1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	D	G	W	K	T	L	R	F	G	E	V	L	E	L	Q	R	G	H	D	L	P	A	A	S	R	G	S	G	T	V	P	V	I	G	S	F	G	V	T	G	M	H	D	T	A	A	Y	D	G	P	G	V	A	I	G	R	S	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?														?	?	?	?	?				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Sequence		A	A	I	G	T	A	T	F	V	A	G	P	I	W	P	L	D	T	C	L	F	V	R	D	F	K	G	N	D	P	R
Secondary structure
SS confidence
Disorder																												?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 4%) Beta strand ( 44%)

Rank Aligned region

PDB 1ydx chain A domain 2 Region: 1 - 88 Aligned: 88 Modelled: 86 Confidence: 99.6% Identity: 16% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 1ydx chain A Region: 4 - 91 Aligned: 87 Modelled: 87 Confidence: 99.4% Identity: 10% PDB header:dna binding protein Chain: A: PDB Molecule:type i restriction enzyme specificity protein mg438; PDBTitle: crystal structure of type-i restriction-modification system s subunit2 from m. genitalium Phyre2 PDB 1ydx chain A domain 1 Region: 2 - 91 Aligned: 89 Modelled: 89 Confidence: 99.1% Identity: 10% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 1yf2 chain A Region: 1 - 90 Aligned: 89 Modelled: 89 Confidence: 98.8% Identity: 13% PDB header:hydrolase regulator Chain: A: PDB Molecule:type i restriction-modification enzyme, s subunit; PDBTitle: three-dimensional structure of dna sequence specificity (s) subunit of2 a type i restriction-modification enzyme and its functional3 implications Phyre2 PDB 3okg chain B Region: 1 - 91 Aligned: 90 Modelled: 91 Confidence: 98.8% Identity: 18% PDB header:dna binding protein Chain: B: PDB Molecule:restriction endonuclease s subunits; PDBTitle: crystal structure of hsds subunit from thermoanaerobacter2 tengcongensis Phyre2 PDB 1yf2 chain A domain 2 Region: 1 - 91 Aligned: 90 Modelled: 91 Confidence: 98.7% Identity: 10% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 2y7c chain A Region: 1 - 91 Aligned: 91 Modelled: 90 Confidence: 98.7% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:type-1 restriction enzyme ecoki specificity protein; PDBTitle: atomic model of the ocr-bound methylase complex from the type i2 restriction-modification enzyme ecoki (m2s1). based on fitting into3 em map 1534. Phyre2 PDB 1yf2 chain A domain 1 Region: 1 - 88 Aligned: 87 Modelled: 87 Confidence: 98.1% Identity: 16% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 3bma chain C Region: 18 - 60 Aligned: 43 Modelled: 43 Confidence: 20.5% Identity: 16% PDB header:ligase Chain: C: PDB Molecule:d-alanyl-lipoteichoic acid synthetase; PDBTitle: crystal structure of d-alanyl-lipoteichoic acid synthetase from2 streptococcus pneumoniae r6 Phyre2 PDB 6pfx chain B Region: 18 - 60 Aligned: 43 Modelled: 43 Confidence: 20.3% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:d-alanyl transferase dltd; PDBTitle: d-alanyl transferase dltd from enterococcus faecium Phyre2 PDB 5uc0 chain B Region: 42 - 74 Aligned: 33 Modelled: 33 Confidence: 17.3% Identity: 33% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein cog5400; PDBTitle: crystal structure of beta-barrel-like, uncharacterized protein of2 cog5400 from brucella abortus Phyre2 PDB 2ysh chain A Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 10.6% Identity: 22% PDB header:protein binding Chain: A: PDB Molecule:growth-arrest-specific protein 7; PDBTitle: solution structure of the ww domain from the human growth-2 arrest-specific protein 7, gas-7 Phyre2 PDB 2f21 chain A domain 1 Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 10.1% Identity: 22% Fold: WW domain-like Superfamily: WW domain Family: WW domain Phyre2 PDB 2lb0 chain A Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 10.1% Identity: 11% PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a di-2 phosphorylated human smad1 derived peptide Phyre2 PDB 2laz chain A Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 10.1% Identity: 11% PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide Phyre2 PDB 1e0m chain A Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 9.8% Identity: 22% PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain Phyre2 PDB 1k9r chain A Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 9.5% Identity: 22% Fold: WW domain-like Superfamily: WW domain Family: WW domain Phyre2 PDB 2jmf chain A domain 1 Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 9.4% Identity: 22% Fold: WW domain-like Superfamily: WW domain Family: WW domain Phyre2 PDB 2lrf chain A Region: 68 - 75 Aligned: 8 Modelled: 8 Confidence: 9.1% Identity: 25% PDB header:antimicrobial protein Chain: A: PDB Molecule:anti-lipopolysaccharide factor; PDBTitle: nmr structure of the scylla serrata anti lipopolysaccharide factor-242 (ssalf-24) peptide Phyre2 PDB 2mdl chain A Region: 68 - 75 Aligned: 8 Modelled: 8 Confidence: 9.1% Identity: 25% PDB header:antimicrobial protein Chain: A: PDB Molecule:anti-lipopolysaccharide factor; PDBTitle: structure and nmr assignments of scylla serrata anti2 lipopolysaccharide factor-24 (ssalf-24) Phyre2 1 d1ydxa2 2 c1ydxA_ 3 d1ydxa1 4 c1yf2A_ 5 c3okgB_ 6 d1yf2a2 7 c2y7cA_ 8 d1yf2a1 9 c3bmaC_ 10 c6pfxB_ 11 c5uc0B_ 12 c2yshA_ 13 d2f21a1 14 c2lb0A_ 15 c2lazA_ 16 c1e0mA_ 17 d1k9ra_ 18 d2jmfa1 19 c2lrfA_ 20 c2mdlA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51