1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	G	T	R	L	A	P	H	S	V	R	Y	R	E	R	L	W	V	P	W	W	W	W	P	L	A	F	A	L	A	A	L	I	A	F	E	V	N	L	G	V	A	A	L	P	D	W	V	P	F	A	T	L	F	T	V	A	A	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?																													?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	L	L	W	L	G	R	V	E	I	R	V	T	A	G	S	A	D	G	A	G	V	K	L	W	A	G	P	A	H	L	P	V	A	V	I	A	R	S	A	E	I	P	A	T	A	K	S	A	A	L	G	R	Q	L	D	P	A	A	Y
Secondary structure
SS confidence
Disorder								?	?					?	?	?	?	?	?	?	?	?																					?	?									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.
Sequence		V	L	H	R	A	W	V	G	P	M	V	L	V	V	L	D	D	P	N	D	P	T	P	Y	W	L	V	S	C	R	H	P	E	R	V	L	S	A	L	R	S
Secondary structure
SS confidence
Disorder																																									?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 39%) Beta strand ( 27%) TM helix ( 17%) (View membrane topology prediction)

Rank Aligned region

PDB 5b0h chain B Region: 125 - 144 Aligned: 20 Modelled: 20 Confidence: 56.9% Identity: 30% PDB header:metal binding protein Chain: B: PDB Molecule:leukocyte cell-derived chemotaxin-2; PDBTitle: crystal structure of human leukocyte cell-derived chemotaxin 2 Phyre2 PDB 6hwh chain X Region: 18 - 63 Aligned: 43 Modelled: 46 Confidence: 49.7% Identity: 19% PDB header:electron transport Chain: X: PDB Molecule:cytochrome c oxidase polypeptide 4; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 1mtp chain B Region: 134 - 143 Aligned: 10 Modelled: 10 Confidence: 37.4% Identity: 50% PDB header:structural genomics Chain: B: PDB Molecule:serine proteinase inhibitor (serpin), chain b; PDBTitle: the x-ray crystal structure of a serpin from a thermophilic prokaryote Phyre2 PDB 1wjr chain A Region: 132 - 148 Aligned: 17 Modelled: 17 Confidence: 29.6% Identity: 47% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: MBT repeat Phyre2 PDB 1oi1 chain A domain 2 Region: 127 - 148 Aligned: 22 Modelled: 22 Confidence: 29.2% Identity: 9% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: MBT repeat Phyre2 PDB 3q0x chain A Region: 128 - 141 Aligned: 14 Modelled: 14 Confidence: 24.5% Identity: 7% PDB header:structural protein Chain: A: PDB Molecule:centriole protein; PDBTitle: n-terminal coiled-coil dimer domain of c. reinhardtii sas-6 homolog2 bld12p Phyre2 PDB 1oz3 chain C Region: 127 - 148 Aligned: 22 Modelled: 22 Confidence: 22.2% Identity: 18% PDB header:transcription Chain: C: PDB Molecule:lethal(3)malignant brain tumor-like protein; PDBTitle: crystal structure of 3-mbt repeats of lethal (3) malignant brain tumor2 (native-i) at 1.85 angstrom Phyre2 PDB 3ut1 chain A Region: 127 - 148 Aligned: 22 Modelled: 22 Confidence: 21.5% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:lethal(3)malignant brain tumor-like protein 3; PDBTitle: crystal structure of the 3-mbt repeat domain of l3mbtl3 Phyre2 PDB 3cey chain A Region: 127 - 148 Aligned: 20 Modelled: 22 Confidence: 19.4% Identity: 25% PDB header:transcription regulator Chain: A: PDB Molecule:lethal(3)malignant brain tumor-like 2 protein; PDBTitle: crystal structure of l3mbtl2 Phyre2 PDB 1px5 chain A domain 1 Region: 132 - 142 Aligned: 11 Modelled: 11 Confidence: 18.8% Identity: 55% Fold: PAP/OAS1 substrate-binding domain Superfamily: PAP/OAS1 substrate-binding domain Family: 2'-5'-oligoadenylate synthetase 1, OAS1, second domain Phyre2 PDB 3q0y chain A Region: 129 - 141 Aligned: 13 Modelled: 13 Confidence: 18.8% Identity: 8% PDB header:structural protein Chain: A: PDB Molecule:centriole protein; PDBTitle: n-terminal domain of c. reinhardtii sas-6 homolog bld12p Phyre2 PDB 4ckm chain A Region: 128 - 141 Aligned: 14 Modelled: 14 Confidence: 15.1% Identity: 57% PDB header:structural protein Chain: A: PDB Molecule:sas-6; PDBTitle: structure of the n-terminal domain of leishmania sas-6 Phyre2 PDB 4ckn chain A Region: 128 - 141 Aligned: 14 Modelled: 14 Confidence: 15.0% Identity: 57% PDB header:structural protein Chain: A: PDB Molecule:sas-6; PDBTitle: structure of an n-terminal fragment of leishmania sas-6 containing2 parts of its coiled coil domain, f257e mutant Phyre2 PDB 3h6z chain A Region: 128 - 148 Aligned: 21 Modelled: 21 Confidence: 14.3% Identity: 10% PDB header:transcription Chain: A: PDB Molecule:polycomb protein sfmbt; PDBTitle: crystal structure of the four mbt repeats of drosophila melanogaster2 sfmbt in complex with peptide rhr (me)k vlr Phyre2 PDB 1px5 chain A Region: 132 - 142 Aligned: 11 Modelled: 11 Confidence: 13.9% Identity: 55% PDB header:transferase Chain: A: PDB Molecule:2'-5'-oligoadenylate synthetase 1; PDBTitle: crystal structure of the 2'-specific and double-stranded2 rna-activated interferon-induced antiviral protein 2'-5'-3 oligoadenylate synthetase Phyre2 PDB 2vyt chain A Region: 127 - 148 Aligned: 22 Modelled: 22 Confidence: 13.8% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:sex comb on midleg-like protein 2; PDBTitle: the mbt repeats of human scml2 bind to peptides containing mono2 methylated lysine. Phyre2 PDB 4s3n chain A Region: 132 - 142 Aligned: 11 Modelled: 11 Confidence: 13.7% Identity: 55% PDB header:transferase/rna Chain: A: PDB Molecule:2'-5'-oligoadenylate synthase 3; PDBTitle: crystal structure of human oas3 domain i in complex with dsrna Phyre2 PDB 1oz2 chain A domain 2 Region: 127 - 148 Aligned: 22 Modelled: 22 Confidence: 13.1% Identity: 14% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: MBT repeat Phyre2 PDB 1ky8 chain A Region: 126 - 161 Aligned: 36 Modelled: 36 Confidence: 13.0% Identity: 22% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1wjs chain A Region: 132 - 148 Aligned: 17 Modelled: 17 Confidence: 12.4% Identity: 18% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: MBT repeat Phyre2 1 c5b0hB_ 2 c6hwhX_ 3 c1mtpB_ 4 d1wjra_ 5 d1oi1a2 6 c3q0xA_ 7 c1oz3C_ 8 c3ut1A_ 9 c3ceyA_ 10 d1px5a1 11 c3q0yA_ 12 c4ckmA_ 13 c4cknA_ 14 c3h6zA_ 15 c1px5A_ 16 c2vytA_ 17 c4s3nA_ 18 d1oz2a2 19 d1ky8a_ 20 d1wjsa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54