1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	C	P	S	L	V	G	L	R	T	E	A	A	E	L	S	Y	S	D	Q	P	D	A	L	G	V	A	M	R	E	R	R	E	Q	Q	N	L	V	R	P	P	R	R	N	A	S	R	R	I	N	T	D	Q	T	S	T	K	Y	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?			?					?		?		?																	?	?	?	?	?	?	?											?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	I	T	Y	M	P	E	T	L	T	G	R	L	N	F	R	L	S	P	E	Q	E	Q	A	L	R	H	A	A	A	L	T	G	Q	S	L	S	G	F	V	L	S	A	A	V	D	H	A	H	D	L	L	A	R	A	N	R	I	E	L
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Sequence		S	E	A	A	F	R	R	F	V	A	A	L	D	E	P	D	E	A	A	P	E	L	V	R	L	A	R	R	K	S	R	I	P	P	H
Secondary structure
SS confidence
Disorder																		?	?									?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 29%) Alpha helix ( 75%) Beta strand ( 1%)

Rank Aligned region

PDB 6gts chain C Region: 69 - 150 Aligned: 82 Modelled: 82 Confidence: 99.9% Identity: 29% PDB header:transcription Chain: C: PDB Molecule:duf1778 domain-containing protein; PDBTitle: structure of the atat-atar complex bound dna Phyre2 PDB 1y9b chain A domain 1 Region: 68 - 147 Aligned: 80 Modelled: 80 Confidence: 99.9% Identity: 31% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: VCA0319-like Phyre2 PDB 6ajn chain F Region: 71 - 135 Aligned: 65 Modelled: 65 Confidence: 99.8% Identity: 31% PDB header:toxin Chain: F: PDB Molecule:duf1778 domain-containing protein; PDBTitle: crystal structure of atatr bound with accoa Phyre2 PDB 6gtr chain D Region: 115 - 148 Aligned: 34 Modelled: 34 Confidence: 97.5% Identity: 32% PDB header:transcription Chain: D: PDB Molecule:duf1778 domain-containing protein; PDBTitle: structure of the atat y144f mutant toxin bound to the c-terminus of2 the antitoxin atar and acetyl-coa Phyre2 PDB 6qeq chain D Region: 69 - 106 Aligned: 38 Modelled: 38 Confidence: 95.7% Identity: 16% PDB header:dna binding protein Chain: D: PDB Molecule:pcff; PDBTitle: pcff from enterococcus faecalis pcf10 Phyre2 PDB 6g1n chain B Region: 2 - 107 Aligned: 106 Modelled: 106 Confidence: 95.4% Identity: 13% PDB header:antitoxin Chain: B: PDB Molecule:antitoxin hicb; PDBTitle: crystal structure of the burkholderia pseudomallei antitoxin hicb Phyre2 PDB 4p7d chain A Region: 2 - 107 Aligned: 106 Modelled: 106 Confidence: 94.5% Identity: 15% PDB header:toxin Chain: A: PDB Molecule:antitoxin hicb3; PDBTitle: antitoxin hicb3 crystal structure Phyre2 PDB 2an7 chain A Region: 71 - 102 Aligned: 32 Modelled: 32 Confidence: 90.6% Identity: 31% PDB header:dna binding protein Chain: A: PDB Molecule:protein pard; PDBTitle: solution structure of the bacterial antidote pard Phyre2 PDB 2ba3 chain A Region: 69 - 105 Aligned: 37 Modelled: 37 Confidence: 84.4% Identity: 27% PDB header:dna binding protein Chain: A: PDB Molecule:nika; PDBTitle: nmr structure of nika n-terminal fragment Phyre2 PDB 1mnt chain A Region: 72 - 107 Aligned: 36 Modelled: 36 Confidence: 81.4% Identity: 28% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 1u9p chain A Region: 69 - 143 Aligned: 72 Modelled: 75 Confidence: 79.6% Identity: 11% PDB header:unknown function Chain: A: PDB Molecule:parc; PDBTitle: permuted single-chain arc Phyre2 PDB 4mx6 chain A Region: 76 - 132 Aligned: 57 Modelled: 57 Confidence: 77.2% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:trap-type c4-dicarboxylate:h+ symport system substrate- PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 shewanella oneidensis (so_3134), target efi-510275, with bound3 succinate Phyre2 PDB 4nap chain D Region: 76 - 131 Aligned: 56 Modelled: 54 Confidence: 76.7% Identity: 20% PDB header:transport protein Chain: D: PDB Molecule:extracellular solute-binding protein, family 7; PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 desulfovibrio alaskensis g20 (dde_0634), target efi-510102, with3 bound d-tryptophan Phyre2 PDB 3qoq chain C Region: 66 - 107 Aligned: 42 Modelled: 42 Confidence: 75.1% Identity: 10% PDB header:transcription/dna Chain: C: PDB Molecule:alginate and motility regulator z; PDBTitle: crystal structure of the transcription factor amrz in complex with the2 18 base pair amrz1 binding site Phyre2 PDB 2k29 chain A Region: 71 - 110 Aligned: 40 Modelled: 40 Confidence: 74.6% Identity: 20% PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb Phyre2 PDB 1b28 chain A Region: 72 - 106 Aligned: 35 Modelled: 35 Confidence: 71.0% Identity: 20% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 4pfi chain A Region: 76 - 132 Aligned: 57 Modelled: 57 Confidence: 69.5% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:trap dicarboxylate transporter-dctp subunit; PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 marinobacter aquaeolei vt8 (maqu_2829, target efi-510133), apo open3 structure Phyre2 PDB 2bj7 chain A domain 1 Region: 72 - 107 Aligned: 36 Modelled: 36 Confidence: 68.0% Identity: 11% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 5yrz chain C Region: 64 - 107 Aligned: 40 Modelled: 44 Confidence: 67.9% Identity: 15% PDB header:antitoxin/hydrolase Chain: C: PDB Molecule:hicb; PDBTitle: toxin-antitoxin complex from streptococcus pneumoniae Phyre2 PDB 1myl chain A Region: 69 - 110 Aligned: 42 Modelled: 42 Confidence: 66.7% Identity: 17% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 1 c6gtsC_ 2 d1y9ba1 3 c6ajnF_ 4 c6gtrD_ 5 c6qeqD_ 6 c6g1nB_ 7 c4p7dA_ 8 c2an7A_ 9 c2ba3A_ 10 d1mnta_ 11 c1u9pA_ 12 c4mx6A_ 13 c4napD_ 14 c3qoqC_ 15 c2k29A_ 16 d1b28a_ 17 c4pfiA_ 18 d2bj7a1 19 c5yrzC_ 20 d1myla_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99