1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	V	I	Q	D	D	Y	V	K	Q	A	E	V	I	R	G	L	P	K	K	K	N	G	F	E	L	T	T	T	Q	L	R	V	L	L	S	L	T	A	Q	L	F	D	E	A	Q	Q	S	A	N	P	T	L	P	R	Q	L	K	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?														?	?	?	?																								?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	V	Q	Y	L	R	V	R	F	V	Y	Q	S	G	R	E	D	A	V	K	T	F	V	R	N	A	K	L	L	E	A	L	E	G	I	G	D	S	R	D	G	L	L	R	F	C	R	Y	M	E	A	L	A	A	Y	K	K	Y	L	D
Secondary structure
SS confidence
Disorder																			?																?	?	?	?	?																						?
Disorder confidence
		.	.	.	.
Sequence		P	K	D	K
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 24%) Alpha helix ( 81%) Beta strand ( 0%)

Rank Aligned region

PDB 6ifu chain B Region: 2 - 120 Aligned: 114 Modelled: 119 Confidence: 100.0% Identity: 48% PDB header:rna binding protein Chain: B: PDB Molecule:type iii-a crispr-associated protein csm2; PDBTitle: cryo-em structure of type iii-a csm-ctr2-dsdna complex Phyre2 PDB 6ae1 chain B Region: 11 - 120 Aligned: 110 Modelled: 110 Confidence: 100.0% Identity: 30% PDB header:rna binding protein Chain: B: PDB Molecule:crispr-associated protein, tm1810 family; PDBTitle: crystal structure of csm2 of the type iii-a crispr-cas effector2 complex Phyre2 PDB 5an6 chain A Region: 6 - 119 Aligned: 108 Modelled: 114 Confidence: 100.0% Identity: 24% PDB header:dna binding protein Chain: A: PDB Molecule:crispr-associated protein, csm2 family; PDBTitle: crystal structure of thermotoga maritima csm2 Phyre2 PDB 6mus chain B Region: 5 - 122 Aligned: 110 Modelled: 118 Confidence: 100.0% Identity: 16% PDB header:rna binding protein/rna Chain: B: PDB Molecule:uncharacterized protein csm2; PDBTitle: cryo-em structure of larger csm-crrna-target rna ternary complex in2 type iii-a crispr-cas system Phyre2 PDB 3cr5 chain X domain 1 Region: 30 - 119 Aligned: 87 Modelled: 90 Confidence: 79.1% Identity: 11% Fold: EF Hand-like Superfamily: EF-hand Family: S100 proteins Phyre2 PDB 2rgi chain A Region: 30 - 121 Aligned: 87 Modelled: 89 Confidence: 78.8% Identity: 13% PDB header:metal binding protein Chain: A: PDB Molecule:protein s100-a2; PDBTitle: crystal structure of ca2+-free s100a2 at 1.6 a resolution Phyre2 PDB 1qlk chain A Region: 30 - 122 Aligned: 88 Modelled: 93 Confidence: 75.4% Identity: 16% Fold: EF Hand-like Superfamily: EF-hand Family: S100 proteins Phyre2 PDB 3jq3 chain A Region: 98 - 124 Aligned: 27 Modelled: 27 Confidence: 66.1% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:lombricine kinase; PDBTitle: crystal structure of lombricine kinase, complexed with substrate adp Phyre2 PDB 2kax chain A Region: 29 - 124 Aligned: 90 Modelled: 96 Confidence: 59.9% Identity: 14% PDB header:metal binding protein Chain: A: PDB Molecule:protein s100-a5; PDBTitle: solution structure and dynamics of s100a5 in the apo and2 ca2+ -bound states Phyre2 PDB 5ady chain 6 Region: 10 - 70 Aligned: 60 Modelled: 61 Confidence: 51.8% Identity: 25% PDB header:ribosome Chain: 6: PDB Molecule:gtpase hflx; PDBTitle: cryo-em structures of the 50s ribosome subunit bound with hflx Phyre2 PDB 1zfs chain A domain 1 Region: 30 - 119 Aligned: 85 Modelled: 87 Confidence: 45.1% Identity: 16% Fold: EF Hand-like Superfamily: EF-hand Family: S100 proteins Phyre2 PDB 1qls chain A Region: 29 - 119 Aligned: 86 Modelled: 91 Confidence: 40.2% Identity: 12% Fold: EF Hand-like Superfamily: EF-hand Family: S100 proteins Phyre2 PDB 1kso chain A Region: 59 - 121 Aligned: 61 Modelled: 63 Confidence: 38.6% Identity: 11% Fold: EF Hand-like Superfamily: EF-hand Family: S100 proteins Phyre2 PDB 1q3m chain A Region: 114 - 121 Aligned: 8 Modelled: 8 Confidence: 35.6% Identity: 38% Fold: GLA-domain Superfamily: GLA-domain Family: GLA-domain Phyre2 PDB 1qk1 chain H Region: 98 - 124 Aligned: 27 Modelled: 27 Confidence: 31.9% Identity: 11% PDB header:transferase (creatine kinase) Chain: H: PDB Molecule:creatine kinase, ubiquitous mitochondrial; PDBTitle: crystal structure of human ubiquitous mitochondrial creatine kinase Phyre2 PDB 5hyd chain A Region: 29 - 119 Aligned: 86 Modelled: 88 Confidence: 29.7% Identity: 20% PDB header:protein binding Chain: A: PDB Molecule:protein s100-z; PDBTitle: crystal structure of calcium-free human s100z Phyre2 PDB 1rl9 chain A Region: 98 - 124 Aligned: 27 Modelled: 27 Confidence: 29.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:arginine kinase; PDBTitle: crystal structure of creatine-adp arginine kinase ternary2 complex Phyre2 PDB 1dc1 chain A Region: 69 - 114 Aligned: 46 Modelled: 46 Confidence: 26.4% Identity: 13% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: Restriction endonuclease BsobI Phyre2 PDB 1q8h chain A Region: 114 - 120 Aligned: 7 Modelled: 7 Confidence: 24.2% Identity: 29% Fold: GLA-domain Superfamily: GLA-domain Family: GLA-domain Phyre2 PDB 1q8h chain A Region: 114 - 120 Aligned: 7 Modelled: 7 Confidence: 24.2% Identity: 29% PDB header:metal binding protein Chain: A: PDB Molecule:osteocalcin; PDBTitle: crystal structure of porcine osteocalcin Phyre2 1 c6ifuB_ 2 c6ae1B_ 3 c5an6A_ 4 c6musB_ 5 d3cr5x1 6 c2rgiA_ 7 d1qlka_ 8 c3jq3A_ 9 c2kaxA_ 10 c5ady6_ 11 d1zfsa1 12 d1qlsa_ 13 d1ksoa_ 14 d1q3ma_ 15 c1qk1H_ 16 c5hydA_ 17 c1rl9A_ 18 d1dc1a_ 19 d1q8ha_ 20 c1q8hA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99