1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	V	V	R	S	I	L	L	F	V	L	A	A	V	A	E	I	G	G	A	W	L	V	W	Q	G	V	R	E	Q	R	G	W	L	W	A	G	L	G	V	I	A	L	G	V	Y	G	F	F	A	T	L	Q	P	D	A	H	F	G	R
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110
Sequence		V	L	A	A	Y	G	G	V	F	V	A	G	S	L	A	W	G	M	A	L	D	G	F	R	P	D	R	W	D	V	I	G	A	L	G	C	M	A	G	V	A	V	I	M	Y	A	P	R	G	H
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 85%) Beta strand ( 0%) TM helix ( 60%) (View membrane topology prediction)

Rank Aligned region

PDB 1s7b chain A Region: 10 - 110 Aligned: 100 Modelled: 101 Confidence: 95.6% Identity: 24% Fold: Multidrug resistance efflux transporter EmrE Superfamily: Multidrug resistance efflux transporter EmrE Family: Multidrug resistance efflux transporter EmrE Phyre2 PDB 5i20 chain E Region: 36 - 108 Aligned: 69 Modelled: 73 Confidence: 87.6% Identity: 16% PDB header:membrane protein Chain: E: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein Phyre2 PDB 5i20 chain C Region: 63 - 108 Aligned: 46 Modelled: 46 Confidence: 78.9% Identity: 15% PDB header:membrane protein Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein Phyre2 PDB 6gs7 chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 75.9% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:dipeptide and tripeptide permease a; PDBTitle: crystal structure of peptide transporter dtpa-nanobody in glycine2 buffer Phyre2 PDB 4iky chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 69.3% Identity: 20% PDB header:transport protein Chain: A: PDB Molecule:di-tripeptide abc transporter (permease); PDBTitle: crystal structure of peptide transporter pot (e310q mutant) in complex2 with sulfate Phyre2 PDB 4lep chain B Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 66.0% Identity: 19% PDB header:membrane protein, tranport protein Chain: B: PDB Molecule:proton:oligopeptide symporter pot family; PDBTitle: structural insights into substrate recognition in proton dependent2 oligopeptide transporters Phyre2 PDB 4q65 chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 65.5% Identity: 20% PDB header:transport protein Chain: A: PDB Molecule:dipeptide permease d; PDBTitle: structure of the e. coli peptide transporter ybgh Phyre2 PDB 4w6v chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 63.1% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:di-/tripeptide transporter; PDBTitle: crystal structure of a peptide transporter from yersinia2 enterocolitica at 3 a resolution Phyre2 PDB 6oh2 chain A Region: 2 - 103 Aligned: 102 Modelled: 102 Confidence: 56.3% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:cmp-sialic acid transporter; PDBTitle: x-ray crystal structure of the mouse cmp-sialic acid transporter in2 complex with cmp, by lipidic cubic phase Phyre2 PDB 4cl5 chain B Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 46.6% Identity: 19% PDB header:transport protein Chain: B: PDB Molecule:nitrate transporter 1.1; PDBTitle: crystal structure of the nitrate transporter nrt1.1 from2 arabidopsis thaliana in complex with nitrate. Phyre2 PDB 4aps chain B Region: 31 - 107 Aligned: 77 Modelled: 77 Confidence: 43.9% Identity: 22% PDB header:transport protein Chain: B: PDB Molecule:di-or tripeptide h+ symporter; PDBTitle: crystal structure of a pot family peptide transporter in an inward2 open conformation. Phyre2 PDB 6exs chain A Region: 4 - 107 Aligned: 88 Modelled: 88 Confidence: 43.7% Identity: 17% PDB header:membrane protein Chain: A: PDB Molecule:peptide abc transporter permease; PDBTitle: crystal structure of a pot family transporter in complex with2 thioalcohol conjugated peptide. Phyre2 PDB 6i1r chain A Region: 24 - 107 Aligned: 84 Modelled: 84 Confidence: 43.5% Identity: 11% PDB header:membrane protein Chain: A: PDB Molecule:cmp-sialic acid transporter 1; PDBTitle: crystal structure of cmp bound cst in an outward facing conformation Phyre2 PDB 6e9o chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 41.7% Identity: 19% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 3wdo chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 40.5% Identity: 19% PDB header:transport protein Chain: A: PDB Molecule:mfs transporter; PDBTitle: structure of e. coli yajr transporter Phyre2 PDB 3o7p chain A Region: 31 - 107 Aligned: 77 Modelled: 77 Confidence: 37.3% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:l-fucose-proton symporter; PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a) Phyre2 PDB 6ei3 chain A Region: 55 - 109 Aligned: 55 Modelled: 55 Confidence: 36.9% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:proton-dependent oligopeptide transporter family protein; PDBTitle: crystal structure of auto inhibited pot family peptide transporter Phyre2 PDB 4iu9 chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 36.7% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:nitrite extrusion protein 2; PDBTitle: crystal structure of a membrane transporter Phyre2 PDB 1pv7 chain B Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 31.3% Identity: 13% PDB header:transport protein Chain: B: PDB Molecule:lactose permease; PDBTitle: crystal structure of lactose permease with tdg Phyre2 PDB 1pv7 chain A Region: 54 - 107 Aligned: 54 Modelled: 54 Confidence: 31.3% Identity: 13% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: LacY-like proton/sugar symporter Phyre2 1 d1s7ba_ 2 c5i20E_ 3 c5i20C_ 4 c6gs7A_ 5 c4ikyA_ 6 c4lepB_ 7 c4q65A_ 8 c4w6vA_ 9 c6oh2A_ 10 c4cl5B_ 11 c4apsB_ 12 c6exsA_ 13 c6i1rA_ 14 c6e9oA_ 15 c3wdoA_ 16 c3o7pA_ 17 c6ei3A_ 18 c4iu9A_ 19 c1pv7B_ 20 d1pv7a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50