1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	E	V	R	A	S	A	R	K	H	G	I	N	D	D	A	M	L	H	A	Y	R	N	A	L	R	Y	V	E	L	E	Y	H	G	E	V	Q	L	L	V	I	G	P	D	Q	T	G	R	L	L	E	L	V	I	P	A	D	E	P	P
Secondary structure
SS confidence
Disorder		?	?	?	?						?		?																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.
Sequence		R	I	I	H	A	N	V	L	R	P	K	F	Y	D	Y	L	R
Secondary structure
SS confidence
Disorder																	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 34%) Beta strand ( 34%)

Rank Aligned region

PDB 3u97 chain A Region: 5 - 70 Aligned: 63 Modelled: 66 Confidence: 96.1% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease toxin brnt; PDBTitle: 1.1 angstrom-resolution crystal structure of the brucella abortus2 ribonuclease toxin, brnt Phyre2 PDB 3su8 chain X Region: 7 - 21 Aligned: 15 Modelled: 15 Confidence: 76.3% Identity: 40% PDB header:apoptosis/signaling protein Chain: X: PDB Molecule:plexin-b1; PDBTitle: crystal structure of a truncated intracellular domain of plexin-b1 in2 complex with rac1 Phyre2 PDB 4m8n chain B Region: 7 - 21 Aligned: 15 Modelled: 15 Confidence: 75.5% Identity: 33% PDB header:signaling protein Chain: B: PDB Molecule:plexinc1 intracellular region; PDBTitle: crystal structure of plexinc1/rap1b complex Phyre2 PDB 3hm6 chain X Region: 7 - 21 Aligned: 15 Modelled: 15 Confidence: 74.9% Identity: 40% PDB header:signaling protein Chain: X: PDB Molecule:plexin-b1; PDBTitle: crystal structure of the cytoplasmic domain of human plexin b1 Phyre2 PDB 5e6p chain A Region: 7 - 21 Aligned: 15 Modelled: 15 Confidence: 74.3% Identity: 40% PDB header:signaling protein Chain: A: PDB Molecule:plexin-b2; PDBTitle: plexinb2 cytoplasmic region/pdz-rhogef pdz domain complex Phyre2 PDB 5v6r chain B Region: 7 - 21 Aligned: 15 Modelled: 15 Confidence: 73.8% Identity: 47% PDB header:protein binding Chain: B: PDB Molecule:plexin-d1; PDBTitle: structure of plexin d1 intracellular domain Phyre2 PDB 3ig3 chain A Region: 7 - 21 Aligned: 15 Modelled: 15 Confidence: 72.5% Identity: 27% PDB header:signaling protein, membrane protein Chain: A: PDB Molecule:plxna3 protein; PDBTitle: crystal structure of mouse plexin a3 intracellular domain Phyre2 PDB 3bey chain C Region: 5 - 24 Aligned: 20 Modelled: 20 Confidence: 39.3% Identity: 25% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:conserved protein o27018; PDBTitle: crystal structure of the protein o27018 from methanobacterium2 thermoautotrophicum. northeast structural genomics consortium target3 tt217 Phyre2 PDB 1p8c chain D Region: 7 - 24 Aligned: 18 Modelled: 18 Confidence: 33.8% Identity: 22% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of tm1620 (apc4843) from thermotoga2 maritima Phyre2 PDB 6bqz chain A Region: 10 - 48 Aligned: 29 Modelled: 39 Confidence: 30.2% Identity: 24% PDB header:ligase Chain: A: PDB Molecule:tyrosine--trna ligase; PDBTitle: crystal structure of tyrosine-trna synthetase from acinetobacter2 baumannii with bound l-tyrosine Phyre2 PDB 5dip chain B Region: 4 - 25 Aligned: 22 Modelled: 22 Confidence: 28.8% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:alkyl hydroperoxide reductase ahpd; PDBTitle: crystal structure of lpg0406 in reduced form from legionella2 pneumophila Phyre2 PDB 3jxe chain B Region: 15 - 49 Aligned: 25 Modelled: 35 Confidence: 26.9% Identity: 36% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp Phyre2 PDB 2ouw chain A domain 1 Region: 4 - 22 Aligned: 19 Modelled: 19 Confidence: 24.2% Identity: 21% Fold: AhpD-like Superfamily: AhpD-like Family: TTHA0727-like Phyre2 PDB 3gwr chain A Region: 42 - 65 Aligned: 24 Modelled: 24 Confidence: 24.1% Identity: 8% PDB header:protein binding Chain: A: PDB Molecule:putative calcium/calmodulin-dependent protein kinase type PDBTitle: crystal structure of putative calcium/calmodulin-dependent protein2 kinase type ii association domain (yp_315894.1) from thiobacillus3 denitrificans atcc 25259 at 2.00 a resolution Phyre2 PDB 2qeu chain A Region: 5 - 25 Aligned: 21 Modelled: 21 Confidence: 22.9% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:putative carboxymuconolactone decarboxylase; PDBTitle: crystal structure of putative carboxymuconolactone decarboxylase2 (yp_555818.1) from burkholderia xenovorans lb400 at 1.65 a resolution Phyre2 PDB 1knc chain A Region: 4 - 24 Aligned: 21 Modelled: 21 Confidence: 22.3% Identity: 24% Fold: AhpD-like Superfamily: AhpD-like Family: AhpD Phyre2 PDB 1vke chain A Region: 5 - 22 Aligned: 18 Modelled: 18 Confidence: 21.6% Identity: 17% Fold: AhpD-like Superfamily: AhpD-like Family: CMD-like Phyre2 PDB 2p7p chain B Region: 18 - 61 Aligned: 43 Modelled: 44 Confidence: 21.5% Identity: 19% PDB header:metal binding protein, hydrolase Chain: B: PDB Molecule:glyoxalase family protein; PDBTitle: crystal structure of genomically encoded fosfomycin resistance2 protein, fosx, from listeria monocytogenes complexed with mn(ii) and3 sulfate ion Phyre2 PDB 1vke chain B Region: 5 - 24 Aligned: 20 Modelled: 20 Confidence: 18.6% Identity: 20% Fold: AhpD-like Superfamily: AhpD-like Family: CMD-like Phyre2 PDB 2pid chain B Region: 32 - 50 Aligned: 19 Modelled: 19 Confidence: 17.9% Identity: 26% PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of human mitochondrial tyrosyl-trna synthetase in2 complex with an adenylate analog Phyre2 1 c3u97A_ 2 c3su8X_ 3 c4m8nB_ 4 c3hm6X_ 5 c5e6pA_ 6 c5v6rB_ 7 c3ig3A_ 8 c3beyC_ 9 c1p8cD_ 10 c6bqzA_ 11 c5dipB_ 12 c3jxeB_ 13 d2ouwa1 14 c3gwrA_ 15 c2qeuA_ 16 d1knca_ 17 d1vkea_ 18 c2p7pB_ 19 d1vkeb_ 20 c2pidB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99