a Phyre2 PDB 1jw3 chain A Region: 45 - 179 Aligned: 135 Modelled: 135 Confidence: 100.0% Identity: 19% Fold: MTH1598-like Superfamily: MTH1598-like Family: MTH1598-like Phyre2 PDB 4n2p chain C Region: 45 - 179 Aligned: 132 Modelled: 135 Confidence: 100.0% Identity: 16% PDB header:chaperone Chain: C: PDB Molecule:protein archease; PDBTitle: structure of archease from pyrococcus horikoshii Phyre2 PDB 1j5u chain A Region: 47 - 178 Aligned: 122 Modelled: 132 Confidence: 100.0% Identity: 16% Fold: MTH1598-like Superfamily: MTH1598-like Family: MTH1598-like Phyre2 PDB 3gku chain B Region: 58 - 179 Aligned: 119 Modelled: 122 Confidence: 88.0% Identity: 15% PDB header:rna binding protein Chain: B: PDB Molecule:probable rna-binding protein; PDBTitle: crystal structure of a probable rna-binding protein from clostridium2 symbiosum atcc 14940 Phyre2 PDB 2yzt chain A Region: 55 - 76 Aligned: 22 Modelled: 22 Confidence: 71.0% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative uncharacterized protein ttha1756; PDBTitle: crystal structure of uncharacterized conserved protein from thermus2 thermophilus hb8 Phyre2 PDB 6g1c chain V Region: 60 - 83 Aligned: 24 Modelled: 24 Confidence: 43.0% Identity: 25% PDB header:antitoxin Chain: V: PDB Molecule:antitoxin hicb; PDBTitle: crystal structure of the n-terminal domain of burkholderia2 pseudomallei antitoxin hicb Phyre2 PDB 5yrz chain C Region: 60 - 82 Aligned: 23 Modelled: 23 Confidence: 37.7% Identity: 4% PDB header:antitoxin/hydrolase Chain: C: PDB Molecule:hicb; PDBTitle: toxin-antitoxin complex from streptococcus pneumoniae Phyre2 PDB 6j7j chain A Region: 51 - 75 Aligned: 25 Modelled: 22 Confidence: 35.4% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:pseudomonas aeruginosa earp; PDBTitle: crystal structure of pseudomonas aeruginosa earp Phyre2 PDB 1f2r chain I Region: 34 - 76 Aligned: 43 Modelled: 43 Confidence: 31.9% Identity: 12% Fold: beta-Grasp (ubiquitin-like) Superfamily: CAD & PB1 domains Family: CAD domain Phyre2 PDB 4p7d chain A Region: 57 - 80 Aligned: 24 Modelled: 24 Confidence: 31.4% Identity: 8% PDB header:toxin Chain: A: PDB Molecule:antitoxin hicb3; PDBTitle: antitoxin hicb3 crystal structure Phyre2 PDB 5ubu chain C Region: 41 - 90 Aligned: 50 Modelled: 50 Confidence: 28.5% Identity: 6% PDB header:hydrolase Chain: C: PDB Molecule:putative acetamidase/formamidase; PDBTitle: 2.75 angstrom resolution crystal structure of acetamidase from2 yersinia enterocolitica. Phyre2 PDB 2f4l chain A domain 1 Region: 49 - 90 Aligned: 42 Modelled: 42 Confidence: 28.4% Identity: 12% Fold: CUB-like Superfamily: Acetamidase/Formamidase-like Family: Acetamidase/Formamidase-like Phyre2 PDB 1a9x chain A domain 5 Region: 58 - 76 Aligned: 19 Modelled: 19 Confidence: 26.9% Identity: 21% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: BC ATP-binding domain-like Phyre2 PDB 2wnm chain A Region: 53 - 88 Aligned: 36 Modelled: 36 Confidence: 26.8% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:gene 2; PDBTitle: solution structure of gp2 Phyre2 PDB 1w96 chain C domain 1 Region: 57 - 82 Aligned: 26 Modelled: 26 Confidence: 26.5% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Rudiment single hybrid motif Family: BC C-terminal domain-like Phyre2 PDB 6g1n chain B Region: 57 - 80 Aligned: 24 Modelled: 24 Confidence: 26.1% Identity: 21% PDB header:antitoxin Chain: B: PDB Molecule:antitoxin hicb; PDBTitle: crystal structure of the burkholderia pseudomallei antitoxin hicb Phyre2 PDB 1k0w chain A Region: 57 - 72 Aligned: 16 Modelled: 16 Confidence: 25.3% Identity: 19% Fold: AraD/HMP-PK domain-like Superfamily: AraD/HMP-PK domain-like Family: AraD-like aldolase/epimerase Phyre2 PDB 1ulz chain A domain 1 Region: 57 - 82 Aligned: 26 Modelled: 26 Confidence: 24.5% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Rudiment single hybrid motif Family: BC C-terminal domain-like Phyre2 PDB 2lmc chain A Region: 53 - 88 Aligned: 36 Modelled: 36 Confidence: 24.2% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:bacterial rna polymerase inhibitor; PDBTitle: structure of t7 transcription factor gp2-e. coli rnap jaw domain2 complex Phyre2 1 c5yzlA_ 2 d1jw3a_ 3 c4n2pC_ 4 d1j5ua_ 5 c3gkuB_ 6 c2yztA_ 7 c6g1cV_ 8 c5yrzC_ 9 c6j7jA_ 10 d1f2ri_ 11 c4p7dA_ 12 c5ubuC_ 13 d2f4la1 14 d1a9xa5 15 c2wnmA_ 16 d1w96c1 17 c6g1nB_ 18 d1k0wa_ 19 d1ulza1 20 c2lmcA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96