1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	A	P	Q	R	A	R	L	R	S	S	K	E	R	V	R	D	Y	A	L	F	V	V	L	V	G	P	N	V	A	L	L	L	L	F	V	Y	R	P	L	A	D	N	I	R	L	S	F	F	D	W	N	V	S	D	P	S	A	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																																					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	V	G	L	S	N	Y	T	E	W	F	T	R	S	D	T	R	Q	I	V	F	N	T	A	V	F	T	G	A	A	V	V	G	S	M	V	L	G	L	A	L	A	M	L	L	D	R	P	L	R	G	R	N	L	V	R	S	T	V	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	P	F	V	I	S	G	A	A	V	G	L	A	A	Q	F	V	F	D	P	H	F	G	L	I	Q	D	L	L	R	R	I	G	V	G	V	P	D	F	Y	Q	D	A	R	W	A	L	F	M	V	T	I	T	Y	V	W	K	N	L	G
Secondary structure
SS confidence
Disorder																																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	T	F	V	I	Y	L	A	A	L	Q	G	V	R	R	D	L	L	E	A	A	E	I	D	G	A	S	R	W	A	V	F	R	R	V	L	L	P	Q	L	R	P	T	T	F	F	L	S	I	T	V	L	I	N	S	L	Q	V	F	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	I	N	V	M	T	R	G	G	P	E	G	T	G	T	T	T	M	V	Y	Q	V	Y	V	E	T	F	R	N	F	R	A	G	Y	G	A	T	V	A	T	I	M	F	L	V	L	L	A	V	T	Y	Y	Q	V	R	V	M	D	R	G
Secondary structure
SS confidence
Disorder																																																											?	?	?
Disorder confidence
		.	.	.
Sequence		Q	R	Q
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 74%) Beta strand ( 0%) TM helix ( 48%) (View membrane topology prediction)

Rank Aligned region

PDB 3fh6 chain F Region: 14 - 302 Aligned: 289 Modelled: 289 Confidence: 100.0% Identity: 25% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 4tqv chain I Region: 10 - 302 Aligned: 284 Modelled: 289 Confidence: 100.0% Identity: 21% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F Region: 48 - 292 Aligned: 245 Modelled: 245 Confidence: 100.0% Identity: 27% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2r6g chain G domain 1 Region: 17 - 303 Aligned: 269 Modelled: 272 Confidence: 100.0% Identity: 19% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 2 Region: 64 - 292 Aligned: 229 Modelled: 229 Confidence: 100.0% Identity: 27% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 15 - 300 Aligned: 262 Modelled: 262 Confidence: 100.0% Identity: 15% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2onk chain C Region: 19 - 297 Aligned: 249 Modelled: 267 Confidence: 100.0% Identity: 20% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 2onk chain C domain 1 Region: 19 - 297 Aligned: 249 Modelled: 267 Confidence: 100.0% Identity: 20% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain C domain 1 Region: 22 - 294 Aligned: 246 Modelled: 273 Confidence: 100.0% Identity: 19% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 22 - 294 Aligned: 246 Modelled: 273 Confidence: 100.0% Identity: 19% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 4ymu chain C Region: 63 - 301 Aligned: 213 Modelled: 219 Confidence: 100.0% Identity: 15% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 76 - 292 Aligned: 197 Modelled: 217 Confidence: 99.9% Identity: 18% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 1 Region: 17 - 76 Aligned: 56 Modelled: 60 Confidence: 95.9% Identity: 21% Fold: MalF N-terminal region-like Superfamily: MalF N-terminal region-like Family: MalF N-terminal region-like Phyre2 PDB 5kbu chain A Region: 112 - 220 Aligned: 85 Modelled: 109 Confidence: 61.5% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 4l5e chain A Region: 185 - 215 Aligned: 31 Modelled: 31 Confidence: 33.8% Identity: 23% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 2m8g chain X Region: 185 - 215 Aligned: 31 Modelled: 31 Confidence: 31.3% Identity: 19% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 1umq chain A Region: 185 - 215 Aligned: 31 Modelled: 31 Confidence: 28.4% Identity: 16% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1umq chain A Region: 185 - 215 Aligned: 31 Modelled: 31 Confidence: 28.4% Identity: 16% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 6gcs chain 6 Region: 5 - 110 Aligned: 106 Modelled: 106 Confidence: 26.2% Identity: 8% PDB header:oxidoreductase Chain: 6: PDB Molecule:nd6 subunit (nu6m); PDBTitle: cryo-em structure of respiratory complex i from yarrowia lipolytica Phyre2 PDB 1fip chain A Region: 185 - 215 Aligned: 31 Modelled: 31 Confidence: 25.5% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 1 c3fh6F_ 2 c4tqvI_ 3 c2r6gF_ 4 d2r6gg1 5 d2r6gf2 6 c4tqvJ_ 7 c2onkC_ 8 d2onkc1 9 d3d31c1 10 c3d31D_ 11 c4ymuC_ 12 d3dhwa1 13 d2r6gf1 14 c5kbuA_ 15 c4l5eA_ 16 c2m8gX_ 17 c1umqA_ 18 d1umqa_ 19 c6gcs6_ 20 d1fipa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35