1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	S	T	R	Y	S	V	A	V	S	A	Q	P	E	T	G	Q	I	A	G	R	A	R	I	A	N	L	A	N	I	L	T	L	L	R	L	V	M	V	P	V	F	L	L	A	L	F	Y	G	G	G	H	H	S	A	A	R	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?																											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	A	W	A	I	F	A	T	A	C	I	T	D	R	F	D	G	L	L	A	R	N	Y	G	M	A	T	E	F	G	A	F	V	D	P	I	A	D	K	T	L	I	G	S	A	L	I	G	L	S	M	L	G	D	L	P	W	W	V	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	L	I	L	T	R	E	L	G	V	T	V	L	R	L	A	V	I	R	R	G	V	I	P	A	S	W	G	G	K	L	K	T	F	V	Q	A	V	A	I	G	L	F	V	L	P	L	S	G	P	L	H	V	A	A	V	V	V	M	A
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Sequence		A	A	I	L	L	T	V	I	T	G	V	D	Y	V	A	R	A	L	R	D	I	G	G	I	R	Q	T	A	S
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 74%) Beta strand ( 0%) TM helix ( 54%) (View membrane topology prediction)

Rank Aligned region

PDB 6h59 chain B Region: 25 - 208 Aligned: 179 Modelled: 184 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:cdp-diacylglycerol--inositol 3-phosphatidyltransferase; PDBTitle: crystal structure of mycobacterium tuberculosis phosphatidylinositol2 phosphate synthase (pgsa1) with cdp-dag bound Phyre2 PDB 5d92 chain B Region: 30 - 203 Aligned: 168 Modelled: 174 Confidence: 99.9% Identity: 18% PDB header:membrane protein Chain: B: PDB Molecule:af2299 protein,phosphatidylinositol synthase; PDBTitle: structure of a phosphatidylinositolphosphate (pip) synthase from2 renibacterium salmoninarum Phyre2 PDB 4o6m chain A Region: 22 - 199 Aligned: 170 Modelled: 178 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:af2299, a cdp-alcohol phosphotransferase; PDBTitle: structure of af2299, a cdp-alcohol phosphotransferase (cmp-bound) Phyre2 PDB 4mnd chain A Region: 30 - 198 Aligned: 162 Modelled: 169 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:ctp l-myo-inositol-1-phosphate cytidylyltransferase/cdp-l- PDBTitle: crystal structure of archaeoglobus fulgidus ipct-dipps bifunctional2 membrane protein Phyre2 PDB 2voy chain G Region: 84 - 112 Aligned: 29 Modelled: 29 Confidence: 32.5% Identity: 14% PDB header:hydrolase Chain: G: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium atpase 1; PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus Phyre2 PDB 4i0x chain J Region: 72 - 103 Aligned: 32 Modelled: 32 Confidence: 24.8% Identity: 13% PDB header:structural genomics, unknown function Chain: J: PDB Molecule:esat-6-like protein mab_3113; PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex Phyre2 PDB 6mjb chain C Region: 81 - 98 Aligned: 18 Modelled: 18 Confidence: 23.3% Identity: 17% PDB header:cell cycle Chain: C: PDB Molecule:kinetochore-associated protein dsn1; PDBTitle: structure of candida glabrata csm1:dsn1(14-72) complex Phyre2 PDB 2rkh chain A Region: 67 - 107 Aligned: 41 Modelled: 41 Confidence: 21.9% Identity: 17% PDB header:transcription Chain: A: PDB Molecule:putative apha-like transcription factor; PDBTitle: crystal structure of a putative apha-like transcription factor2 (zp_00208345.1) from magnetospirillum magnetotacticum ms-1 at 2.00 a3 resolution Phyre2 PDB 2le7 chain A Region: 78 - 91 Aligned: 14 Modelled: 14 Confidence: 13.4% Identity: 36% PDB header:transport protein Chain: A: PDB Molecule:potassium voltage-gated channel subfamily h member 2; PDBTitle: solution nmr structure of the s4s5 linker of herg potassium channel Phyre2 PDB 2mpn chain B Region: 23 - 75 Aligned: 53 Modelled: 53 Confidence: 8.2% Identity: 8% PDB header:membrane protein Chain: B: PDB Molecule:inner membrane protein ygap; PDBTitle: 3d nmr structure of the transmembrane domain of the full-length inner2 membrane protein ygap from escherichia coli Phyre2 PDB 2mpn chain A Region: 23 - 75 Aligned: 53 Modelled: 53 Confidence: 8.2% Identity: 8% PDB header:membrane protein Chain: A: PDB Molecule:inner membrane protein ygap; PDBTitle: 3d nmr structure of the transmembrane domain of the full-length inner2 membrane protein ygap from escherichia coli Phyre2 PDB 4n3x chain D Region: 71 - 82 Aligned: 11 Modelled: 12 Confidence: 7.0% Identity: 45% PDB header:endocytosis Chain: D: PDB Molecule:rab5 gdp/gtp exchange factor; PDBTitle: crystal structure of rabex-5 cc domain Phyre2 PDB 6mje chain B Region: 82 - 98 Aligned: 17 Modelled: 17 Confidence: 5.9% Identity: 18% PDB header:cell cycle Chain: B: PDB Molecule:dsn1p; PDBTitle: structure of candida glabrata csm1: s. cerevisiae dsn1 complex Phyre2 PDB 6mje chain H Region: 82 - 98 Aligned: 17 Modelled: 17 Confidence: 5.9% Identity: 18% PDB header:cell cycle Chain: H: PDB Molecule:dsn1p; PDBTitle: structure of candida glabrata csm1: s. cerevisiae dsn1 complex Phyre2 PDB 6mje chain F Region: 82 - 98 Aligned: 17 Modelled: 17 Confidence: 5.9% Identity: 18% PDB header:cell cycle Chain: F: PDB Molecule:dsn1p; PDBTitle: structure of candida glabrata csm1: s. cerevisiae dsn1 complex Phyre2 PDB 6mje chain D Region: 82 - 98 Aligned: 17 Modelled: 17 Confidence: 5.9% Identity: 18% PDB header:cell cycle Chain: D: PDB Molecule:dsn1p; PDBTitle: structure of candida glabrata csm1: s. cerevisiae dsn1 complex Phyre2 PDB 2cx6 chain A domain 1 Region: 78 - 101 Aligned: 24 Modelled: 23 Confidence: 5.8% Identity: 17% Fold: Barstar-like Superfamily: Barstar-related Family: Barstar-related Phyre2 PDB 4arp chain B Region: 67 - 96 Aligned: 30 Modelled: 30 Confidence: 5.3% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:pesticin; PDBTitle: structure of the inactive pesticin e178a mutant Phyre2 1 c6h59B_ 2 c5d92B_ 3 c4o6mA_ 4 c4mndA_ 5 c2voyG_ 6 c4i0xJ_ 7 c6mjbC_ 8 c2rkhA_ 9 c2le7A_ 10 c2mpnB_ 11 c2mpnA_ 12 c4n3xD_ 13 c6mjeB_ 14 c6mjeH_ 15 c6mjeF_ 16 c6mjeD_ 17 d2cx6a1 18 c4arpB_