1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	R	L	V	P	A	L	R	L	E	L	T	L	Q	V	R	Q	K	F	L	H	A	A	V	F	S	G	L	I	W	L	A	V	L	L	P	M	P	V	S	L	R	P	V	A	E	P	Y	V	L	V	G	D	I	A	I	I	G	F
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	F	V	G	G	T	V	F	F	E	K	Q	E	R	T	I	G	A	I	V	S	T	P	L	R	F	W	E	Y	L	A	A	K	L	T	V	L	L	A	I	S	L	F	V	A	V	V	V	A	T	I	V	H	G	L	G	Y	H	L	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	L	V	A	G	I	V	L	G	T	L	L	M	L	L	V	G	F	S	S	S	L	P	F	A	S	V	T	D	W	F	L	A	A	V	I	P	L	A	I	M	L	A	P	P	V	V	H	Y	S	G	L	W	P	N	P	V	L	Y	L
Secondary structure
SS confidence
Disorder																																																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Sequence		I	P	T	Q	G	P	L	L	L	L	G	A	A	F	D	Q	V	S	L	A	P	W	Q	V	G	Y	A	V	V	Y	P	I	V	C	A	A	G	L	C	R	A	A	K	A	L	F	G	R	Y	V	V	Q	R	S	G	V	L
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?																																	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 87%) Beta strand ( 0%) TM helix ( 64%) (View membrane topology prediction)

Rank Aligned region

PDB 6an7 chain D Region: 1 - 232 Aligned: 227 Modelled: 232 Confidence: 99.9% Identity: 10% PDB header:transport protein Chain: D: PDB Molecule:transport permease protein; PDBTitle: crystal structure of o-antigen polysaccharide abc-transporter Phyre2 PDB 6an7 chain C Region: 1 - 232 Aligned: 224 Modelled: 229 Confidence: 99.9% Identity: 10% PDB header:transport protein Chain: C: PDB Molecule:transport permease protein; PDBTitle: crystal structure of o-antigen polysaccharide abc-transporter Phyre2 PDB 5do7 chain B Region: 1 - 234 Aligned: 234 Modelled: 234 Confidence: 99.8% Identity: 8% PDB header:transport protein Chain: B: PDB Molecule:atp-binding cassette sub-family g member 8; PDBTitle: crystal structure of the human sterol transporter abcg5/abcg8 Phyre2 PDB 5nj3 chain B Region: 2 - 229 Aligned: 228 Modelled: 228 Confidence: 99.8% Identity: 13% PDB header:transport protein Chain: B: PDB Molecule:atp-binding cassette sub-family g member 2; PDBTitle: structure of an abc transporter: complete structure Phyre2 PDB 5njg chain B Region: 1 - 232 Aligned: 232 Modelled: 232 Confidence: 99.7% Identity: 10% PDB header:transport protein Chain: B: PDB Molecule:atp-binding cassette sub-family g member 2; PDBTitle: structure of an abc transporter: part of the structure that could be2 built de novo Phyre2 PDB 5do7 chain A Region: 2 - 229 Aligned: 228 Modelled: 228 Confidence: 99.7% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:atp-binding cassette sub-family g member 5; PDBTitle: crystal structure of the human sterol transporter abcg5/abcg8 Phyre2 PDB 5xjy chain A Region: 41 - 225 Aligned: 184 Modelled: 185 Confidence: 98.8% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:atp-binding cassette sub-family a member 1; PDBTitle: cryo-em structure of human abca1 Phyre2 PDB 1ifl chain A Region: 185 - 232 Aligned: 47 Modelled: 48 Confidence: 27.2% Identity: 13% PDB header:virus Chain: A: PDB Molecule:inovirus; PDBTitle: molecular models and structural comparisons of native and2 mutant class i filamentous bacteriophages ff (fd, f1, m13),3 if1 and ike Phyre2 PDB 6but chain B Region: 217 - 234 Aligned: 18 Modelled: 18 Confidence: 20.9% Identity: 11% PDB header:membrane protein Chain: B: PDB Molecule:sodium channel protein type 2 subunit alpha; PDBTitle: solution structure of full-length apo mammalian calmodulin bound to2 the iq motif of the human voltage-gated sodium channel nav1.2 Phyre2 PDB 2m5e chain B Region: 217 - 234 Aligned: 18 Modelled: 18 Confidence: 20.4% Identity: 11% PDB header:calcium-binding protein/metal transport Chain: B: PDB Molecule:sodium channel protein type 2 subunit alpha; PDBTitle: structure of the c-domain of calcium-saturated calmodulin bound to the2 iq motif of nav1.2 Phyre2 PDB 2kxw chain B Region: 217 - 234 Aligned: 18 Modelled: 18 Confidence: 20.4% Identity: 11% PDB header:calcium-binding protein/metal transport Chain: B: PDB Molecule:sodium channel protein type 2 subunit alpha; PDBTitle: structure of the c-domain fragment of apo calmodulin bound to the iq2 motif of nav1.2 Phyre2 PDB 5lj7 chain B Region: 43 - 150 Aligned: 108 Modelled: 108 Confidence: 17.7% Identity: 6% PDB header:transport protein Chain: B: PDB Molecule:macrolide export atp-binding/permease protein macb; PDBTitle: structure of aggregatibacter actinomycetemcomitans macb bound to atp2 (p21) Phyre2 PDB 2bbj chain B Region: 139 - 225 Aligned: 60 Modelled: 60 Confidence: 10.5% Identity: 13% PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter Phyre2 PDB 2hoe chain A domain 1 Region: 74 - 89 Aligned: 16 Modelled: 16 Confidence: 10.5% Identity: 25% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: ROK associated domain Phyre2 PDB 2l53 chain B Region: 217 - 234 Aligned: 18 Modelled: 18 Confidence: 10.3% Identity: 28% PDB header:ca-binding protein/proton transport Chain: B: PDB Molecule:voltage-gated sodium channel type v alpha isoform b PDBTitle: solution nmr structure of apo-calmodulin in complex with the iq motif2 of human cardiac sodium channel nav1.5 Phyre2 PDB 2r6g chain G domain 1 Region: 144 - 236 Aligned: 93 Modelled: 93 Confidence: 8.6% Identity: 12% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 5ir6 chain B Region: 11 - 228 Aligned: 196 Modelled: 207 Confidence: 6.2% Identity: 13% PDB header:oxidoreductase Chain: B: PDB Molecule:bd-type quinol oxidase subunit ii; PDBTitle: the structure of bd oxidase from geobacillus thermodenitrificans Phyre2 PDB 2cpb chain A Region: 205 - 234 Aligned: 30 Modelled: 30 Confidence: 5.2% Identity: 13% PDB header:viral protein Chain: A: PDB Molecule:m13 major coat protein; PDBTitle: solution nmr structures of the major coat protein of2 filamentous bacteriophage m13 solubilized in3 dodecylphosphocholine micelles, 25 lowest energy structures Phyre2 1 c6an7D_ 2 c6an7C_ 3 c5do7B_ 4 c5nj3B_ 5 c5njgB_ 6 c5do7A_ 7 c5xjyA_ 8 c1iflA_ 9 c6butB_ 10 c2m5eB_ 11 c2kxwB_ 12 c5lj7B_ 13 c2bbjB_ 14 d2hoea1 15 c2l53B_ 16 d2r6gg1 17 c5ir6B_ 18 c2cpbA_