1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	S	P	A	G	A	D	R	R	I	P	T	W	A	S	R	V	V	S	G	L	A	R	D	R	P	V	V	V	T	K	E	D	L	T	Q	R	L	T	E	A	G	C	G	R	D	P	D	S	A	I	R	E	L	R	R	I	G	W
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?															?																				?	?		?	?	?											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	V	Q	L	P	V	K	G	T	W	A	F	I	P	P	G	E	A	A	I	S	D	P	Y	L	P	L	R	S	W	L	A	R	D	Q	N	A	G	F	M	L	A	G	A	S	A	A	W	H	L	G	Y	L	D	R	Q	P	D	G	R
Secondary structure
SS confidence
Disorder		?	?																																																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	P	I	W	L	P	P	A	K	R	L	P	D	G	L	A	S	Y	V	S	V	V	R	I	P	W	N	A	A	D	T	A	L	L	A	P	R	P	A	L	L	V	R	R	R	L	D	L	V	A	W	A	T	G	L	P	A	L	G	P
Secondary structure
SS confidence
Disorder																															?	?	?	?				?	?						?	?	?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	A	L	L	V	Q	I	A	T	R	P	A	S	F	G	P	W	A	D	L	V	P	H	L	D	D	L	V	A	D	C	S	D	E	R	L	E	R	L	L	S	G	R	P	T	S	A	W	Q	R	A	S	Y	L	L	D	S	G	G	E
Secondary structure
SS confidence
Disorder										?	?	?	?		?		?																												?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
Sequence		P	A	R	G	Q	A	L	L	A	K	R	H	T	E	V	M	P	V	T	R	F	T	T	A	H	S	R	D	R	G	E	S	V	W	A	P	E	Y	Q	L	V	D	E	L	V	V	P	L	L	R	V	I	G	K	A
Secondary structure
SS confidence
Disorder			?	?	?	?				?											?		?	?	?	?	?	?		?	?	?	?	?																			?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 53%) Beta strand ( 6%)

Rank Aligned region

PDB 1zel chain A Region: 1 - 294 Aligned: 291 Modelled: 294 Confidence: 100.0% Identity: 100% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rv2827c; PDBTitle: crystal structure of rv2827c protein from mycobacterium tuberculosis Phyre2 PDB 1zel chain A domain 2 Region: 83 - 294 Aligned: 209 Modelled: 212 Confidence: 100.0% Identity: 100% Fold: Rv2827c C-terminal domain-like Superfamily: Rv2827c C-terminal domain-like Family: Rv2827c C-terminal domain-like Phyre2 PDB 1zel chain A domain 1 Region: 1 - 82 Aligned: 82 Modelled: 82 Confidence: 100.0% Identity: 100% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Rv2827c N-terminal domain-like Phyre2 PDB 1d8c chain A Region: 40 - 67 Aligned: 28 Modelled: 28 Confidence: 33.6% Identity: 29% Fold: TIM beta/alpha-barrel Superfamily: Malate synthase G Family: Malate synthase G Phyre2 PDB 5es2 chain A Region: 194 - 210 Aligned: 17 Modelled: 17 Confidence: 33.1% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein lpg0634; PDBTitle: the crystal structure of a functionally uncharacterized protein2 lpg0634 from legionella pneumophila subsp. pneumophila str.3 philadelphia 1 Phyre2 PDB 3rnl chain A Region: 199 - 230 Aligned: 30 Modelled: 32 Confidence: 21.8% Identity: 43% PDB header:transferase Chain: A: PDB Molecule:sulfotransferase; PDBTitle: crystal structure of sulfotransferase from alicyclobacillus2 acidocaldarius Phyre2 PDB 5z5m chain B Region: 188 - 224 Aligned: 35 Modelled: 37 Confidence: 20.7% Identity: 20% PDB header:lyase Chain: B: PDB Molecule:predicted protein; PDBTitle: crystal structure of (s)-allantoin synthase Phyre2 PDB 1aoy chain A Region: 31 - 80 Aligned: 50 Modelled: 50 Confidence: 17.7% Identity: 18% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Arginine repressor (ArgR), N-terminal DNA-binding domain Phyre2 PDB 5vmo chain B Region: 51 - 59 Aligned: 9 Modelled: 9 Confidence: 14.2% Identity: 78% PDB header:viral protein/apoptosis Chain: B: PDB Molecule:bcl-2 interacting mediator of cell death; PDBTitle: crystal structure of grouper iridovirus giv66:bim complex Phyre2 PDB 2kzt chain A Region: 197 - 274 Aligned: 74 Modelled: 78 Confidence: 13.7% Identity: 19% PDB header:apoptosis Chain: A: PDB Molecule:programmed cell death protein 4; PDBTitle: structure of the tandem ma-3 region of pdcd4 Phyre2 PDB 1ug7 chain A Region: 192 - 205 Aligned: 14 Modelled: 14 Confidence: 10.4% Identity: 43% Fold: Four-helical up-and-down bundle Superfamily: Domain from hypothetical 2610208m17rik protein Family: Domain from hypothetical 2610208m17rik protein Phyre2 PDB 1ati chain A Region: 46 - 76 Aligned: 31 Modelled: 31 Confidence: 9.8% Identity: 23% PDB header:protein biosynthesis Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus Phyre2 PDB 5ool chain D Region: 47 - 92 Aligned: 45 Modelled: 46 Confidence: 9.8% Identity: 27% PDB header:ribosome Chain: D: PDB Molecule:39s ribosomal protein l2, mitochondrial; PDBTitle: structure of a native assembly intermediate of the human mitochondrial2 ribosome with unfolded interfacial rrna Phyre2 PDB 1ggm chain B Region: 46 - 76 Aligned: 31 Modelled: 31 Confidence: 9.3% Identity: 23% PDB header:ligase Chain: B: PDB Molecule:glycine--trna ligase; PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate Phyre2 PDB 3qd7 chain X Region: 42 - 88 Aligned: 47 Modelled: 47 Confidence: 8.6% Identity: 17% PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized protein ydal; PDBTitle: crystal structure of ydal, a stand-alone small muts-related protein2 from escherichia coli Phyre2 PDB 4rhz chain A Region: 122 - 148 Aligned: 27 Modelled: 27 Confidence: 8.5% Identity: 15% PDB header:toxin Chain: A: PDB Molecule:cry23aa1; PDBTitle: crystal structure of cry23aa1 and cry37aa1 binary protein complex Phyre2 PDB 2bcw chain C Region: 202 - 227 Aligned: 26 Modelled: 26 Confidence: 8.3% Identity: 19% PDB header:ribosome Chain: C: PDB Molecule:elongation factor g; PDBTitle: coordinates of the n-terminal domain of ribosomal protein l11,c-2 terminal domain of ribosomal protein l7/l12 and a portion of the g'3 domain of elongation factor g, as fitted into cryo-em map of an4 escherichia coli 70s*ef-g*gdp*fusidic acid complex Phyre2 PDB 4wqk chain A Region: 173 - 219 Aligned: 47 Modelled: 47 Confidence: 7.6% Identity: 6% PDB header:transferase Chain: A: PDB Molecule:2''-aminoglycoside nucleotidyltransferase; PDBTitle: crystal structure of aminoglycoside nucleotidylyltransferase ant(2")-2 ia, apo form Phyre2 PDB 5zz5 chain D Region: 25 - 74 Aligned: 48 Modelled: 50 Confidence: 7.6% Identity: 23% PDB header:gene regulation Chain: D: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: redox-sensing transcriptional repressor rex Phyre2 PDB 1bqf chain A Region: 96 - 120 Aligned: 11 Modelled: 11 Confidence: 7.0% Identity: 73% PDB header:hormone/growth factor Chain: A: PDB Molecule:protein (growth-blocking peptide); PDBTitle: growth-blocking peptide (gbp) from pseudaletia separata Phyre2 1 c1zelA_ 2 d1zela2 3 d1zela1 4 d1d8ca_ 5 c5es2A_ 6 c3rnlA_ 7 c5z5mB_ 8 d1aoya_ 9 c5vmoB_ 10 c2kztA_ 11 d1ug7a_ 12 c1atiA_ 13 c5oold_ 14 c1ggmB_ 15 c3qd7X_ 16 c4rhzA_ 17 c2bcwC_ 18 c4wqkA_ 19 c5zz5D_ 20 c1bqfA_ 21 22 23 24 25 26 27 28 29 30 31 32 33