1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	D	Q	V	P	K	P	H	R	H	H	I	W	R	I	T	R	R	T	L	S	K	S	W	D	D	S	I	F	S	E	S	A	Q	A	A	F	W	S	A	L	S	L	P	P	L	L	L	G	M	L	G	S	L	A	Y	V	A	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	F	G	P	D	T	L	P	A	I	E	K	S	A	L	S	T	A	H	S	F	F	S	P	S	V	V	N	E	I	I	E	P	T	I	G	D	I	T	N	N	A	R	G	E	V	A	S	L	G	F	L	I	S	L	W	A	G	S	S
Secondary structure
SS confidence
Disorder			?	?		?															?	?	?																			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	I	S	A	F	V	D	A	V	V	E	A	H	D	Q	T	P	L	R	H	P	V	R	Q	R	F	F	A	L	F	L	Y	V	V	M	L	V	F	L	V	A	T	A	P	V	M	V	V	G	P	R	K	V	S	E	H	I	P	E	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	A	N	L	L	R	Y	G	Y	Y	P	A	L	I	L	G	L	T	V	G	V	I	L	L	Y	R	V	A	L	P	V	P	L	P	T	H	R	L	V	L	G	A	V	L	A	I	A	V	F	L	I	A	T	L	G	L	R	V	Y	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	W	I	T	R	T	G	Y	T	Y	G	A	L	A	T	P	I	A	F	L	L	F	A	F	F	G	G	F	A	I	M	L	G	A	E	L	N	A	A	V	Q	E	E	W	P	A	P	A	T	H	A	H	R	L	G	N	W	L	K	A
Secondary structure
SS confidence
Disorder																																													?	?	?	?	?	?	?	?	?	?	?	?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.
Sequence		R	I	G	V	G	T	T	T	Y	S	S	T	A	Q	H	S	A	V	A	A	E	P	P	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 77%) Beta strand ( 0%) TM helix ( 44%) (View membrane topology prediction)

Rank Aligned region

PDB 2r6g chain F domain 1 Region: 190 - 247 Aligned: 56 Modelled: 58 Confidence: 94.1% Identity: 20% Fold: MalF N-terminal region-like Superfamily: MalF N-terminal region-like Family: MalF N-terminal region-like Phyre2 PDB 6ezn chain H Region: 129 - 225 Aligned: 92 Modelled: 97 Confidence: 29.7% Identity: 7% PDB header:membrane protein Chain: H: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: cryo-em structure of the yeast oligosaccharyltransferase (ost) complex Phyre2 PDB 2yn9 chain B Region: 246 - 266 Aligned: 21 Modelled: 21 Confidence: 10.9% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:potassium-transporting atpase subunit beta; PDBTitle: cryo-em structure of gastric h+,k+-atpase with bound rubidium Phyre2 PDB 2qks chain A Region: 182 - 270 Aligned: 88 Modelled: 89 Confidence: 10.1% Identity: 17% PDB header:metal transport Chain: A: PDB Molecule:kir3.1-prokaryotic kir channel chimera; PDBTitle: crystal structure of a kir3.1-prokaryotic kir channel chimera Phyre2 PDB 5lnk chain W Region: 36 - 59 Aligned: 24 Modelled: 24 Confidence: 9.5% Identity: 17% PDB header:oxidoreductase Chain: W: PDB Molecule:mitochondrial complex i, sgdh subunit; PDBTitle: entire ovine respiratory complex i Phyre2 PDB 3ech chain C Region: 3 - 16 Aligned: 14 Modelled: 14 Confidence: 9.1% Identity: 21% PDB header:transcription, transcription regulation Chain: C: PDB Molecule:25-mer fragment of protein armr; PDBTitle: the marr-family repressor mexr in complex with its antirepressor armr Phyre2 PDB 3b8e chain B Region: 246 - 265 Aligned: 20 Modelled: 20 Confidence: 8.8% Identity: 20% PDB header:hydrolase/transport protein Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit PDBTitle: crystal structure of the sodium-potassium pump Phyre2 PDB 2voy chain B Region: 2 - 38 Aligned: 36 Modelled: 37 Confidence: 8.2% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium atpase 1; PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus Phyre2 PDB 3ixz chain B Region: 246 - 266 Aligned: 21 Modelled: 21 Confidence: 7.9% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:potassium-transporting atpase subunit beta; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride Phyre2 PDB 2zxe chain B Region: 246 - 266 Aligned: 21 Modelled: 21 Confidence: 7.5% Identity: 19% PDB header:hydrolase/transport protein Chain: B: PDB Molecule:na+,k+-atpase beta subunit; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state Phyre2 PDB 3kdp chain D Region: 246 - 265 Aligned: 20 Modelled: 20 Confidence: 7.1% Identity: 20% PDB header:hydrolase Chain: D: PDB Molecule:sodium/potassium-transporting atpase subunit beta-1; PDBTitle: crystal structure of the sodium-potassium pump Phyre2 PDB 2xzb chain B Region: 246 - 266 Aligned: 21 Modelled: 21 Confidence: 6.6% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:potassium-transporting atpase subunit beta; PDBTitle: pig gastric h,k-atpase with bound bef and sch28080 Phyre2 PDB 1m9d chain C Region: 275 - 323 Aligned: 48 Modelled: 49 Confidence: 5.9% Identity: 17% Fold: Retrovirus capsid protein, N-terminal core domain Superfamily: Retrovirus capsid protein, N-terminal core domain Family: Retrovirus capsid protein, N-terminal core domain Phyre2 PDB 2pxr chain C domain 1 Region: 275 - 323 Aligned: 48 Modelled: 49 Confidence: 5.5% Identity: 19% Fold: Retrovirus capsid protein, N-terminal core domain Superfamily: Retrovirus capsid protein, N-terminal core domain Family: Retrovirus capsid protein, N-terminal core domain Phyre2 1 d2r6gf1 2 c6eznH_ 3 c2yn9B_ 4 c2qksA_ 5 c5lnkW_ 6 c3echC_ 7 c3b8eB_ 8 c2voyB_ 9 c3ixzB_ 10 c2zxeB_ 11 c3kdpD_ 12 c2xzbB_ 13 d1m9dc_ 14 d2pxrc1