1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	K	L	S	V	S	L	S	D	D	D	V	A	I	L	D	A	Y	V	K	R	A	G	L	P	S	R	S	A	G	L	Q	H	A	I	R	V	L	R	Y	P	T	L	E	D	D	Y	A	N	A	W	Q	E	W	S	A	A	G	D	T
Secondary structure
SS confidence
Disorder		?	?				?	?															?				?													?															?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.
Sequence		D	A	W	E	Q	T	V	G	D	G	V	G	D	A	P	R
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 74%) Beta strand ( 7%)

Rank Aligned region

PDB 2bj7 chain A domain 1 Region: 1 - 38 Aligned: 38 Modelled: 38 Confidence: 97.7% Identity: 21% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 2bj3 chain D Region: 1 - 38 Aligned: 38 Modelled: 38 Confidence: 97.6% Identity: 21% PDB header:transcription Chain: D: PDB Molecule:nickel responsive regulator; PDBTitle: nikr-apo Phyre2 PDB 2hza chain A domain 1 Region: 2 - 36 Aligned: 35 Modelled: 35 Confidence: 97.5% Identity: 29% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 1q5v chain B Region: 1 - 38 Aligned: 38 Modelled: 38 Confidence: 97.5% Identity: 26% PDB header:transcription Chain: B: PDB Molecule:nickel responsive regulator; PDBTitle: apo-nikr Phyre2 PDB 2hza chain B domain 1 Region: 2 - 36 Aligned: 35 Modelled: 35 Confidence: 97.4% Identity: 29% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 2ca9 chain B Region: 1 - 38 Aligned: 38 Modelled: 38 Confidence: 97.4% Identity: 32% PDB header:transcription Chain: B: PDB Molecule:putative nickel-responsive regulator; PDBTitle: apo-nikr from helicobacter pylori in closed trans-2 conformation Phyre2 PDB 5ceg chain C Region: 2 - 64 Aligned: 63 Modelled: 63 Confidence: 94.5% Identity: 19% PDB header:toxin Chain: C: PDB Molecule:addiction module antidote protein, copg/arc/metj family; PDBTitle: x-ray structure of toxin/anti-toxin complex from mesorhizobium2 opportunistum Phyre2 PDB 5yrz chain C Region: 1 - 36 Aligned: 31 Modelled: 36 Confidence: 93.8% Identity: 26% PDB header:antitoxin/hydrolase Chain: C: PDB Molecule:hicb; PDBTitle: toxin-antitoxin complex from streptococcus pneumoniae Phyre2 PDB 3kxe chain D Region: 3 - 65 Aligned: 63 Modelled: 63 Confidence: 93.3% Identity: 22% PDB header:protein binding Chain: D: PDB Molecule:antitoxin protein pard-1; PDBTitle: a conserved mode of protein recognition and binding in a2 pard-pare toxin-antitoxin complex Phyre2 PDB 6g1n chain B Region: 1 - 36 Aligned: 35 Modelled: 36 Confidence: 92.4% Identity: 29% PDB header:antitoxin Chain: B: PDB Molecule:antitoxin hicb; PDBTitle: crystal structure of the burkholderia pseudomallei antitoxin hicb Phyre2 PDB 2k5j chain B Region: 1 - 36 Aligned: 35 Modelled: 36 Confidence: 88.4% Identity: 23% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 Phyre2 PDB 4me7 chain E Region: 2 - 37 Aligned: 35 Modelled: 34 Confidence: 82.1% Identity: 31% PDB header:hydrolase/hydrolase inhibitor Chain: E: PDB Molecule:antitoxin endoai; PDBTitle: crystal structure of bacillus subtilis toxin mazf in complex with2 cognate antitoxin maze Phyre2 PDB 4p7d chain A Region: 1 - 36 Aligned: 36 Modelled: 36 Confidence: 78.0% Identity: 25% PDB header:toxin Chain: A: PDB Molecule:antitoxin hicb3; PDBTitle: antitoxin hicb3 crystal structure Phyre2 PDB 6a6x chain C Region: 13 - 71 Aligned: 47 Modelled: 59 Confidence: 55.0% Identity: 30% PDB header:toxin Chain: C: PDB Molecule:antitoxin maze7; PDBTitle: the crystal structure of the mtb maze-mazf-mt9 complex Phyre2 PDB 2cpg chain A Region: 2 - 35 Aligned: 33 Modelled: 34 Confidence: 51.9% Identity: 30% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 1ea4 chain K Region: 2 - 35 Aligned: 33 Modelled: 34 Confidence: 51.9% Identity: 30% PDB header:gene regulation/dna Chain: K: PDB Molecule:transcriptional repressor copg; PDBTitle: transcriptional repressor copg/22bp dsdna complex Phyre2 PDB 6qeq chain D Region: 1 - 35 Aligned: 35 Modelled: 35 Confidence: 51.6% Identity: 14% PDB header:dna binding protein Chain: D: PDB Molecule:pcff; PDBTitle: pcff from enterococcus faecalis pcf10 Phyre2 PDB 2mdv chain B Region: 3 - 36 Aligned: 33 Modelled: 34 Confidence: 27.1% Identity: 33% PDB header:de novo protein Chain: B: PDB Molecule:designed protein; PDBTitle: nmr structure of beta alpha alpha 38 Phyre2 PDB 2vy4 chain A domain 1 Region: 18 - 39 Aligned: 22 Modelled: 22 Confidence: 21.2% Identity: 27% Fold: beta-beta-alpha zinc fingers Superfamily: beta-beta-alpha zinc fingers Family: CHHC finger Phyre2 PDB 5cww chain C Region: 24 - 41 Aligned: 18 Modelled: 18 Confidence: 16.0% Identity: 33% PDB header:transport protein Chain: C: PDB Molecule:nucleoporin nup159; PDBTitle: crystal structure of the chaetomium thermophilum heterotrimeric nup822 ntd-nup159 tail-nup145n apd complex Phyre2 1 d2bj7a1 2 c2bj3D_ 3 d2hzaa1 4 c1q5vB_ 5 d2hzab1 6 c2ca9B_ 7 c5cegC_ 8 c5yrzC_ 9 c3kxeD_ 10 c6g1nB_ 11 c2k5jB_ 12 c4me7E_ 13 c4p7dA_ 14 c6a6xC_ 15 d2cpga_ 16 c1ea4K_ 17 c6qeqD_ 18 c2mdvB_ 19 d2vy4a1 20 c5cwwC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65