1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	R	R	R	L	A	I	V	Q	R	W	R	G	Q	D	E	I	P	T	D	W	G	R	C	V	L	T	I	G	V	F	D	G	V	H	R	G	H	A	E	L	I	A	H	A	V	K	A	G	R	A	R	G	V	P	A	V	L	M	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	D	P	H	P	M	E	V	V	Y	P	G	S	H	P	A	Q	L	T	T	L	T	R	R	A	E	L	V	Q	D	L	G	I	E	V	F	L	V	M	P	F	T	T	D	F	M	K	L	T	P	D	R	F	I	H	E	L	L	V	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	L	H	V	V	E	V	V	V	G	E	N	F	T	F	G	K	K	A	A	G	N	V	D	T	L	R	R	A	G	E	R	F	G	F	A	V	E	S	M	S	L	V	S	E	H	H	S	N	E	T	V	T	F	S	S	T	Y	I	R
Secondary structure
SS confidence
Disorder																																																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	C	V	D	A	G	D	M	V	A	A	M	E	A	L	G	R	P	H	R	V	E	G	V	V	V	R	G	E	G	R	G	A	E	L	G	F	P	T	A	N	V	A	P	P	M	Y	S	A	I	P	A	D	G	V	Y	A	A	W	F
Secondary structure
SS confidence
Disorder																																															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	V	L	G	H	G	P	V	T	G	T	V	V	P	G	E	R	Y	Q	A	A	V	S	V	G	T	N	P	T	F	S	G	R	T	R	T	V	E	A	F	V	L	D	T	T	A	D	L	Y	G	Q	H	V	A	L	D	F	V	G	R
Secondary structure
SS confidence
Disorder								?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.
Sequence		I	R	G	Q	K	K	F	E	S	V	R	Q	L	V	A	A	M	G	A	D	T	E	R	A	R	D	L	L	S	T	G
Secondary structure
SS confidence
Disorder							?		?																						?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 32%) Beta strand ( 27%)

Rank Aligned region

PDB 2x0k chain B Region: 8 - 329 Aligned: 317 Modelled: 322 Confidence: 100.0% Identity: 45% PDB header:transferase Chain: B: PDB Molecule:riboflavin biosynthesis protein ribf; PDBTitle: crystal structure of modular fad synthetase from2 corynebacterium ammoniagenes Phyre2 PDB 3op1 chain A Region: 7 - 327 Aligned: 292 Modelled: 321 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:macrolide-efflux protein; PDBTitle: crystal structure of macrolide-efflux protein sp_1110 from2 streptococcus pneumoniae Phyre2 PDB 1t6z chain B Region: 25 - 329 Aligned: 261 Modelled: 305 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: B: PDB Molecule:riboflavin kinase/fmn adenylyltransferase; PDBTitle: crystal structure of riboflavin bound tm379 Phyre2 PDB 1nb9 chain A Region: 197 - 330 Aligned: 124 Modelled: 134 Confidence: 100.0% Identity: 34% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin kinase-like Family: ATP-dependent riboflavin kinase-like Phyre2 PDB 1n08 chain A Region: 197 - 329 Aligned: 122 Modelled: 133 Confidence: 100.0% Identity: 30% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin kinase-like Family: ATP-dependent riboflavin kinase-like Phyre2 PDB 3bnw chain A Region: 197 - 330 Aligned: 118 Modelled: 134 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:riboflavin kinase, putative; PDBTitle: crystal structure of riboflavin kinase from trypanosoma brucei Phyre2 PDB 1mrz chain A domain 1 Region: 198 - 329 Aligned: 102 Modelled: 132 Confidence: 100.0% Identity: 35% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin kinase-like Family: ATP-dependent riboflavin kinase-like Phyre2 PDB 1mrz chain A domain 2 Region: 25 - 197 Aligned: 157 Modelled: 173 Confidence: 100.0% Identity: 33% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 5xf2 chain B Region: 15 - 187 Aligned: 143 Modelled: 168 Confidence: 99.9% Identity: 22% PDB header:transferase Chain: B: PDB Molecule:putative cytidylyltransferase; PDBTitle: crystal structure of semet-hldc from burkholderia pseudomallei Phyre2 PDB 3guz chain B Region: 5 - 163 Aligned: 150 Modelled: 159 Confidence: 99.9% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's Phyre2 PDB 5x3d chain A Region: 22 - 161 Aligned: 120 Modelled: 135 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate phosphomutase; PDBTitle: crystal structure of hep-cmp-bound form of cytidylyltransferase2 (cytase) domain of fom1 from streptomyces wedmorensis Phyre2 PDB 4zcs chain E Region: 21 - 185 Aligned: 137 Modelled: 165 Confidence: 99.8% Identity: 17% PDB header:transferase Chain: E: PDB Molecule:choline-phosphate cytidylyltransferase; PDBTitle: crystal structure of the c-terminal catalytic domain of plasmodium2 falciparum ctp:phosphocholine cytidylyltransferase in complex with3 cdp-choline Phyre2 PDB 3glv chain B Region: 23 - 162 Aligned: 116 Modelled: 140 Confidence: 99.8% Identity: 19% PDB header:biosynthetic protein Chain: B: PDB Molecule:lipopolysaccharide core biosynthesis protein; PDBTitle: crystal structure of the lipopolysaccharide core biosynthesis protein2 from thermoplasma volcanium gss1 Phyre2 PDB 1coz chain A Region: 23 - 183 Aligned: 125 Modelled: 161 Confidence: 99.7% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Cytidylyltransferase Phyre2 PDB 1lw7 chain A Region: 21 - 208 Aligned: 177 Modelled: 188 Confidence: 99.7% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:transcriptional regulator nadr; PDBTitle: nadr protein from haemophilus influenzae Phyre2 PDB 3h05 chain A Region: 22 - 187 Aligned: 137 Modelled: 166 Confidence: 99.6% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein vpa0413; PDBTitle: the crystal structure of a putative nicotinate-nucleotide2 adenylyltransferase from vibrio parahaemolyticus Phyre2 PDB 3uk2 chain B Region: 4 - 176 Aligned: 164 Modelled: 173 Confidence: 99.6% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: the structure of pantothenate synthetase from burkholderia2 thailandensis Phyre2 PDB 1lw7 chain A domain 1 Region: 22 - 185 Aligned: 155 Modelled: 164 Confidence: 99.6% Identity: 14% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 1v8f chain A Region: 5 - 176 Aligned: 159 Modelled: 172 Confidence: 99.6% Identity: 23% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) Phyre2 PDB 2h29 chain A Region: 22 - 187 Aligned: 158 Modelled: 166 Confidence: 99.6% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide PDBTitle: crystal structure of nicotinic acid mononucleotide2 adenylyltransferase from staphylococcus aureus: product3 bound form 1 Phyre2 1 c2x0kB_ 2 c3op1A_ 3 c1t6zB_ 4 d1nb9a_ 5 d1n08a_ 6 c3bnwA_ 7 d1mrza1 8 d1mrza2 9 c5xf2B_ 10 c3guzB_ 11 c5x3dA_ 12 c4zcsE_ 13 c3glvB_ 14 d1coza_ 15 c1lw7A_ 16 c3h05A_ 17 c3uk2B_ 18 d1lw7a1 19 d1v8fa_ 20 c2h29A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172