1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	A	Y	D	V	L	K	R	H	H	T	V	L	K	G	L	G	R	K	V	G	E	A	P	V	N	S	E	E	R	H	V	L	F	D	E	M	L	I	E	L	D	I	H	F	R	I	E	D	D	L	Y	Y	P	A	L	S	A	A
Secondary structure
SS confidence
Disorder		?	?																					?	?	?	?	?																																?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	K	P	I	T	G	T	H	A	E	H	R	Q	V	V	D	Q	L	A	T	L	L	R	T	P	Q	R	A	P	G	Y	E	E	E	W	N	V	F	R	T	V	L	E	A	H	A	D	V	E	E	R	D	M	I	P	A	P	T	P	V
Secondary structure
SS confidence
Disorder		?	?																					?	?	?	?	?	?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.
Sequence		H	I	T	D	A	E	L	E	E	L	G	D	K	M	A	A	R	I	E	Q	L	R	G	S	P	L	Y	T	L	R	T	K	G	K	A	D	L	L	K	A	I
Secondary structure
SS confidence
Disorder		?	?	?																			?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 87%) Beta strand ( 0%)

Rank Aligned region

PDB 2p0n chain A Region: 2 - 140 Aligned: 137 Modelled: 139 Confidence: 99.8% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein nmb1532; PDBTitle: nmb1532 protein from neisseria meningitidis, unknown function Phyre2 PDB 3v5y chain C Region: 2 - 137 Aligned: 135 Modelled: 136 Confidence: 99.8% Identity: 16% PDB header:gene regulation Chain: C: PDB Molecule:f-box/lrr-repeat protein 5; PDBTitle: structure of fbxl5 hemerythrin domain, p2(1) cell Phyre2 PDB 5fnp chain B Region: 6 - 117 Aligned: 112 Modelled: 112 Confidence: 99.5% Identity: 20% PDB header:oxidoreductase Chain: B: PDB Molecule:iron-sulfur cluster repair protein ytfe; PDBTitle: high resolution zn containing iron sulfur cluster repair2 protein ytfe Phyre2 PDB 2awy chain B Region: 4 - 123 Aligned: 117 Modelled: 120 Confidence: 97.8% Identity: 15% PDB header:oxygen storage/transport Chain: B: PDB Molecule:hemerythrin-like domain protein dcrh; PDBTitle: met-dcrh-hr Phyre2 PDB 4xpy chain A Region: 3 - 118 Aligned: 113 Modelled: 116 Confidence: 97.5% Identity: 18% PDB header:oxygen binding protein Chain: A: PDB Molecule:bacteriohemerythrin; PDBTitle: crystal structure of hemerythrin : l114y mutant Phyre2 PDB 3cax chain A Region: 4 - 134 Aligned: 130 Modelled: 131 Confidence: 97.4% Identity: 11% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pf0695; PDBTitle: crystal structure of uncharacterized protein pf0695 Phyre2 PDB 1i4y chain A Region: 3 - 109 Aligned: 89 Modelled: 102 Confidence: 92.7% Identity: 16% Fold: Four-helical up-and-down bundle Superfamily: Hemerythrin-like Family: Hemerythrin-like Phyre2 PDB 2mhr chain A Region: 4 - 115 Aligned: 99 Modelled: 107 Confidence: 92.7% Identity: 12% Fold: Four-helical up-and-down bundle Superfamily: Hemerythrin-like Family: Hemerythrin-like Phyre2 PDB 2hmz chain A Region: 4 - 109 Aligned: 88 Modelled: 101 Confidence: 92.0% Identity: 17% Fold: Four-helical up-and-down bundle Superfamily: Hemerythrin-like Family: Hemerythrin-like Phyre2 PDB 1hrb chain A Region: 4 - 109 Aligned: 88 Modelled: 106 Confidence: 80.3% Identity: 17% Fold: Four-helical up-and-down bundle Superfamily: Hemerythrin-like Family: Hemerythrin-like Phyre2 PDB 4rd8 chain B Region: 75 - 120 Aligned: 36 Modelled: 46 Confidence: 52.6% Identity: 25% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of a functionally-unknown protein from2 legionella pneumophila subsp. pneumophila str. philadelphia 1 Phyre2 PDB 3qzc chain A Region: 72 - 145 Aligned: 73 Modelled: 74 Confidence: 19.1% Identity: 15% PDB header:signaling protein Chain: A: PDB Molecule:periplasmic protein cpxp; PDBTitle: structure of the periplasmic stress response protein cpxp Phyre2 PDB 1dd4 chain D Region: 122 - 146 Aligned: 25 Modelled: 25 Confidence: 11.2% Identity: 28% Fold: Ribosomal protein L7/12, oligomerisation (N-terminal) domain Superfamily: Ribosomal protein L7/12, oligomerisation (N-terminal) domain Family: Ribosomal protein L7/12, oligomerisation (N-terminal) domain Phyre2 PDB 2gaa chain A Region: 121 - 161 Aligned: 38 Modelled: 41 Confidence: 11.1% Identity: 29% PDB header:unknown function Chain: A: PDB Molecule:hypothetical 39.9 kda protein; PDBTitle: crystal structure of yfh7 from saccharomyces cerevisiae: a2 putative p-loop containing kinase with a circular3 permutation. Phyre2 PDB 1jhg chain A Region: 88 - 135 Aligned: 45 Modelled: 48 Confidence: 10.9% Identity: 22% Fold: DNA/RNA-binding 3-helical bundle Superfamily: TrpR-like Family: Trp repressor, TrpR Phyre2 PDB 3j47 chain O Region: 125 - 137 Aligned: 13 Modelled: 13 Confidence: 10.0% Identity: 54% PDB header:protein binding Chain: O: PDB Molecule:26s proteasome regulatory subunit rpn9; PDBTitle: formation of an intricate helical bundle dictates the assembly of the2 26s proteasome lid Phyre2 PDB 5hyp chain B Region: 2 - 24 Aligned: 23 Modelled: 23 Confidence: 9.8% Identity: 26% PDB header:immune system Chain: B: PDB Molecule:m28 protein; PDBTitle: structure of human c4b-binding protein alpha cain ccp domains 1 and 22 in complex with the hypervariable region of group a streptococcus m283 protein Phyre2 PDB 5wxm chain V Region: 7 - 21 Aligned: 15 Modelled: 15 Confidence: 9.5% Identity: 20% PDB header:ribosomal protein Chain: V: PDB Molecule:u3 small nucleolar rna-associated protein mpp10; PDBTitle: crystal structure of the imp3 and mpp10 complex Phyre2 PDB 1trr chain A Region: 88 - 135 Aligned: 45 Modelled: 48 Confidence: 7.7% Identity: 24% Fold: DNA/RNA-binding 3-helical bundle Superfamily: TrpR-like Family: Trp repressor, TrpR Phyre2 PDB 3itf chain A Region: 72 - 142 Aligned: 70 Modelled: 71 Confidence: 7.1% Identity: 16% PDB header:signaling protein Chain: A: PDB Molecule:periplasmic adaptor protein cpxp; PDBTitle: structural basis for the inhibitory function of the cpxp adaptor2 protein Phyre2 1 c2p0nA_ 2 c3v5yC_ 3 c5fnpB_ 4 c2awyB_ 5 c4xpyA_ 6 c3caxA_ 7 d1i4ya_ 8 d2mhra_ 9 d2hmza_ 10 d1hrba_ 11 c4rd8B_ 12 c3qzcA_ 13 d1dd4d_ 14 c2gaaA_ 15 d1jhga_ 16 c3j47O_ 17 c5hypB_ 18 c5wxmV_ 19 d1trra_ 20 c3itfA_ 21 22 23 24 25