1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	L	V	D	E	L	G	V	K	I	V	H	A	Q	H	V	P	A	P	Y	L	V	Q	R	M	R	E	I	H	E	R	D	E	N	R	Q	R	H	A	Q	V	D	V	Q	R	R	R	D	Q	P	E	R	G	Q	H	Q	H	R	R	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																									?	?	?	?	?		?	?	?	?	?	?	?		?	?	?	?	?	?	?	?						?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	D	A	D	H	H	P	D	G	R	T	L	A	G	Q	I	V	A	H	P	V	S	H	R	V	R	Q	P	R	P	V	A	I	A	D	V	L	P	R	V	G	P	R	A	D	C	V	V	A	H	S	L	Q	G	S	P	R	R	R	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?															?					?									?										?			?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	R	R	G	Q	T	A	H	Q	R	L	G	R	R	S	G	N	A	I	A	C	P	L	Y	L	E	N	A	A	G	P	E	P	D	T	K	R	A	E	G	R	R	F	G	A	F	G	G	G	D	L	R	W	M	A	D	R	V	P	R
Secondary structure
SS confidence
Disorder				?	?	?	?					?	?	?	?	?	?										?		?	?	?	?	?	?	?	?	?	?	?	?	?	?		?		?														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	G	S	G	R	R	G	L	G	S	R	S	G	A	G	V	P	Q	G	A	D	A	R	G	W	R	H	T	A	D	G	V	P	R	V	G	Q	P	A	I	R	R	G	V	P	G	F	W	C	W	L	D	H	V	L	T	G	F	G	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
Sequence		R	N	A	I	C	A	I	E	D	G	V	E	P	R	V	A	W	W	A	L	C	T	D	F	D	V	P	R	S	M	G	R	R	T	P	G	G
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 41%) Alpha helix ( 54%) Beta strand ( 3%)

Rank Aligned region

PDB 6dma chain D Region: 21 - 34 Aligned: 14 Modelled: 14 Confidence: 27.0% Identity: 57% PDB header:de novo protein Chain: D: PDB Molecule:dhd15_closed_b; PDBTitle: dhd15_closed Phyre2 PDB 2elp chain A Region: 135 - 148 Aligned: 13 Modelled: 14 Confidence: 19.1% Identity: 46% PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 406; PDBTitle: solution structure of the 13th c2h2 zinc finger of human2 zinc finger protein 406 Phyre2 PDB 2bec chain B Region: 230 - 240 Aligned: 11 Modelled: 11 Confidence: 14.2% Identity: 55% PDB header:metal binding protein/transport protein Chain: B: PDB Molecule:sodium/hydrogen exchanger 1; PDBTitle: crystal structure of chp2 in complex with its binding2 region in nhe1 and insights into the mechanism of ph3 regulation Phyre2 PDB 1b8x chain A domain 1 Region: 145 - 191 Aligned: 46 Modelled: 47 Confidence: 13.9% Identity: 33% Fold: GST C-terminal domain-like Superfamily: GST C-terminal domain-like Family: Glutathione S-transferase (GST), C-terminal domain Phyre2 PDB 6hlw chain B Region: 88 - 100 Aligned: 13 Modelled: 13 Confidence: 12.7% Identity: 54% PDB header:viral protein Chain: B: PDB Molecule:genome polyprotein; PDBTitle: crystal structure of human acbd3 gold domain in complex with 3a2 protein of enterovirus-a71 (fusion protein) Phyre2 PDB 1a6c chain A domain 3 Region: 137 - 175 Aligned: 38 Modelled: 39 Confidence: 11.4% Identity: 13% Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily: Positive stranded ssRNA viruses Family: Comoviridae-like VP Phyre2 PDB 6hlt chain D Region: 88 - 101 Aligned: 14 Modelled: 14 Confidence: 11.4% Identity: 43% PDB header:viral protein Chain: D: PDB Molecule:genome polyprotein; PDBTitle: crystal structure of human acbd3 gold domain in complex with 3a2 protein of rhinovirus-14 (hrv14) Phyre2 PDB 1uus chain A Region: 227 - 235 Aligned: 9 Modelled: 9 Confidence: 11.1% Identity: 33% PDB header:signal transduction Chain: A: PDB Molecule:stat protein; PDBTitle: structure of an activated dictyostelium stat in its2 dna-unbound form Phyre2 PDB 2x3m chain A Region: 144 - 181 Aligned: 38 Modelled: 38 Confidence: 10.1% Identity: 32% PDB header:unknown function Chain: A: PDB Molecule:hypothetical protein orf239; PDBTitle: crystal structure of hypothetical protein orf239 from pyrobaculum2 spherical virus Phyre2 PDB 6hmv chain B Region: 88 - 100 Aligned: 13 Modelled: 13 Confidence: 10.0% Identity: 46% PDB header:viral protein Chain: B: PDB Molecule:genome polyprotein; PDBTitle: crystal structure of human acbd3 gold domain in complex with 3a2 protein of enterovirus-d68 (fusion protein, lvvy mutant) Phyre2 PDB 5o9z chain N Region: 226 - 234 Aligned: 9 Modelled: 9 Confidence: 9.3% Identity: 78% PDB header:splicing Chain: N: PDB Molecule:zinc finger matrin-type protein 2; PDBTitle: cryo-em structure of a pre-catalytic human spliceosome primed for2 activation (b complex) Phyre2 PDB 6hs6 chain E Region: 15 - 32 Aligned: 18 Modelled: 18 Confidence: 9.2% Identity: 28% PDB header:transport protein Chain: E: PDB Molecule:type vi secretion protein impa; PDBTitle: c-terminal domain of the tssa component of the type vi secretion2 system from burkholderia cenocepacia Phyre2 PDB 1ng7 chain A Region: 88 - 100 Aligned: 13 Modelled: 13 Confidence: 8.8% Identity: 46% PDB header:viral protein Chain: A: PDB Molecule:genome polyprotein [core protein p3a]; PDBTitle: the solution structure of the soluble domain of poliovirus2 3a protein Phyre2 PDB 1ng7 chain A Region: 88 - 100 Aligned: 13 Modelled: 13 Confidence: 8.8% Identity: 46% Fold: Soluble domain of poliovirus core protein 3a Superfamily: Soluble domain of poliovirus core protein 3a Family: Soluble domain of poliovirus core protein 3a Phyre2 PDB 1ljz chain B Region: 201 - 207 Aligned: 7 Modelled: 7 Confidence: 8.7% Identity: 57% PDB header:receptor, toxin Chain: B: PDB Molecule:acetylcholine receptor protein; PDBTitle: nmr structure of an achr-peptide (torpedo californica, alpha-subunit2 residues 182-202) in complex with alpha-bungarotoxin Phyre2 PDB 3q66 chain A Region: 219 - 228 Aligned: 10 Modelled: 10 Confidence: 8.3% Identity: 30% PDB header:chaperone/transferase Chain: A: PDB Molecule:vacuolar protein sorting-associated protein 75; PDBTitle: structure of the vps75-rtt109 histone chaperone-lysine2 acetyltransferase complex (full-length proteins in space group p6122) Phyre2 PDB 2e50 chain A domain 1 Region: 219 - 229 Aligned: 11 Modelled: 11 Confidence: 7.9% Identity: 27% Fold: NAP-like Superfamily: NAP-like Family: NAP-like Phyre2 PDB 1bg1 chain A domain 2 Region: 227 - 235 Aligned: 9 Modelled: 9 Confidence: 7.9% Identity: 56% Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily: p53-like transcription factors Family: STAT DNA-binding domain Phyre2 PDB 3dm7 chain B Region: 219 - 229 Aligned: 11 Modelled: 11 Confidence: 7.7% Identity: 27% PDB header:chaperone Chain: B: PDB Molecule:vacuolar protein sorting-associated protein 75; PDBTitle: crystal structure of the vps75 histone chaperone Phyre2 PDB 5day chain A Region: 219 - 228 Aligned: 10 Modelled: 10 Confidence: 7.6% Identity: 40% PDB header:chaperone Chain: A: PDB Molecule:nap1-related protein 1; PDBTitle: the structure of nap1-related protein(nrp1) in arabidopsis Phyre2 1 c6dmaD_ 2 c2elpA_ 3 c2becB_ 4 d1b8xa1 5 c6hlwB_ 6 d1a6ca3 7 c6hltD_ 8 c1uusA_ 9 c2x3mA_ 10 c6hmvB_ 11 c5o9zN_ 12 c6hs6E_ 13 c1ng7A_ 14 d1ng7a_ 15 c1ljzB_ 16 c3q66A_ 17 d2e50a1 18 d1bg1a2 19 c3dm7B_ 20 c5dayA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34