1

.

.

.

.

.

.

.

.

10

.

.

.

.

.

.

.

.

.

20

.

.

.

.

.

.

.

.

.

30

.

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

Sequence

M

T

A

V

G

G

S

P

P

T

R

R

C

P

A

T

E

D

R

A

P

A

T

V

A

T

P

S

S

T

D

P

T

A

S

R

A

V

S

W

W

S

V

H

E

Y

V

A

P

T

L

A

A

A

V

E

W

P

M

A

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

Sequence

G

T

P

A

W

C

D

L

D

D

T

D

P

V

K

W

A

A

I

C

D

A

A

R

H

W

A

L

R

V

E

T

C

Q

A

A

S

A

E

A

S

R

D

V

S

A

A

A

D

W

P

A

V

S

R

E

I

Q

R

R

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

130

Sequence

R

D

A

Y

I

R

R

V

V

V

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 39%) Alpha helix ( 68%) Beta strand ( 0%)

Rank Aligned region

PDB 2m0n chain A Region: 47 - 63 Aligned: 16 Modelled: 17 Confidence: 17.0% Identity: 56% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution structure of a duf3349 annotated protein from mycobacterium2 abscessus, mab_3403c. seattle structural genomics center for3 infectious disease target myaba.17112.a.a2 Phyre2 PDB 2jt1 chain A Region: 69 - 83 Aligned: 15 Modelled: 15 Confidence: 15.9% Identity: 60% PDB header:transcription Chain: A: PDB Molecule:pefi protein; PDBTitle: solution nmr structure of pefi (plasmid-encoded fimbriae regulatory)2 protein from salmonella typhimurium. northeast structural genomics3 target str82 Phyre2 PDB 4n3x chain D Region: 91 - 119 Aligned: 29 Modelled: 29 Confidence: 14.2% Identity: 28% PDB header:endocytosis Chain: D: PDB Molecule:rab5 gdp/gtp exchange factor; PDBTitle: crystal structure of rabex-5 cc domain Phyre2 PDB 3vza chain E Region: 64 - 77 Aligned: 14 Modelled: 14 Confidence: 13.6% Identity: 36% PDB header:cell cycle Chain: E: PDB Molecule:centromere protein t; PDBTitle: crystal structure of the chicken spc24-spc25 globular domain in2 complex with cenp-t peptide Phyre2 PDB 3vza chain F Region: 64 - 77 Aligned: 14 Modelled: 14 Confidence: 13.6% Identity: 36% PDB header:cell cycle Chain: F: PDB Molecule:centromere protein t; PDBTitle: crystal structure of the chicken spc24-spc25 globular domain in2 complex with cenp-t peptide Phyre2 PDB 2mv6 chain A Region: 19 - 32 Aligned: 14 Modelled: 14 Confidence: 11.6% Identity: 43% PDB header:membrane protein Chain: A: PDB Molecule:erythropoietin receptor; PDBTitle: solution structure of the transmembrane domain and the juxta-membrane2 domain of the erythropoietin receptor in micelles Phyre2 PDB 2g7r chain A Region: 61 - 68 Aligned: 8 Modelled: 8 Confidence: 11.1% Identity: 50% PDB header:hydrolase Chain: A: PDB Molecule:mucosa-associated lymphoid tissue lymphoma translocation PDBTitle: x-ray structure of the death domain of the human mucosa associated2 lymphoid tissue lymphoma translocation protein 1 Phyre2 PDB 2jp6 chain A Region: 90 - 100 Aligned: 11 Modelled: 11 Confidence: 10.1% Identity: 64% PDB header:toxin Chain: A: PDB Molecule:potassium channel toxin alpha-ktx 18.1; PDBTitle: structural and functional characterization of the2 recombinant form of the kv1.3 channel blocker tc32 Phyre2 PDB 1ejx chain C domain 2 Region: 27 - 33 Aligned: 7 Modelled: 7 Confidence: 8.4% Identity: 86% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: alpha-subunit of urease, catalytic domain Phyre2 PDB 1e9y chain B domain 2 Region: 27 - 33 Aligned: 7 Modelled: 7 Confidence: 8.2% Identity: 71% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: alpha-subunit of urease, catalytic domain Phyre2 PDB 3gw6 chain F Region: 68 - 103 Aligned: 36 Modelled: 36 Confidence: 6.6% Identity: 25% PDB header:chaperone Chain: F: PDB Molecule:endo-n-acetylneuraminidase; PDBTitle: intramolecular chaperone Phyre2 PDB 5e06 chain A Region: 83 - 127 Aligned: 40 Modelled: 45 Confidence: 6.0% Identity: 23% PDB header:nuclear protein Chain: A: PDB Molecule:nucleocapsid protein; PDBTitle: structure of sin nombre virus nucleoprotein in long-axis crystal form Phyre2 1 c2m0nA_ 2 c2jt1A_ 3 c4n3xD_ 4 c3vzaE_ 5 c3vzaF_ 6 c2mv6A_ 7 c2g7rA_ 8 c2jp6A_ 9 d1ejxc2 10 d1e9yb2 11 c3gw6F_ 12 c5e06A_