1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	V	E	V	H	S	A	P	G	W	R	A	G	S	S	P	L	G	Y	A	Q	L	Y	L	P	T	R	D	V	Y	W	G	D	M	S	G	I	Y	V	N	A	V	A	T	F	S	E	G	A	A	M	V	S	V	D	D	R	A	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?					?	?																																							?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	P	H	S	S	E	S	R	A	A	D	H	E	R	L	V	L	E	P	R	D	V	E	F	D	W	T	N	L	P	F	H	Y	V	P	N	E	P	M	A	T	H	V	L	N	V	L	H	M	L	L	P	A	G	E	E	F	F	V	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	F	K	K	T	L	P	L	I	K	D	D	Q	L	R	L	D	V	Q	G	F	I	G	Q	E	A	M	H	S	Q	A	H	S	G	V	V	D	H	F	D	A	Q	G	V	D	V	T	A	F	T	N	Q	I	R	W	L	F	E	K	L
Secondary structure
SS confidence
Disorder											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	G	E	S	P	R	R	S	P	R	R	Q	Y	S	W	L	L	E	Q	V	S	F	I	A	A	I	E	H	Y	T	A	V	M	G	E	W	I	L	N	S	P	Q	L	D	A	V	G	A	D	P	V	M	L	D	M	L	R	W	H	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?																														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	E	E	V	E	H	K	A	V	A	F	D	T	M	K	H	L	R	A	G	Y	W	R	Q	V	R	A	Q	L	T	V	T	P	V	M	L	L	L	W	I	R	G	V	R	F	M	Y	S	V	D	P	Y	L	P	P	G	T	K	P	R
Secondary structure
SS confidence
Disorder																																																				?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Sequence		W	R	D	Y	F	K	A	A	R	R	G	L	V	P	G	L	P	R	L	L	R	V	V	G	H	Y	Y	K	P	G	F	H	P	S	Q	L	G	G	L	G	A	A	V	D	Y	L	A	V	S	P	A	A	R	A	S	H
Secondary structure
SS confidence
Disorder											?	?																						?	?	?	?														?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 63%) Beta strand ( 1%) TM helix ( 16%) (View membrane topology prediction)

Rank Aligned region

PDB 1rcw chain A Region: 116 - 282 Aligned: 161 Modelled: 167 Confidence: 95.8% Identity: 11% Fold: Heme oxygenase-like Superfamily: Heme oxygenase-like Family: PqqC-like Phyre2 PDB 3cht chain A Region: 99 - 281 Aligned: 172 Modelled: 183 Confidence: 95.5% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:p-aminobenzoate n-oxygenase; PDBTitle: crystal structure of di-iron aurf with partially bound ligand Phyre2 PDB 5hyh chain A Region: 99 - 280 Aligned: 168 Modelled: 182 Confidence: 93.4% Identity: 16% PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: cmli (chemically reduced state), arylamine oxygenase of2 chloramphenicol biosynthetic pathway Phyre2 PDB 2fzf chain A domain 1 Region: 113 - 257 Aligned: 132 Modelled: 132 Confidence: 90.6% Identity: 12% Fold: Ferritin-like Superfamily: Ferritin-like Family: Ferritin Phyre2 PDB 5olk chain D Region: 92 - 257 Aligned: 164 Modelled: 166 Confidence: 79.0% Identity: 12% PDB header:oxidoreductase Chain: D: PDB Molecule:ribonucleoside-diphosphate reductase, beta subunit 1; PDBTitle: crystal structure of the atp-cone-containing nrdb from2 leeuwenhoekiella blandensis Phyre2 PDB 2o1z chain A Region: 92 - 257 Aligned: 153 Modelled: 166 Confidence: 78.7% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleotide reductase subunit r2; PDBTitle: plasmodium vivax ribonucleotide reductase subunit r2 (pv086155) Phyre2 PDB 3ogh chain B Region: 113 - 264 Aligned: 130 Modelled: 127 Confidence: 72.5% Identity: 8% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ycie; PDBTitle: crystal structure of ycie protein from e. coli cft073, a member of2 ferritine-like superfamily of diiron-containing four-helix-bundle3 proteins Phyre2 PDB 4a58 chain B Region: 92 - 259 Aligned: 145 Modelled: 148 Confidence: 61.6% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:ribonucleoside-diphosphate reductase small chain; PDBTitle: crystal structure of a monometal state of the2 ribonucleotide-reductase small subunit from epstein-barr virus in3 orthorhombic space group Phyre2 PDB 2rcc chain C Region: 83 - 257 Aligned: 173 Modelled: 175 Confidence: 61.3% Identity: 12% PDB header:oxidoreductase Chain: C: PDB Molecule:ribonucleoside-diphosphate reductase subunit beta; PDBTitle: crystal structure of putative class i ribonucleotide reductase2 (np_241368.1) from bacillus halodurans at 1.90 a resolution Phyre2 PDB 2fkz chain A domain 1 Region: 113 - 246 Aligned: 115 Modelled: 118 Confidence: 61.1% Identity: 8% Fold: Ferritin-like Superfamily: Ferritin-like Family: Ferritin Phyre2 PDB 2vux chain B Region: 83 - 257 Aligned: 149 Modelled: 156 Confidence: 58.5% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:ribonucleoside-diphosphate reductase subunit m2 b; PDBTitle: human ribonucleotide reductase, subunit m2 b Phyre2 PDB 2edf chain A Region: 25 - 65 Aligned: 39 Modelled: 41 Confidence: 46.9% Identity: 31% PDB header:contractile protein Chain: A: PDB Molecule:obscurin; PDBTitle: solution structure of the second ig-like domain(2826-2915)2 from human obscurin Phyre2 PDB 1nf4 chain A Region: 101 - 248 Aligned: 127 Modelled: 132 Confidence: 44.6% Identity: 14% Fold: Ferritin-like Superfamily: Ferritin-like Family: Ferritin Phyre2 PDB 2bmo chain B domain 1 Region: 114 - 146 Aligned: 27 Modelled: 33 Confidence: 42.5% Identity: 30% Fold: Cystatin-like Superfamily: NTF2-like Family: Ring hydroxylating beta subunit Phyre2 PDB 3bkn chain B Region: 94 - 246 Aligned: 129 Modelled: 134 Confidence: 41.0% Identity: 20% PDB header:metal binding protein Chain: B: PDB Molecule:bacterioferritin; PDBTitle: the structure of mycobacterial bacterioferritin Phyre2 PDB 6cwq chain A Region: 83 - 257 Aligned: 170 Modelled: 175 Confidence: 40.3% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleotide reductase; PDBTitle: x-ray crystal structure of flavobacterium johnsoniae dimanganese(ii)2 ribonucleotide reductase beta subunit (as-isolated) Phyre2 PDB 5uxg chain B Region: 82 - 246 Aligned: 147 Modelled: 165 Confidence: 40.2% Identity: 14% PDB header:lyase Chain: B: PDB Molecule:aldehyde deformylating oxygenase; PDBTitle: protein 84 with aldehyde deformylating oxygenase activity from2 sulfolobus tokodaii (monoclinic) Phyre2 PDB 4am4 chain B Region: 113 - 246 Aligned: 115 Modelled: 118 Confidence: 38.5% Identity: 11% PDB header:metal binding protein Chain: B: PDB Molecule:bacterioferritin; PDBTitle: bacterioferritin from blastochloris viridis Phyre2 PDB 2htn chain A domain 1 Region: 94 - 246 Aligned: 129 Modelled: 137 Confidence: 37.2% Identity: 15% Fold: Ferritin-like Superfamily: Ferritin-like Family: Ferritin Phyre2 PDB 2vzb chain A Region: 113 - 257 Aligned: 133 Modelled: 145 Confidence: 35.6% Identity: 16% PDB header:metal transport Chain: A: PDB Molecule:putative bacterioferritin-related protein; PDBTitle: a dodecameric thioferritin in the bacterial domain, characterization2 of the bacterioferritin-related protein from bacteroides fragilis Phyre2 1 d1rcwa_ 2 c3chtA_ 3 c5hyhA_ 4 d2fzfa1 5 c5olkD_ 6 c2o1zA_ 7 c3oghB_ 8 c4a58B_ 9 c2rccC_ 10 d2fkza1 11 c2vuxB_ 12 c2edfA_ 13 d1nf4a_ 14 d2bmob1 15 c3bknB_ 16 c6cwqA_ 17 c5uxgB_ 18 c4am4B_ 19 d2htna1 20 c2vzbA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99